ID R7TK97_CAPTE Unreviewed; 488 AA.
AC R7TK97;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=A to I editase domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=CAPTEDRAFT_183692 {ECO:0000313|EMBL:ELT91961.1};
OS Capitella teleta (Polychaete worm).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Annelida; Polychaeta;
OC Sedentaria; Scolecida; Capitellidae; Capitella.
OX NCBI_TaxID=283909 {ECO:0000313|EMBL:ELT91961.1};
RN [1] {ECO:0000313|Proteomes:UP000014760}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=I ESC-2004 {ECO:0000313|Proteomes:UP000014760};
RA Hellsten U., Grimwood J., Chapman J.A., Shapiro H., Aerts A., Otillar R.P.,
RA Terry A.Y., Boore J.L., Simakov O., Marletaz F., Cho S.-J.,
RA Edsinger-Gonzales E., Havlak P., Kuo D.-H., Larsson T., Lv J., Arendt D.,
RA Savage R., Osoegawa K., de Jong P., Lindberg D.R., Seaver E.C.,
RA Weisblat D.A., Putnam N.H., Grigoriev I.V., Rokhsar D.S.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ELT91961.1, ECO:0000313|Proteomes:UP000014760}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=I ESC-2004 {ECO:0000313|EMBL:ELT91961.1,
RC ECO:0000313|Proteomes:UP000014760};
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
RN [3] {ECO:0000313|EnsemblMetazoa:CapteP183692}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AMQN01000373; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KB310317; ELT91961.1; -; Genomic_DNA.
DR AlphaFoldDB; R7TK97; -.
DR STRING; 283909.R7TK97; -.
DR EnsemblMetazoa; CapteT183692; CapteP183692; CapteG183692.
DR HOGENOM; CLU_005382_3_0_1; -.
DR OMA; AKNFYFK; -.
DR Proteomes; UP000014760; Unassembled WGS sequence.
DR GO; GO:0004000; F:adenosine deaminase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR CDD; cd19902; DSRM_DRADA; 1.
DR Gene3D; 3.30.160.20; -; 1.
DR InterPro; IPR002466; A_deamin.
DR InterPro; IPR014720; dsRBD_dom.
DR PANTHER; PTHR10910:SF145; DEAMINASE ACTING ON RNA (ADAR)-1, PUTATIVE-RELATED; 1.
DR PANTHER; PTHR10910; EUKARYOTE SPECIFIC DSRNA BINDING PROTEIN; 1.
DR Pfam; PF02137; A_deamin; 1.
DR Pfam; PF00035; dsrm; 1.
DR SMART; SM00552; ADEAMc; 1.
DR SMART; SM00358; DSRM; 1.
DR SUPFAM; SSF54768; dsRNA-binding domain-like; 1.
DR PROSITE; PS50141; A_DEAMIN_EDITASE; 1.
DR PROSITE; PS50137; DS_RBD; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000014760};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00266}.
FT DOMAIN 15..83
FT /note="DRBM"
FT /evidence="ECO:0000259|PROSITE:PS50137"
FT DOMAIN 154..487
FT /note="A to I editase"
FT /evidence="ECO:0000259|PROSITE:PS50141"
SQ SEQUENCE 488 AA; 53943 MW; FA70CD5902E4F9D5 CRC64;
MPELSSEMFA AIDKNPISAL MEFAQSRKMT ATIECIGQYG PPHQPTFELA AVMGDRTFPY
VQCSNKKDGR KEAAEIALRQ LMAEGTYQAQ NTSELTFDIS SLSADSSHFD RIAALAHQEF
NRVAVTVQES MGGRKILAAL ILKENADDNG KVICIGTGNR CITGTYMSLE GATVNDCHAE
VITRRCFMRF LYHQLLNYSR GDTILCPGSG NRLRIKDQCS LHLYISTAPC GDGALFSPRD
SNTQSSEPVQ NSVHKPTFTS KVQGILRTKV ESGEGTIPIE EDFVSPTWDG ILRGERLRTM
SCSDKVCRWN VLGMQGALLS HFIEPVYLSS ITLGLLYDHG HLSRAVCCRL SHGASMPLLP
PGYHINHPLL GGVTAFTPPR ETQKTKEFSM NWCLNDSQGE LLDGTKGVCS TSDNKKATSR
VSKVALYDLF KETCKHFKRE DLLNASSYHD AKLKASEFQA AKKSMLKKLA ASGYGSWVKK
PTEEEMFF
//
