ID R7C4L6_9BURK Unreviewed; 726 AA.
AC R7C4L6;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 47.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=BN641_00069 {ECO:0000313|EMBL:CDD72712.1};
OS Sutterella sp. CAG:397.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Sutterellaceae; Sutterella.
OX NCBI_TaxID=1262976 {ECO:0000313|EMBL:CDD72712.1, ECO:0000313|Proteomes:UP000018105};
RN [1] {ECO:0000313|EMBL:CDD72712.1, ECO:0000313|Proteomes:UP000018105}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:397 {ECO:0000313|Proteomes:UP000018105};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDD72712.1}.
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DR EMBL; CBHO010000203; CDD72712.1; -; Genomic_DNA.
DR AlphaFoldDB; R7C4L6; -.
DR Proteomes; UP000018105; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR017232; NtrY.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR PANTHER; PTHR43065:SF10; PEROXIDE STRESS-ACTIVATED HISTIDINE KINASE MAK3; 1.
DR PANTHER; PTHR43065; SENSOR HISTIDINE KINASE; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR PIRSF; PIRSF037532; STHK_NtrY; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Kinase {ECO:0000256|ARBA:ARBA00022777}; Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000018105};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 37..63
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 75..97
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 307..359
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 497..715
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT COILED 354..381
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 726 AA; 79323 MW; DC286B4E7B968987 CRC64;
MPRWFRYCVG SLICIAAILL FLVAAGGANS VLFDQWFPIL LVCNIFAAVT LFIFVSAVIW
RLVKRYREKL FGSRMTGKLA LVISLITVFP CLLIYLVSSQ FIGRSIDSWF DVRVEHALDS
GVALSGEIIE REQQLVKLTA LRMAKRLSSV PYADLTSELT RLKETSDITT AELFDGNAKR
LFTAADDAPQ SGLVPSKDEL AKAREQRGIT SLEGDSAEGD EPLRIRALVP AGTVRTPQGT
TRLYLQLTQQ VPPGLASNVS DLVNGFRDYQ ELVLTRGALR DIYGVTLTLA MLMAILGAVT
AALRFAGNMA APVLQLAKGT RKVAEGDLRP IREYPGNDEI NELTQSFNSM IFQIAEARTL
VENQRLQAEQ ARASLERILS NISSGVLVVD SKLHISTANV AASTILKNKR IDVGAVLPDI
EPELAEAIRN QIRLADKDSI HTELELHKGE TAEPLVIFLR GARIDLDNGD GWVIVFDDMS
AMIDAQKALA WGEVARRLAH EIKNPLTPIR LAAERLNIKL TGKLDAKDET LLHRACSTIV
SQVDAMKQMV NDFRDYARLP AAVLAPLDIN AFLKELEALY SAAGTPIELN LTEPLPAVNA
DSNQLRQVIH NLVGNALDAT VETKEPEIRI STGIVETTGS VRVVLEDNGP GFSPDILSRA
FEPYITTKAT GTGLGLPMVK KIIEEHHAKV TVMNRTDKDG HVCGASITMI FPGLQSAASR
TSDAAY
//
