ID R7T8Z6_CAPTE Unreviewed; 967 AA.
AC R7T8Z6;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE RecName: Full=G-protein coupled receptors family 3 profile domain-containing protein {ECO:0000259|PROSITE:PS50259};
GN ORFNames=CAPTEDRAFT_222380 {ECO:0000313|EMBL:ELT87875.1};
OS Capitella teleta (Polychaete worm).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Annelida; Polychaeta;
OC Sedentaria; Scolecida; Capitellidae; Capitella.
OX NCBI_TaxID=283909 {ECO:0000313|EMBL:ELT87875.1};
RN [1] {ECO:0000313|Proteomes:UP000014760}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=I ESC-2004 {ECO:0000313|Proteomes:UP000014760};
RA Hellsten U., Grimwood J., Chapman J.A., Shapiro H., Aerts A., Otillar R.P.,
RA Terry A.Y., Boore J.L., Simakov O., Marletaz F., Cho S.-J.,
RA Edsinger-Gonzales E., Havlak P., Kuo D.-H., Larsson T., Lv J., Arendt D.,
RA Savage R., Osoegawa K., de Jong P., Lindberg D.R., Seaver E.C.,
RA Weisblat D.A., Putnam N.H., Grigoriev I.V., Rokhsar D.S.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ELT87875.1, ECO:0000313|Proteomes:UP000014760}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=I ESC-2004 {ECO:0000313|EMBL:ELT87875.1,
RC ECO:0000313|Proteomes:UP000014760};
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
RN [3] {ECO:0000313|EnsemblMetazoa:CapteP222380}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; AMQN01003541; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KB312101; ELT87875.1; -; Genomic_DNA.
DR AlphaFoldDB; R7T8Z6; -.
DR STRING; 283909.R7T8Z6; -.
DR EnsemblMetazoa; CapteT222380; CapteP222380; CapteG222380.
DR HOGENOM; CLU_005240_3_1_1; -.
DR OMA; DACTNVN; -.
DR Proteomes; UP000014760; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004965; F:G protein-coupled GABA receptor activity; IEA:InterPro.
DR CDD; cd15294; 7tmC_GABA-B-R2; 1.
DR CDD; cd06366; PBP1_GABAb_receptor; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR002455; GPCR3_GABA-B.
DR InterPro; IPR000337; GPCR_3.
DR InterPro; IPR017978; GPCR_3_C.
DR InterPro; IPR017979; GPCR_3_CS.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR10519; GABA-B RECEPTOR; 1.
DR PANTHER; PTHR10519:SF20; GAMMA-AMINOBUTYRIC ACID TYPE B RECEPTOR SUBUNIT 2; 1.
DR Pfam; PF00003; 7tm_3; 1.
DR Pfam; PF01094; ANF_receptor; 1.
DR PRINTS; PR01177; GABAB1RECPTR.
DR PRINTS; PR01176; GABABRECEPTR.
DR PRINTS; PR00248; GPCRMGR.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00981; G_PROTEIN_RECEP_F3_3; 1.
DR PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000014760};
KW Transducer {ECO:0000256|ARBA:ARBA00023224};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 360..383
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 403..426
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 438..457
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 478..499
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 534..557
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 577..594
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 600..622
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 369..633
FT /note="G-protein coupled receptors family 3 profile"
FT /evidence="ECO:0000259|PROSITE:PS50259"
FT REGION 903..952
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 660..691
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 967 AA; 108841 MW; 9E7BCB1C5360336E CRC64;
MAVGTKLFFD MMHEPPAKVM LFGDACSEVT TPIAESAKWW NIWQLSYGDT DPLLSNRKTY
PNFFRTVPSD CDHIPARLAI LKAFDWSHVG TIFQDASWGS TRHSYAHGVM AALFDQHDIH
MNTESFSADP LQALKRMKDK DSRIIIGNFD ESMAKKVFCA AHAEDMYGPR YQWVIPGDYS
ENWWRSAVEC SQKHLEEVLE GHFATDVLGL STDGVRTIGG RTAEEYHQLY EDTRKRANAP
YSKFHGYAYD GIWVIARAID SLVRQNQGRF DLEDFRNDRL HATLNDTNFV GVTGPVLFSN
GDRIGGIVIK QFQGGQMVKV GEFDSQKLDF TKGEAIVWKG SGQPPQDKTT TVHELQKVNL
TIYVVMCSFS GLGIIIALTF LAINIRFRRH RYIKMSSPNM NNLIIMGCVF AYTSVFLLGA
DGGLVPPHHY AILCSGRTWI MCVGFTLSFG AMFSKTWRVH AIFTNIKLNK KVIKDYKLFL
LVAFLLFIDI VILSAWQIFD PPERETKNLR ARIDPREMDV EILPVMEFCI SRHMTIWLIS
IYVYKGLLLV FGCFLAWETR QVSIAALNDS KYIGMSVYNV VIMCVSGVPV TFIIKDRPDA
AYLIIALFIT FSTTITLCLV FMPKIVQLKR DPNGEEKRIR ATLRKTMLRH DDSSEMAAKI
TQLSQENSRF KQILENKKLE LQELLLQLGE NALINPETFV HSDPVIFGKN PQRNSSHARI
EPFVADCFIA DSLCSGDPSL DSSSNTWLND KPNTWSLDPN HRGPQQARSM DWIELAKMQD
GKPTWHDGHR AVSGPISHTR AKKKHRVGFD IEAEDSSASE ALLTHNGTPP TYEEAVAASS
LAPAAMFSTG ARTPSYQGLK FLNDIFSLKE TAILSDSDPE KSASPSIQSL PGMHLPAIAI
EKRRRQPERL LDVPSRGLRS TKTSSPSRIH PKRRVAAGRF QESFPQSAGS LPSTPVDVHA
CDVLQYI
//
