ID R7CAI3_9CLOT Unreviewed; 379 AA.
AC R7CAI3;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Putative heme biosynthesis protein {ECO:0000313|EMBL:CDD74308.1};
GN ORFNames=BN737_00579 {ECO:0000313|EMBL:CDD74308.1};
OS Clostridium sp. CAG:62.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1262828 {ECO:0000313|EMBL:CDD74308.1, ECO:0000313|Proteomes:UP000018137};
RN [1] {ECO:0000313|EMBL:CDD74308.1, ECO:0000313|Proteomes:UP000018137}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:62 {ECO:0000313|Proteomes:UP000018137};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDD74308.1}.
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DR EMBL; CBHQ010000088; CDD74308.1; -; Genomic_DNA.
DR AlphaFoldDB; R7CAI3; -.
DR Proteomes; UP000018137; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd01335; Radical_SAM; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR023885; 4Fe4S-binding_SPASM_dom.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR006638; Elp3/MiaA/NifB-like_rSAM.
DR InterPro; IPR007197; rSAM.
DR NCBIfam; TIGR04085; rSAM_more_4Fe4S; 1.
DR PANTHER; PTHR11228:SF7; PQQA PEPTIDE CYCLASE; 1.
DR PANTHER; PTHR11228; RADICAL SAM DOMAIN PROTEIN; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR SFLD; SFLDG01386; main_SPASM_domain-containing; 1.
DR SFLD; SFLDS00029; Radical_SAM; 1.
DR SMART; SM00729; Elp3; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000018137};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
FT DOMAIN 26..242
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 379 AA; 44419 MW; 1CC122666100CA85 CRC64;
MVENNEKMYL ELLDFDTDKK EKWVKQRLPY SVLFELTARC NMNCVHCYLQ NVHDTKELSY
DKIIEIIDIL YEKGIVFLTF TGGEILLRKD FVDIYLYAKK KGFLVELFTN GYLFDDKIID
VLAEYPPLLV DISLYGASEN TYRKVTGLQN AFARVIQNCK KLKKAGIRVS LKSPIIDLTY
PEIKDMQMLA DKLQIPFVYT FEICNTIDRQ DMPKMHQISL NKALEYEFAN HYKQIQTEGR
KSKSNYDEII NELRTNEKVY SCNVAVNSFV VDYNGKMCPC MKLRHRGIKL EKNNYEKIWS
DFKKYSAQIA TMDYKCKGCE ALYYCDVCPA EMDFLYNDPE YRPENACKCA YIRKAFYENK
ISFDEALAEA KEDEKGGKI
//
