ID R7N7K2_9FIRM Unreviewed; 495 AA.
AC R7N7K2;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE SubName: Full=Threonine synthase {ECO:0000313|EMBL:CDF08626.1};
GN ORFNames=BN816_00605 {ECO:0000313|EMBL:CDF08626.1};
OS Firmicutes bacterium CAG:95.
OC Bacteria; Bacillota.
OX NCBI_TaxID=1262988 {ECO:0000313|EMBL:CDF08626.1, ECO:0000313|Proteomes:UP000018182};
RN [1] {ECO:0000313|EMBL:CDF08626.1, ECO:0000313|Proteomes:UP000018182}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:95 {ECO:0000313|Proteomes:UP000018182};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933,
CC ECO:0000256|PIRSR:PIRSR604450-51};
CC -!- SIMILARITY: Belongs to the threonine synthase family.
CC {ECO:0000256|ARBA:ARBA00005517}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDF08626.1}.
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DR EMBL; CBKF010000236; CDF08626.1; -; Genomic_DNA.
DR AlphaFoldDB; R7N7K2; -.
DR STRING; 1262988.BN816_00605; -.
DR Proteomes; UP000018182; Unassembled WGS sequence.
DR CDD; cd01560; Thr-synth_2; 1.
DR Gene3D; 3.40.50.1100; -; 2.
DR Gene3D; 3.90.1380.10; Threonine synthase, N-terminal domain; 1.
DR InterPro; IPR029144; Thr_synth_N.
DR InterPro; IPR037158; Thr_synth_N_sf.
DR InterPro; IPR004450; Thr_synthase-like.
DR InterPro; IPR001926; TrpB-like_PALP.
DR InterPro; IPR036052; TrpB-like_PALP_sf.
DR NCBIfam; TIGR00260; thrC; 1.
DR PANTHER; PTHR43515; THREONINE SYNTHASE-LIKE 1; 1.
DR PANTHER; PTHR43515:SF1; THREONINE SYNTHASE-LIKE 1; 1.
DR Pfam; PF00291; PALP; 1.
DR Pfam; PF14821; Thr_synth_N; 1.
DR SUPFAM; SSF53686; Tryptophan synthase beta subunit-like PLP-dependent enzymes; 1.
PE 3: Inferred from homology;
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW ECO:0000256|PIRSR:PIRSR604450-51};
KW Reference proteome {ECO:0000313|Proteomes:UP000018182}.
FT DOMAIN 3..78
FT /note="Threonine synthase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF14821"
FT DOMAIN 99..422
FT /note="Tryptophan synthase beta chain-like PALP"
FT /evidence="ECO:0000259|Pfam:PF00291"
FT MOD_RES 110
FT /note="N6-(pyridoxal phosphate)lysine"
FT /evidence="ECO:0000256|PIRSR:PIRSR604450-51"
SQ SEQUENCE 495 AA; 55308 MW; AC2F4B8B94CE98BD CRC64;
MLYNSTRTAG KQVKASEAIL RGLSEDGGLF VPESIPALDK SLKELSQMTY QQVAYEVMKL
YLTDFTEEEL KNCIEKAYDE KFDTEEIAPL VHAEDAYYLE LFHGATIAFK DMALSILPHL
LTTSAKKNHV TNEIVILTAT SGDTGKAALA GFADVEGTRI VVFYPKNGVS PIQEKQMVTQ
KGKNTFVVAI HGNFDDAQTG VKKIFNDRDL EKKLNESGFQ LSSANSINIG RLLPQVAYYV
YAYVKLLAEE QIEDGELVNM VVPTGNFGNI LAAYYAKKMG VPIGKLICAS NENKVLYDFF
RTGTYDKNRE FVLTTSPSMD ILISSNLERL IYHIAGDNAD RNRELMESLN QTGVYTISEE
MKAELKDFYG AYASEQETAK EIHDLYENTG YIIDTHTAVA SSVYKKYKKE TGDQTKTVVV
STASPYKFTR SVMTAIDEGY ANMEDFALVD ELEKLSGVPV PNAIQEIRTA PVLHKTECDK
EDMEKTVLSF LERKI
//
