ID R7FVA3_9FIRM Unreviewed; 752 AA.
AC R7FVA3;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE SubName: Full=Secreted metalloprotease {ECO:0000313|EMBL:CDE19214.1};
GN ORFNames=BN797_00648 {ECO:0000313|EMBL:CDE19214.1};
OS Eubacterium sp. CAG:841.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae;
OC Eubacterium.
OX NCBI_TaxID=1262894 {ECO:0000313|EMBL:CDE19214.1, ECO:0000313|Proteomes:UP000017924};
RN [1] {ECO:0000313|EMBL:CDE19214.1, ECO:0000313|Proteomes:UP000017924}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:841 {ECO:0000313|Proteomes:UP000017924};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDE19214.1}.
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DR EMBL; CBIL010000107; CDE19214.1; -; Genomic_DNA.
DR AlphaFoldDB; R7FVA3; -.
DR STRING; 1262894.BN797_00648; -.
DR Proteomes; UP000017924; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00063; FN3; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 2.60.40.4270; Listeria-Bacteroides repeat domain; 1.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013378; InlB-like_B-rpt.
DR InterPro; IPR042229; Listeria/Bacterioides_rpt_sf.
DR NCBIfam; TIGR02543; List_Bact_rpt; 1.
DR PANTHER; PTHR41775:SF1; PEPTIDASE_M6 DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR41775; SECRETED PROTEIN-RELATED; 1.
DR Pfam; PF09479; Flg_new; 1.
DR SUPFAM; SSF49265; Fibronectin type III; 1.
DR PROSITE; PS00018; EF_HAND_1; 1.
DR PROSITE; PS50853; FN3; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:CDE19214.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Metalloprotease {ECO:0000313|EMBL:CDE19214.1};
KW Protease {ECO:0000313|EMBL:CDE19214.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000017924};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..27
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 28..752
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004445304"
FT TRANSMEM 728..747
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 494..591
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 674..724
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 674..722
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 752 AA; 82243 MW; 1571FAD644672AD4 CRC64;
MKKIYRIICC ALTLMMAFAC IAPSVFAAGK ADSDAEIKKV PLLVIIASFD ANGNGINDYD
PSNPTKLYSD KTKDYYGEQW AQTTPEDHWD RYFGDTGYTV ANYYKELTMG KMTFVPAEFT
KKAPNQTVQN GVLAVTLNRA HPTASGDAAG TILSIIRATD DYIDYAAYDT NKDGKCTQDE
LAILILNSGP DRSSTAQYYN SGSPKSYFAV HGTSQPTSLT IDGVLVISGT SGGRVCNLGE
YNKPGTIMPI GVPTHELAHN FGAEDLYHRG GHADATWPQP YRFSLQCDGN HSGGGTTPTY
LDPYQRVYLG WAEEEVVTDG EYTLYSTLTG KYKVLRVNTP DPDEYYLIEI RLKEGFEKNL
TSGGTGGIMV WHIDEGINRQ YFTKGWACSG TPENGVQHDP GIVPLFREGY DKYGKTMAVN
HPANPYYYLS DDPDTAVCNT VNFISVTTGS PSLNSYPDNW NGPKNFNVKI EVLSKPGQEM
KVRVTTELSA KVAPVTQTKA ESQTTNSITL KSTILALNGK ELTKYGVVYS KSQNFEDSKY
AEGVLSDDGK SFTTTLTGLE QSTKYFYKVV AANENLEGES TVSSTFTSSP AAEKTYFELK
LHKYLTNKDK VNTVKVDFGK KIGDALEGTY MEKKGYTFCG WYLDSAFTKA YDPEYTQDTY
SEIELFAKWE EGTSSTTSTT KVTTPETTTT TSTVETAGAE STNSTSTQET ETSTTEKPSE
SKGCKSTVGI GASFAMIVAI GTGLALGKKK TK
//
