ID R7PA76_9BACT Unreviewed; 375 AA.
AC R7PA76;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Alpha-L-fucosidase {ECO:0000313|EMBL:CDF21996.1};
GN ORFNames=BN736_01724 {ECO:0000313|EMBL:CDF21996.1};
OS Prevotella sp. CAG:617.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC Prevotella.
OX NCBI_TaxID=1262933 {ECO:0000313|EMBL:CDF21996.1, ECO:0000313|Proteomes:UP000018057};
RN [1] {ECO:0000313|EMBL:CDF21996.1, ECO:0000313|Proteomes:UP000018057}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:617 {ECO:0000313|Proteomes:UP000018057};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-
CC 1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the
CC carbohydrate moieties of glycoproteins.
CC {ECO:0000256|ARBA:ARBA00004071}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDF21996.1}.
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DR EMBL; CBKM010000093; CDF21996.1; -; Genomic_DNA.
DR AlphaFoldDB; R7PA76; -.
DR STRING; 1262933.BN736_01724; -.
DR Proteomes; UP000018057; Unassembled WGS sequence.
DR GO; GO:0004560; F:alpha-L-fucosidase activity; IEA:InterPro.
DR GO; GO:0006004; P:fucose metabolic process; IEA:InterPro.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR016286; FUC_metazoa-typ.
DR InterPro; IPR000933; Glyco_hydro_29.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR10030; ALPHA-L-FUCOSIDASE; 1.
DR PANTHER; PTHR10030:SF46; ALPHA-L-FUCOSIDASE-RELATED; 1.
DR Pfam; PF01120; Alpha_L_fucos; 1.
DR PIRSF; PIRSF001092; Alpha-L-fucosidase; 1.
DR PRINTS; PR00741; GLHYDRLASE29.
DR SMART; SM00812; Alpha_L_fucos; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000018057};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..375
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004442004"
FT SITE 277
FT /note="May be important for catalysis"
FT /evidence="ECO:0000256|PIRSR:PIRSR001092-1"
SQ SEQUENCE 375 AA; 42225 MW; 9E682AD988EEA537 CRC64;
MTKRIVALGW AGALMVFFMA AQAQSVKMNP KTDNALLTRF QDAKLGLFVH WMACHTPTTG
DSWSIGRGTP KTVADSITMS WNPEKFDARR IVDVAVQSGC RYMVVISKHH DGFCIWPSAY
SDFDLDRGAF HRDMLKELGD ECRRRGLLFG IYYSIADIDY CGWTRMPGAG EPVPEPRKGK
ADFVSFVHNQ TRELIQRYQP DILWLDGFWL DPLWSAREGR HLYQVIKSAK SDVLSTRLSV
TKDSTGQETF WTDGSSGDYF SMEAKTTDAP DFPWEACTSV TYPVYAYEPD AKMLSGKALI
DLFSRTLCGN GNLLVNIGPK PTGEMPEEQV ARLHELTDWI EAHQDAVYGT RGGPYRQTDQ
LGSTYRGKKL VSSYS
//
