ID R7U372_CAPTE Unreviewed; 847 AA.
AC R7U372;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 13-SEP-2023, entry version 43.
DE RecName: Full=Bromo domain-containing protein {ECO:0000259|PROSITE:PS50014};
GN ORFNames=CAPTEDRAFT_227094 {ECO:0000313|EMBL:ELU00556.1};
OS Capitella teleta (Polychaete worm).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Annelida; Polychaeta;
OC Sedentaria; Scolecida; Capitellidae; Capitella.
OX NCBI_TaxID=283909 {ECO:0000313|EMBL:ELU00556.1};
RN [1] {ECO:0000313|Proteomes:UP000014760}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=I ESC-2004 {ECO:0000313|Proteomes:UP000014760};
RA Hellsten U., Grimwood J., Chapman J.A., Shapiro H., Aerts A., Otillar R.P.,
RA Terry A.Y., Boore J.L., Simakov O., Marletaz F., Cho S.-J.,
RA Edsinger-Gonzales E., Havlak P., Kuo D.-H., Larsson T., Lv J., Arendt D.,
RA Savage R., Osoegawa K., de Jong P., Lindberg D.R., Seaver E.C.,
RA Weisblat D.A., Putnam N.H., Grigoriev I.V., Rokhsar D.S.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ELU00556.1, ECO:0000313|Proteomes:UP000014760}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=I ESC-2004 {ECO:0000313|EMBL:ELU00556.1,
RC ECO:0000313|Proteomes:UP000014760};
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
RN [3] {ECO:0000313|EnsemblMetazoa:CapteP227094}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AMQN01009657; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KB305899; ELU00556.1; -; Genomic_DNA.
DR AlphaFoldDB; R7U372; -.
DR STRING; 283909.R7U372; -.
DR EnsemblMetazoa; CapteT227094; CapteP227094; CapteG227094.
DR HOGENOM; CLU_007253_1_0_1; -.
DR OMA; AYKPHTT; -.
DR Proteomes; UP000014760; Unassembled WGS sequence.
DR CDD; cd05507; Bromo_brd8_like; 1.
DR Gene3D; 1.20.920.10; Bromodomain-like; 1.
DR InterPro; IPR037966; Brd8_Bromo_dom.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR PANTHER; PTHR15398; BROMODOMAIN-CONTAINING PROTEIN 8; 1.
DR PANTHER; PTHR15398:SF4; BROMODOMAIN-CONTAINING PROTEIN 8; 1.
DR Pfam; PF00439; Bromodomain; 1.
DR PRINTS; PR00503; BROMODOMAIN.
DR SMART; SM00297; BROMO; 1.
DR SUPFAM; SSF47370; Bromodomain; 1.
DR PROSITE; PS50014; BROMODOMAIN_2; 1.
PE 4: Predicted;
KW Bromodomain {ECO:0000256|PROSITE-ProRule:PRU00035};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000014760}.
FT DOMAIN 705..775
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT REGION 1..159
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 295..335
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 525..685
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 807..847
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 239..266
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 74..141
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 550..566
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 608..623
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 624..642
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 663..681
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 807..831
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 847 AA; 93497 MW; 7E7009D34123D15A CRC64;
MYPAHGPYGH KAKKHKHRNR SSSSSSSSSS SSSDDEKKRW KKEQKRQKKL MKKMAKKGQL
PPGAGCAYPG YPSGAPHPGY PGYPGQPTNC PGAPPAYPQG SVPPPAYPQG NIPPPAYPQG
NVPPPYPQGS APQPAHPQAP QYPPQQGAEN RLGKQKPTDV WTLREKLALS CGVMRSGDLN
WVSVSRSAKQ FAEPGRPAEW FSHKNCALQY SELRDNVETP KRKRGEREVL EAPGDIIVRK
MTIDRIEELK KTIQEQQHRF KKLKRETELV QSGQADEKLK EIWAEIQKKI AADASKNAAA
SSAPVTAPVA TAASEPVTPE PSKSPSLKAK KASPGLKLNI EEAQLAQKME FEASTPVAST
SDVCTTPLIT TPKEEEEEPV VKQERPASPL LCSLLKNQGT LHDALQKQEQ RSAKIIEEVQ
KQEINSSGIH IVKVVDGNSA VIEQHVEQVK VEDKTEVCDC NQEVIETEVV ATDDAVIEVK
EEIVVDDPEP TIEVKEEVKE EIQGCEDMIQ KSEKKEEAVN CREKVLKPTS TNEASPGPPP
PVPRQARTPS ASAKDKKLKY YEQEAPETPD PDQSFGSRMS GEFEEMAGSP ASSVISNETD
SGSVKGKARR SRGGKARTGG RKSQRITRIK EEEKKESKTS EAETSEDDDE GSEDPLNSGG
IKQALSGLES VPNSPASVTL GSDTEDEKAH RIWKKSILLV WSSAAHHKYA NVFRHPVTED
IAPGYKSCVH RPMDLSTIKR NIDMGIIRTT AEFQRDMMLM FSNAIMYNNS DHHVFRMATQ
MYDDVMVHIE QFVNTELMVQ TEPKILRASR RSETVHSDKE DDSKKKKSSS VEQEQLAPGG
KAKKRRA
//
