ID   R7PRU1_9FIRM            Unreviewed;       263 AA.
AC   R7PRU1;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 31.
DE   SubName: Full=CRISPR-associated endonuclease Cas1 {ECO:0000313|EMBL:CDF27766.1};
GN   ORFNames=BN722_00462 {ECO:0000313|EMBL:CDF27766.1};
OS   Dialister sp. CAG:588.
OC   Bacteria; Bacillota; Negativicutes; Veillonellales; Veillonellaceae;
OC   Dialister; environmental samples.
OX   NCBI_TaxID=1262871 {ECO:0000313|EMBL:CDF27766.1, ECO:0000313|Proteomes:UP000018383};
RN   [1] {ECO:0000313|EMBL:CDF27766.1, ECO:0000313|Proteomes:UP000018383}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:588 {ECO:0000313|Proteomes:UP000018383};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBUNIT: Homodimer, forms a heterotetramer with a Cas2 homodimer.
CC       {ECO:0000256|ARBA:ARBA00038592}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDF27766.1}.
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DR   EMBL; CBKO010000175; CDF27766.1; -; Genomic_DNA.
DR   AlphaFoldDB; R7PRU1; -.
DR   Proteomes; UP000018383; Unassembled WGS sequence.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   GO; GO:0043571; P:maintenance of CRISPR repeat elements; IEA:InterPro.
DR   Gene3D; 1.20.120.920; CRISPR-associated endonuclease Cas1, C-terminal domain; 1.
DR   InterPro; IPR002729; CRISPR-assoc_Cas1.
DR   InterPro; IPR042206; CRISPR-assoc_Cas1_C.
DR   NCBIfam; TIGR00287; cas1; 1.
DR   PANTHER; PTHR34353; CRISPR-ASSOCIATED ENDONUCLEASE CAS1 1; 1.
DR   PANTHER; PTHR34353:SF2; CRISPR-ASSOCIATED ENDONUCLEASE CAS1 1; 1.
DR   Pfam; PF01867; Cas_Cas1; 1.
PE   4: Predicted;
KW   Antiviral defense {ECO:0000256|ARBA:ARBA00023118};
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Endonuclease {ECO:0000256|ARBA:ARBA00022759, ECO:0000313|EMBL:CDF27766.1};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW   Manganese {ECO:0000256|ARBA:ARBA00023211};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018383}.
SQ   SEQUENCE   263 AA;  30550 MW;  A2664AA175BEDBA4 CRC64;
     MGETKGNVLL RRKQYRIANS EESLDFVKNI IYAKIYNSRK VLQRASRDHG NFIDKEKIEK
     SIHNLEILMK DVKSANNKDS IRGVEGLASK YYFECFNEMI IKQKEDFRFE SRNRRPPTDR
     VNALLSFLYT MLILDVQASI EALGIDSYVG FFHTDRPGRA SMALDMVEDL RAYLVDRLVL
     SLINLQVIND SHFETKENEA VLLNDKGREL VLKKWNEKKQ QVITHPYIEE KIKIGLIPHV
     QGMLFSAYMR GDIDAYPPFL IKG
//