ID   R7HHN6_9FIRM            Unreviewed;       334 AA.
AC   R7HHN6;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=Putative dihydroflavonol 4-reductase {ECO:0000313|EMBL:CDE39149.1};
GN   ORFNames=BN608_00414 {ECO:0000313|EMBL:CDE39149.1};
OS   Firmicutes bacterium CAG:321.
OC   Bacteria; Bacillota.
OX   NCBI_TaxID=1263018 {ECO:0000313|EMBL:CDE39149.1, ECO:0000313|Proteomes:UP000017979};
RN   [1] {ECO:0000313|EMBL:CDE39149.1, ECO:0000313|Proteomes:UP000017979}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:321 {ECO:0000313|Proteomes:UP000017979};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDE39149.1}.
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DR   EMBL; CBIW010000031; CDE39149.1; -; Genomic_DNA.
DR   AlphaFoldDB; R7HHN6; -.
DR   Proteomes; UP000017979; Unassembled WGS sequence.
DR   GO; GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:InterPro.
DR   GO; GO:0006694; P:steroid biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR002225; 3Beta_OHSteriod_DH/Estase.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR48079; PROTEIN YEEZ; 1.
DR   PANTHER; PTHR48079:SF6; PROTEIN YEEZ; 1.
DR   Pfam; PF01073; 3Beta_HSD; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
FT   DOMAIN          6..226
FT                   /note="3-beta hydroxysteroid dehydrogenase/isomerase"
FT                   /evidence="ECO:0000259|Pfam:PF01073"
SQ   SEQUENCE   334 AA;  37776 MW;  8BA86411ADF0E45B CRC64;
     MKRIYIVTGA NGFLGNNIIR KLEQDDNNEI RAFVLNGESI KSLEKLKCKI YYGDVTKKET
     LLPLFENIDG KEVFVIHCAA VVYIKTKYNP LVYNVNVNGT KNVVDKVIET KAKLIYISSV
     HAIPEKENND LIEEITDFNP DEVHGLYAKT KAEAAKYVMN AVKNKNLNAC IIHPSGIIGP
     YDYGNSHLTE LVREVSNGKL FATVKGGYDF VDVRDVAAAI ITASKKDNKG ECYILSNRYI
     TIKELSDLIC DVQGIKRIKI VLPICLAKII APFFEVYYNL KKQTPLFTKY SLYTLSSNSN
     FSNKKAKEEL GYKNRDMKDT IKDTISWLNK GEEK
//