ID   R7I3X2_9CLOT            Unreviewed;       622 AA.
AC   R7I3X2;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 28.
DE   RecName: Full=Transglutaminase-like domain-containing protein {ECO:0000259|SMART:SM00460};
GN   ORFNames=BN648_00418 {ECO:0000313|EMBL:CDE46176.1};
OS   Clostridium sp. CAG:411.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=1262802 {ECO:0000313|EMBL:CDE46176.1, ECO:0000313|Proteomes:UP000018022};
RN   [1] {ECO:0000313|EMBL:CDE46176.1, ECO:0000313|Proteomes:UP000018022}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:411 {ECO:0000313|Proteomes:UP000018022};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDE46176.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CBIY010000157; CDE46176.1; -; Genomic_DNA.
DR   AlphaFoldDB; R7I3X2; -.
DR   STRING; 1262802.BN648_00418; -.
DR   Proteomes; UP000018022; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 3.10.620.30; -; 1.
DR   InterPro; IPR038765; Papain-like_cys_pep_sf.
DR   InterPro; IPR002931; Transglutaminase-like.
DR   PANTHER; PTHR42736; PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE; 1.
DR   PANTHER; PTHR42736:SF1; PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE; 1.
DR   Pfam; PF01841; Transglut_core; 1.
DR   SMART; SM00460; TGc; 1.
DR   SUPFAM; SSF54001; Cysteine proteinases; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018022};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        21..40
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        70..88
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        100..118
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        514..535
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          385..460
FT                   /note="Transglutaminase-like"
FT                   /evidence="ECO:0000259|SMART:SM00460"
FT   REGION          461..508
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        470..508
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   622 AA;  71892 MW;  43EE4F12D6B434F3 CRC64;
     MIIQREERKG KGHREKWIGT ILVVLAFAGI LFFRTGMLLL GNRCLRVVEK RFGILLPEYS
     CHPYQATFEQ VGAIATIVLL LIGVYLLGRE GWKRGEKSHF VVLVSFFLLL GIMLAIHFSG
     KNWWDRAQNW CEKQVKMVRY GGETSTLPKG DFRGIGERKK KKGVALQVVM EKPADLYLRG
     FVGAKYTGSG WKSMDGDAIY ASKEVLRKLQ KNDFSYASQL GSSAKFCQVG EENSIAIKVK
     GVDREYVYTP YGLLEQELPT SSSYREDGLW SKGIRGQKSY QYKAYSNVVS NYPSISMKIY
     HAKGAEEYLI AESYYNTYVY EKYLTIPEEI KNYLKKEVGE VKTDKSHMSY EEANAIVSDF
     LAQHLSYSEK VKKYAGASDF VLWVLQGEKK GYDLHYATVA TFLYRYLGIP ARYVEGYCVT
     KEDVAYKTSY DMIEVSEDHG HAWVEIYQDG AGFIPMEVDP SYQGKMSRPK QRAEGTKNRV
     KERSDTAKEE NSIHKTNPSK AEKQTKDKKR NDTWIYESVC VALLLLVCFI VFLLVKNKAQ
     RKNMHRKIER QYRKLLKRLK RKGAVIQLPP TMWIKQMEEK VKGCTLQELK MAIQIGEKNR
     YSKETCKEEE WKLLKYVYRK IR
//