ID   R7R8X5_9FIRM            Unreviewed;       430 AA.
AC   R7R8X5;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 27.
DE   RecName: Full=Trk system potassium uptake protein TrkA {ECO:0008006|Google:ProtNLM};
GN   ORFNames=BN450_02719 {ECO:0000313|EMBL:CDF46321.1};
OS   Roseburia sp. CAG:100.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Roseburia.
OX   NCBI_TaxID=1262940 {ECO:0000313|EMBL:CDF46321.1, ECO:0000313|Proteomes:UP000018092};
RN   [1] {ECO:0000313|EMBL:CDF46321.1, ECO:0000313|Proteomes:UP000018092}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:100 {ECO:0000313|Proteomes:UP000018092};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDF46321.1}.
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DR   EMBL; CBKV010000266; CDF46321.1; -; Genomic_DNA.
DR   AlphaFoldDB; R7R8X5; -.
DR   Proteomes; UP000018092; Unassembled WGS sequence.
DR   GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR   Gene3D; 3.30.70.1450; Regulator of K+ conductance, C-terminal domain; 2.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR006037; RCK_C.
DR   InterPro; IPR036721; RCK_C_sf.
DR   InterPro; IPR003148; RCK_N.
DR   PANTHER; PTHR43833; POTASSIUM CHANNEL PROTEIN 2-RELATED-RELATED; 1.
DR   PANTHER; PTHR43833:SF5; TRK SYSTEM POTASSIUM UPTAKE PROTEIN TRKA; 1.
DR   Pfam; PF02080; TrkA_C; 2.
DR   Pfam; PF02254; TrkA_N; 2.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 2.
DR   SUPFAM; SSF116726; TrkA C-terminal domain-like; 2.
DR   PROSITE; PS51202; RCK_C; 2.
DR   PROSITE; PS51201; RCK_N; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000018092}.
FT   DOMAIN          113..196
FT                   /note="RCK C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51202"
FT   DOMAIN          204..328
FT                   /note="RCK N-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51201"
FT   DOMAIN          346..427
FT                   /note="RCK C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51202"
SQ   SEQUENCE   430 AA;  47504 MW;  83BD84B17CBFE12E CRC64;
     MIDINPERLQ PALSALDIQG LVGNSTSFVT QQESGIEEAD LFIAVTGKDE INLLSCLIAK
     KASNCQTIAR VRNPEYSKEI TYLKQCMGMS MAINPELASA KEIAHLIQVP DAMEIDSFAK
     GKVDLLRVAI SQNSPLHNMK VQEFSKHFNH EILICILVHE HQVSIPNGET ILQAGDTISV
     IIPKDKIRDF YKATKLSTLK EIKDVIIAGG GTISYYLSTL LLSSGIHVKI LEKDKDRCDF
     LSVALPDATV IYADATDHSI LQEEGLANTD AFVALTNMDE ENVFLSLYAK KLSPRCKKIT
     KINRLTLNDI IDDLSVGSII SPKHITAEYI LQYVRSLSNS YGSNVEALYR LMDNQVEALE
     FHVAENSAVT DIPLIDLELK QNLLICCIVR GNQIITPSGR DTIQLDDTVI VVTTHKGLQD
     ISDILKNAGR
//