ID R7WL36_9NOCA Unreviewed; 605 AA.
AC R7WL36;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Penicillin-binding protein {ECO:0000313|EMBL:EOM76012.1};
GN ORFNames=Rrhod_2660 {ECO:0000313|EMBL:EOM76012.1};
OS Rhodococcus rhodnii LMG 5362.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Rhodococcus.
OX NCBI_TaxID=1273125 {ECO:0000313|EMBL:EOM76012.1, ECO:0000313|Proteomes:UP000013525};
RN [1] {ECO:0000313|EMBL:EOM76012.1, ECO:0000313|Proteomes:UP000013525}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LMG 5362 {ECO:0000313|EMBL:EOM76012.1,
RC ECO:0000313|Proteomes:UP000013525};
RX PubMed=23788540;
RA Pachebat J.A., van Keulen G., Whitten M.M., Girdwood S., Del Sol R.,
RA Dyson P.J., Facey P.D.;
RT "Draft Genome Sequence of Rhodococcus rhodnii Strain LMG5362, a Symbiont of
RT Rhodnius prolixus (Hemiptera, Reduviidae, Triatominae), the Principle
RT Vector of Trypanosoma cruzi.";
RL Genome Announc. 1:e00329-13(2013).
CC -!- SIMILARITY: Belongs to the transpeptidase family.
CC {ECO:0000256|ARBA:ARBA00007171}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EOM76012.1}.
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DR EMBL; APMY01000077; EOM76012.1; -; Genomic_DNA.
DR AlphaFoldDB; R7WL36; -.
DR PATRIC; fig|1273125.3.peg.2542; -.
DR eggNOG; COG0768; Bacteria.
DR OrthoDB; 5241017at2; -.
DR Proteomes; UP000013525; Unassembled WGS sequence.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR GO; GO:0046677; P:response to antibiotic; IEA:InterPro.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR007887; MecA_N.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF24; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE PBPA; 1.
DR Pfam; PF05223; MecA_N; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000013525};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..30
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 31..605
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5039338788"
FT DOMAIN 38..145
FT /note="NTF2-like N-terminal transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF05223"
FT DOMAIN 330..585
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 605 AA; 62600 MW; 651BC0393C5FB35F CRC64;
MTGPVDDVSR GVRRALALAV AVCAAATVTA CSPGADGPTA AAQRFLDAVA AGDTAGAAAL
SDRPDDARGA LDSAWSSLQA ETLVATAGES RGSGDTATVE YTYEWHLPKD RVWTYTGEMR
MARSGGDWQV RWSATDLHPR LGDTQRMELR ATTPPRARVN ERSGSDVLVP GIVHRIRFDA
SAADDVVASA RALTDALRPF EPDLTVQGLV ESATGTGGDY LVMRLRDDDY ATVEGVLAAI
PGVSVGDEAD LVSTDRAFAP DLVDQVKKAV VDEVDGTAGW SVVTVNRNGA DVGVLTETPP
EPAPSFSISL DRRVQIAAQA AVDARVEQAM TVVVQPSTGD VLAVAQNEAA DRDGPVATTG
LYPPGSTFKM ITAAAAMESG LAGPDSPVPC PGSIVIGERS VPNYNGFSLG TVPMATAFAR
SCNTTFAKLA SEMAADDLTR AAAQFGIGPE YDVVGVPVSA GSVPPAPDLV QRTEDGFGQG
RVLVSPMGMA MAAATVAHGS APTPRLLVGA ETAVAGERPP VDPETIEGLR AMMRLVVTSG
TADRIADQGE VYGKTGEAEV EGGSHAWFVG YRGDLAFATL VVRGGSSDNA VAVTRQMFDG
LPPDY
//
