ID R7VHP0_CAPTE Unreviewed; 293 AA.
AC R7VHP0;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=Sulfotransferase domain-containing protein {ECO:0000259|Pfam:PF00685};
GN ORFNames=CAPTEDRAFT_142623 {ECO:0000313|EMBL:ELU15816.1};
OS Capitella teleta (Polychaete worm).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Annelida; Polychaeta;
OC Sedentaria; Scolecida; Capitellidae; Capitella.
OX NCBI_TaxID=283909 {ECO:0000313|EMBL:ELU15816.1};
RN [1] {ECO:0000313|Proteomes:UP000014760}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=I ESC-2004 {ECO:0000313|Proteomes:UP000014760};
RA Hellsten U., Grimwood J., Chapman J.A., Shapiro H., Aerts A., Otillar R.P.,
RA Terry A.Y., Boore J.L., Simakov O., Marletaz F., Cho S.-J.,
RA Edsinger-Gonzales E., Havlak P., Kuo D.-H., Larsson T., Lv J., Arendt D.,
RA Savage R., Osoegawa K., de Jong P., Lindberg D.R., Seaver E.C.,
RA Weisblat D.A., Putnam N.H., Grigoriev I.V., Rokhsar D.S.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ELU15816.1, ECO:0000313|Proteomes:UP000014760}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=I ESC-2004 {ECO:0000313|EMBL:ELU15816.1,
RC ECO:0000313|Proteomes:UP000014760};
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
RN [3] {ECO:0000313|EnsemblMetazoa:CapteP142623}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
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DR EMBL; AMQN01004461; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KB293569; ELU15816.1; -; Genomic_DNA.
DR AlphaFoldDB; R7VHP0; -.
DR STRING; 283909.R7VHP0; -.
DR EnsemblMetazoa; CapteT142623; CapteP142623; CapteG142623.
DR HOGENOM; CLU_017703_0_0_1; -.
DR Proteomes; UP000014760; Unassembled WGS sequence.
DR GO; GO:0008146; F:sulfotransferase activity; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR037359; NST/OST.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000863; Sulfotransferase_dom.
DR PANTHER; PTHR10605:SF65; HEPARAN SULFATE GLUCOSAMINE 3-O-SULFOTRANSFERASE 6; 1.
DR PANTHER; PTHR10605; HEPARAN SULFATE SULFOTRANSFERASE; 1.
DR Pfam; PF00685; Sulfotransfer_1; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|PIRSR:PIRSR637359-3};
KW Reference proteome {ECO:0000313|Proteomes:UP000014760}.
FT DOMAIN 41..249
FT /note="Sulfotransferase"
FT /evidence="ECO:0000259|Pfam:PF00685"
FT ACT_SITE 50
FT /note="For sulfotransferase activity"
FT /evidence="ECO:0000256|PIRSR:PIRSR637359-1"
FT BINDING 133
FT /ligand="3'-phosphoadenylyl sulfate"
FT /ligand_id="ChEBI:CHEBI:58339"
FT /evidence="ECO:0000256|PIRSR:PIRSR637359-2"
FT BINDING 141
FT /ligand="3'-phosphoadenylyl sulfate"
FT /ligand_id="ChEBI:CHEBI:58339"
FT /evidence="ECO:0000256|PIRSR:PIRSR637359-2"
FT BINDING 245
FT /ligand="3'-phosphoadenylyl sulfate"
FT /ligand_id="ChEBI:CHEBI:58339"
FT /evidence="ECO:0000256|PIRSR:PIRSR637359-2"
FT DISULFID 246..252
FT /evidence="ECO:0000256|PIRSR:PIRSR637359-3"
SQ SEQUENCE 293 AA; 34569 MW; F08AF20F6479DFDE CRC64;
MSEELNGSDP SELVDEWFKE RKFAELKAIP EDIEGRKPRL PQCILIGERK TGTTALLHFL
VRHPQIKAPR KEIHFFDQNA NFREGQLWYV NKMPTTNSTE VTFEKTPSYF RSSWTPERMH
KMIPDVKLML SLRDPIQRAI SDFHFSIEAN WSCDFDKTLH SSFDGYALND GKINMDFPPI
ARSIYALSLE NWFKYFDRKQ FFIYDGDSFV HENPAKLLQK IEKFIGLEPY FTLKMFSYSK
TRGFWCLKDP GCISFGGRPH ADLEAVTRQK IKRFFHPYNQ KLYDMVSHDF GWS
//
