ID R7H9A3_9FIRM Unreviewed; 575 AA.
AC R7H9A3;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=Chaperone protein DnaK {ECO:0000256|ARBA:ARBA00014415};
DE AltName: Full=Chaperone protein dnaK {ECO:0000256|ARBA:ARBA00017249};
DE AltName: Full=HSP70 {ECO:0000256|ARBA:ARBA00033103};
DE AltName: Full=Heat shock 70 kDa protein {ECO:0000256|ARBA:ARBA00030945};
DE AltName: Full=Heat shock protein 70 {ECO:0000256|ARBA:ARBA00030019};
GN ORFNames=BN634_00008 {ECO:0000313|EMBL:CDE35886.1};
OS Eubacterium sp. CAG:38.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae;
OC Eubacterium.
OX NCBI_TaxID=1262889 {ECO:0000313|EMBL:CDE35886.1, ECO:0000313|Proteomes:UP000017954};
RN [1] {ECO:0000313|EMBL:CDE35886.1, ECO:0000313|Proteomes:UP000017954}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:38 {ECO:0000313|Proteomes:UP000017954};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Acts as a chaperone. {ECO:0000256|ARBA:ARBA00002290}.
CC -!- SIMILARITY: Belongs to the heat shock protein 70 family.
CC {ECO:0000256|ARBA:ARBA00007381, ECO:0000256|RuleBase:RU003322}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDE35886.1}.
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DR EMBL; CBIU010000044; CDE35886.1; -; Genomic_DNA.
DR AlphaFoldDB; R7H9A3; -.
DR STRING; 1262889.BN634_00008; -.
DR Proteomes; UP000017954; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR Gene3D; 3.30.420.40; -; 2.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR018181; Heat_shock_70_CS.
DR InterPro; IPR029047; HSP70_peptide-bd_sf.
DR InterPro; IPR013126; Hsp_70_fam.
DR PANTHER; PTHR19375; HEAT SHOCK PROTEIN 70KDA; 1.
DR PANTHER; PTHR19375:SF184; STRESS-70 PROTEIN, MITOCHONDRIAL; 1.
DR Pfam; PF00012; HSP70; 2.
DR PRINTS; PR00301; HEATSHOCK70.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR SUPFAM; SSF100920; Heat shock protein 70kD (HSP70), peptide-binding domain; 1.
DR PROSITE; PS00297; HSP70_1; 1.
DR PROSITE; PS00329; HSP70_2; 1.
DR PROSITE; PS01036; HSP70_3; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU003322};
KW Chaperone {ECO:0000256|ARBA:ARBA00023186};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU003322};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000017954};
KW Stress response {ECO:0000256|ARBA:ARBA00023016}.
FT COILED 223..250
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 575 AA; 65125 MW; A05DAEC93BB8EEA5 CRC64;
MAVIGIDLGT TNSLAGVWQD GKVVLIPNAF GEYLTPSVVG IGKNQEVFVG SVAKEMLATQ
PYDTFREFKR NMGTNFLYGN GRKKYRAEEL SAFVLRRLKE DAEKFLGEEV TEAVISVPAY
FDDNKRNATK NAGRLAGLKV ERLINEPSAV ALKHHTAEKG AESFIVFDFG GGTLDVSLVE
AFDNVVEIQA VAGDNYLGGK DFNEIIAQDF YEQNQISEAY LTKNEQENVL KEAEAVKKEL
TDKNEAERQV YIKGEAYTLK MTNQRLIHLS AELFSRMAKP IAKVINMVGI ELEELDKVIL
VGGSSKMPVV QQYIKGLLGD KVPVVLEENP DESVAYGVGM AAAIKERTGD IKDMLLTDIC
PFSLGTELYD GSFSPVIEKN ETLPCKRTMY YTTVRNNQIT MNFPIYQGEN IKASDNLKIG
EINLKRLPKA PEGEQVVKVT FIYDINGILD VNIESSVEKV HKVIVNKQIG LSEKELEKRV
EQLEKMPLHP WEKEENRLLF EKAERLYEQT TPKNRQVIQE CLRYFKELLI NTKGRKVRQE
YVRIMAILDY IEQNQVDFGP YDETFWQKEE EDTDE
//
