ID R7QR54_CHOCR Unreviewed; 350 AA.
AC R7QR54;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=TIR domain-containing protein {ECO:0000313|EMBL:CDF40243.1};
GN ORFNames=CHC_T00008460001 {ECO:0000313|EMBL:CDF40243.1};
OS Chondrus crispus (Carrageen Irish moss) (Polymorpha crispa).
OC Eukaryota; Rhodophyta; Florideophyceae; Rhodymeniophycidae; Gigartinales;
OC Gigartinaceae; Chondrus.
OX NCBI_TaxID=2769 {ECO:0000313|EMBL:CDF40243.1, ECO:0000313|Proteomes:UP000012073};
RN [1] {ECO:0000313|Proteomes:UP000012073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Stackhouse {ECO:0000313|Proteomes:UP000012073};
RX PubMed=23503846; DOI=10.1073/pnas.1221259110;
RA Collen J., Porcel B., Carre W., Ball S.G., Chaparro C., Tonon T.,
RA Barbeyron T., Michel G., Noel B., Valentin K., Elias M., Artiguenave F.,
RA Arun A., Aury J.M., Barbosa-Neto J.F., Bothwell J.H., Bouget F.Y.,
RA Brillet L., Cabello-Hurtado F., Capella-Gutierrez S., Charrier B.,
RA Cladiere L., Cock J.M., Coelho S.M., Colleoni C., Czjzek M., Da Silva C.,
RA Delage L., Denoeud F., Deschamps P., Dittami S.M., Gabaldon T.,
RA Gachon C.M., Groisillier A., Herve C., Jabbari K., Katinka M., Kloareg B.,
RA Kowalczyk N., Labadie K., Leblanc C., Lopez P.J., McLachlan D.H.,
RA Meslet-Cladiere L., Moustafa A., Nehr Z., Nyvall Collen P., Panaud O.,
RA Partensky F., Poulain J., Rensing S.A., Rousvoal S., Samson G.,
RA Symeonidi A., Weissenbach J., Zambounis A., Wincker P., Boyen C.;
RT "Genome structure and metabolic features in the red seaweed Chondrus
RT crispus shed light on evolution of the Archaeplastida.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:5247-5252(2013).
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DR EMBL; HG002147; CDF40243.1; -; Genomic_DNA.
DR RefSeq; XP_005710537.1; XM_005710480.1.
DR AlphaFoldDB; R7QR54; -.
DR EnsemblPlants; CDF40243; CDF40243; CHC_T00008460001.
DR GeneID; 17318255; -.
DR Gramene; CDF40243; CDF40243; CHC_T00008460001.
DR KEGG; ccp:CHC_T00008460001; -.
DR OrthoDB; 1127757at2759; -.
DR PhylomeDB; R7QR54; -.
DR Proteomes; UP000012073; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR InterPro; IPR000157; TIR_dom.
DR InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR PANTHER; PTHR32009:SF97; TIR DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR32009; TMV RESISTANCE PROTEIN N-LIKE; 1.
DR Pfam; PF13676; TIR_2; 1.
DR SMART; SM00255; TIR; 1.
DR SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR PROSITE; PS50104; TIR; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000012073};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 323..344
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 90..242
FT /note="TIR"
FT /evidence="ECO:0000259|PROSITE:PS50104"
FT REGION 285..304
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 350 AA; 39602 MW; AA2DC285CDE6BD7D CRC64;
MKHYLRTQCR SDLNGCGGEW TASFRLPADW AKNGTEKGLW NLDGECTDCE EAWRLSQLMP
EMEKYYGPAR PEALKPLTVI QRTSKEVGMK AVDVFISHAG PDKWTIASPL FDKLRGEGFS
CFLDKKSMKA GDCASEEMIA AMESAKIGVF ILSPEFAARR WPMKELRCFL RRYRDAQSSG
ATLPILIPVF YRLRISECRS FKPEQYVDEN GRDLFEAEKF YTEERQNEAT MAMVKDELRE
VTTLLGIENE AASNDVLDPL ASGFRKMLVE RIVYSVKEAR EARQQQEAKG VGIPQTGREG
DCSTVPKGSD GLRFPKWRIA GRLLAYSAVV FTMAYSAVVF TNLFCFSCNE
//
