ID R7P5Z9_9CLOT Unreviewed; 381 AA.
AC R7P5Z9;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Transposase IS605 OrfB family {ECO:0000313|EMBL:CDF20481.1};
GN ORFNames=BN733_00649 {ECO:0000313|EMBL:CDF20481.1};
OS Clostridium sp. CAG:609.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1262827 {ECO:0000313|EMBL:CDF20481.1, ECO:0000313|Proteomes:UP000018389};
RN [1] {ECO:0000313|EMBL:CDF20481.1, ECO:0000313|Proteomes:UP000018389}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:609 {ECO:0000313|Proteomes:UP000018389};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: In the C-terminal section; belongs to the transposase 35
CC family. {ECO:0000256|ARBA:ARBA00008761}.
CC -!- SIMILARITY: In the N-terminal section; belongs to the transposase 2
CC family. {ECO:0000256|ARBA:ARBA00011044}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDF20481.1}.
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DR EMBL; CBKL010000029; CDF20481.1; -; Genomic_DNA.
DR AlphaFoldDB; R7P5Z9; -.
DR STRING; 1262827.BN733_00649; -.
DR Proteomes; UP000018389; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR GO; GO:0032196; P:transposition; IEA:UniProtKB-KW.
DR InterPro; IPR010095; Cas12f1-like_TNB.
DR InterPro; IPR001959; Transposase.
DR InterPro; IPR021027; Transposase_put_HTH.
DR NCBIfam; NF040570; guided_TnpB; 1.
DR NCBIfam; TIGR01766; IS200/IS605 family accessory protein TnpB-like domain; 1.
DR PANTHER; PTHR30405:SF20; RNA-GUIDED DNA ENDONUCLEASE INSQ-RELATED; 1.
DR PANTHER; PTHR30405; TRANSPOSASE; 1.
DR Pfam; PF12323; HTH_OrfB_IS605; 1.
DR Pfam; PF01385; OrfB_IS605; 1.
DR Pfam; PF07282; OrfB_Zn_ribbon; 1.
PE 3: Inferred from homology;
KW DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Endonuclease {ECO:0000256|ARBA:ARBA00022759};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Transposition {ECO:0000256|ARBA:ARBA00022578};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 1..47
FT /note="Transposase putative helix-turn-helix"
FT /evidence="ECO:0000259|Pfam:PF12323"
FT DOMAIN 174..285
FT /note="Probable transposase IS891/IS1136/IS1341"
FT /evidence="ECO:0000259|Pfam:PF01385"
FT DOMAIN 298..368
FT /note="Cas12f1-like TNB"
FT /evidence="ECO:0000259|Pfam:PF07282"
SQ SEQUENCE 381 AA; 44985 MW; 7554EBE8C87AF4EE CRC64;
MIIYKAYKFR MDPTLEQKRL INQNLGSVRF IHNHFLEEKI KTYETYKRVV SPYLQMKSLR
KLKDEYPWLK EVDHCSLMTT IFNLDDTFKS MIKEGKYPNY KSKYNKESYT TNNELKTWGN
IKYYSVRLNL KDRIVILPRL KSVTIRGYKK LSSINGKIKS ATVSKVANKF YVSLLVEMSI
EVPENKCEKI LGIDLGIKNY IVTSDGKKYK NEININEQRL KGLHRALSRS TKGSRNREKV
IIKIQKFYRS LKNKRKTQIC EIVKRILQEN DVVVTEDLDV KKMYQTKSIA VKLRDVPFTN
FIETMSYKAK WQGKKVIKID RYFPSSQVCS DCGYQNKTLK DLSVREWICP KCYAHHDRDI
NASINIKNEG IKILLKQLNL Y
//
