ID R7L2B3_9FIRM Unreviewed; 624 AA.
AC R7L2B3;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Preprotein translocase YidC subunit {ECO:0000313|EMBL:CDE82750.1};
GN ORFNames=BN622_00560 {ECO:0000313|EMBL:CDE82750.1};
OS Ruminococcus sp. CAG:353.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC Ruminococcus.
OX NCBI_TaxID=1262955 {ECO:0000313|EMBL:CDE82750.1, ECO:0000313|Proteomes:UP000017936};
RN [1] {ECO:0000313|EMBL:CDE82750.1, ECO:0000313|Proteomes:UP000017936}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:353 {ECO:0000313|Proteomes:UP000017936};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU003945}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU003945}.
CC -!- SIMILARITY: Belongs to the OXA1/ALB3/YidC family.
CC {ECO:0000256|RuleBase:RU003945}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDE82750.1}.
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DR EMBL; CBJQ010000236; CDE82750.1; -; Genomic_DNA.
DR AlphaFoldDB; R7L2B3; -.
DR Proteomes; UP000017936; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0032977; F:membrane insertase activity; IEA:InterPro.
DR GO; GO:0051205; P:protein insertion into membrane; IEA:UniProt.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR CDD; cd20070; 5TM_YidC_Alb3; 1.
DR Gene3D; 3.40.50.12580; -; 1.
DR InterPro; IPR043148; TagF_C.
DR InterPro; IPR001708; YidC/ALB3/OXA1/COX18.
DR InterPro; IPR028055; YidC/Oxa/ALB_C.
DR InterPro; IPR047196; YidC_ALB_C.
DR NCBIfam; TIGR03592; yidC_oxa1_cterm; 1.
DR PANTHER; PTHR12428:SF65; INNER MEMBRANE PROTEIN ALBINO3, CHLOROPLASTIC; 1.
DR PANTHER; PTHR12428; OXA1; 1.
DR Pfam; PF02096; 60KD_IMP; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000017936};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU003945};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022927}.
FT TRANSMEM 20..44
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 85..105
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 137..155
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 176..200
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 22..213
FT /note="Membrane insertase YidC/Oxa/ALB C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02096"
SQ SEQUENCE 624 AA; 70622 MW; 86F9FC59755CA178 CRC64;
MEWFSKFLGW LFSLVYSING NYLAALILFT LLTKIILLPL SIIVHKNSIK LVKLTPEINN
IKYSCYGDKD LINTKTLELY KKEKYNPLVS VFPLIVQLIL LMGVIEVVST PEYSGLTVSD
MLSCGIDFSL VSKDVGGLYY LFPIIAAVSS MIMCITQNIS QALQAEQSKL NKYGMMALST
ALSLYLGFFV NAGVAAYWIL SNLMSIAQMY ILNAVISPKK YIDYAALEES KKKLKAIEGS
EKSMDRELKK RQHDDYKRFF SIANKHVVFY SEQSGFYKYF KGLIEYLISH SNITIHYVTS
DPNDVIFDIA KEQKQIKPYF IGENKLISLF LKMDAKIVVM TMPDLDNFHI KRSYVSSDVE
YIYMDHGLSS INMLTRKGAV DHFDTVFCAG QHIIDEIKAT EEHYGLPHKN LIAYGYGFMD
GLIKICSTDP TIASGDFILL APSHQKDNIL DSCLEPVIEG LKSTGYKVIL RPHPQYIRRY
PDKWKRISAQ YSSDPQVITE SDFSSNTSIY QAALVVTDWS NIGYEYSFST LRPVMFINTP
MKVINPDYKE IGVVPIDLSL RSEIGIEVTG RSADEVAEAA EKLLKTKCFS AEQISKARDR
SLFNVGKSDE VGGKYILSRL SQKK
//
