ID R7N4P7_9FIRM Unreviewed; 512 AA.
AC R7N4P7;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE RecName: Full=Flagellar hook-associated protein 2 {ECO:0000256|RuleBase:RU362066};
DE Short=HAP2 {ECO:0000256|RuleBase:RU362066};
DE AltName: Full=Flagellar cap protein {ECO:0000256|RuleBase:RU362066};
GN ORFNames=BN816_02464 {ECO:0000313|EMBL:CDF07775.1};
OS Firmicutes bacterium CAG:95.
OC Bacteria; Bacillota.
OX NCBI_TaxID=1262988 {ECO:0000313|EMBL:CDF07775.1, ECO:0000313|Proteomes:UP000018182};
RN [1] {ECO:0000313|EMBL:CDF07775.1, ECO:0000313|Proteomes:UP000018182}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:95 {ECO:0000313|Proteomes:UP000018182};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for morphogenesis and for the elongation of the
CC flagellar filament by facilitating polymerization of the flagellin
CC monomers at the tip of growing filament. Forms a capping structure,
CC which prevents flagellin subunits (transported through the central
CC channel of the flagellum) from leaking out without polymerization at
CC the distal end. {ECO:0000256|RuleBase:RU362066}.
CC -!- SUBUNIT: Homopentamer. {ECO:0000256|ARBA:ARBA00011255,
CC ECO:0000256|RuleBase:RU362066}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|RuleBase:RU362066}.
CC Bacterial flagellum {ECO:0000256|RuleBase:RU362066}.
CC -!- SIMILARITY: Belongs to the FliD family. {ECO:0000256|ARBA:ARBA00009764,
CC ECO:0000256|RuleBase:RU362066}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDF07775.1}.
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DR EMBL; CBKF010000162; CDF07775.1; -; Genomic_DNA.
DR AlphaFoldDB; R7N4P7; -.
DR STRING; 1262988.BN816_02464; -.
DR Proteomes; UP000018182; Unassembled WGS sequence.
DR GO; GO:0009421; C:bacterial-type flagellum filament cap; IEA:InterPro.
DR GO; GO:0009424; C:bacterial-type flagellum hook; IEA:UniProtKB-UniRule.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR InterPro; IPR040026; FliD.
DR InterPro; IPR010809; FliD_C.
DR InterPro; IPR003481; FliD_N.
DR PANTHER; PTHR30288; FLAGELLAR CAP/ASSEMBLY PROTEIN FLID; 1.
DR PANTHER; PTHR30288:SF0; FLAGELLAR HOOK-ASSOCIATED PROTEIN 2; 1.
DR Pfam; PF07195; FliD_C; 1.
DR Pfam; PF02465; FliD_N; 1.
PE 3: Inferred from homology;
KW Bacterial flagellum {ECO:0000256|ARBA:ARBA00023143,
KW ECO:0000256|RuleBase:RU362066};
KW Cell projection {ECO:0000313|EMBL:CDF07775.1};
KW Cilium {ECO:0000313|EMBL:CDF07775.1};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Flagellum {ECO:0000313|EMBL:CDF07775.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000018182};
KW Secreted {ECO:0000256|RuleBase:RU362066}.
FT DOMAIN 10..105
FT /note="Flagellar hook-associated protein 2 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02465"
FT DOMAIN 235..500
FT /note="Flagellar hook-associated protein 2 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07195"
SQ SEQUENCE 512 AA; 55648 MW; 655E5A1E706CFDED CRC64;
MAMRMTGMYS GMDTESIIQE LVSAKRTKVD DVKKKQTKLE WKQDAWKDLN TKLKNLQSKY
ISNMRFASSY MKKTTAVSNS SAVSVITGEN AVNGVQSLEV KQLAKTGYLT GAQIKASGSG
SLTALSKLSD LAGSDGIGNG GQISIKAGDK DLTLDVTADT TISDVLTKLK EAGLNANFDE
KQQRFFISAK TSGASNDFSI TAAGSNGQAA LKALGIQLNP DGDPTAEGYA KKIDGQDAKI
ELNGATFTNN TNVFEINGLT FTALSETKAG EAVTITTQDD TDGIYDMIKG FLKEYNTIMN
EMDKLYNAAS ASKYQPLTDD EKDAMSDTEV EKYEKKIKDS LLRRDSTLST IRSKLTSVMS
SGTTVDGKQM HLSDFGIDTL SYFTAAENEK NAYHIDGDPD DENTSGNADK LKSMIASDPD
TVVSFFSSLH KELYSTMDGL SKAVEGYRSY GSFYDDKKMK SDYSDYTTKI AEMEKKLNAY
EDKWYSKFSK METALAKMQS NASAITGLLG GS
//
