ID R7XVY6_9ACTN Unreviewed; 337 AA.
AC R7XVY6;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=Sigma-70 region 3 domain-containing protein {ECO:0000313|EMBL:EON23499.1};
GN ORFNames=CF8_2535 {ECO:0000313|EMBL:EON23499.1};
OS Nocardioides sp. CF8.
OC Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC Nocardioidaceae; Nocardioides.
OX NCBI_TaxID=110319 {ECO:0000313|EMBL:EON23499.1, ECO:0000313|Proteomes:UP000015971};
RN [1] {ECO:0000313|EMBL:EON23499.1, ECO:0000313|Proteomes:UP000015971}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CF8 {ECO:0000313|EMBL:EON23499.1,
RC ECO:0000313|Proteomes:UP000015971};
RX PubMed=23833136;
RA Kimbrel J.A., Chang J., Arp D.J., Sayavedra-Soto L.A.;
RT "The Draft Genome Sequence of Nocardioides sp. Strain CF8 Reveals the Scope
RT of Its Metabolic Capabilities.";
RL Genome Announc. 1:e00439-e00439(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EON23499.1}.
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DR EMBL; ASEP01000080; EON23499.1; -; Genomic_DNA.
DR AlphaFoldDB; R7XVY6; -.
DR STRING; 110319.CF8_2535; -.
DR PATRIC; fig|110319.3.peg.3209; -.
DR eggNOG; COG0568; Bacteria.
DR HOGENOM; CLU_014793_3_4_11; -.
DR OrthoDB; 9809557at2; -.
DR Proteomes; UP000015971; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0016987; F:sigma factor activity; IEA:UniProtKB-KW.
DR GO; GO:0006352; P:DNA-templated transcription initiation; IEA:InterPro.
DR CDD; cd06171; Sigma70_r4; 1.
DR Gene3D; 1.10.601.10; RNA Polymerase Primary Sigma Factor; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR InterPro; IPR014284; RNA_pol_sigma-70_dom.
DR InterPro; IPR000943; RNA_pol_sigma70.
DR InterPro; IPR009042; RNA_pol_sigma70_r1_2.
DR InterPro; IPR007627; RNA_pol_sigma70_r2.
DR InterPro; IPR007624; RNA_pol_sigma70_r3.
DR InterPro; IPR007630; RNA_pol_sigma70_r4.
DR InterPro; IPR013325; RNA_pol_sigma_r2.
DR InterPro; IPR013324; RNA_pol_sigma_r3/r4-like.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR NCBIfam; TIGR02937; sigma70-ECF; 1.
DR PANTHER; PTHR30603; RNA POLYMERASE SIGMA FACTOR RPO; 1.
DR PANTHER; PTHR30603:SF47; RNA POLYMERASE SIGMA FACTOR SIGF, CHLOROPLASTIC; 1.
DR Pfam; PF00140; Sigma70_r1_2; 1.
DR Pfam; PF04542; Sigma70_r2; 1.
DR Pfam; PF04539; Sigma70_r3; 1.
DR Pfam; PF04545; Sigma70_r4; 1.
DR PRINTS; PR00046; SIGMA70FCT.
DR SUPFAM; SSF88946; Sigma2 domain of RNA polymerase sigma factors; 1.
DR SUPFAM; SSF88659; Sigma3 and sigma4 domains of RNA polymerase sigma factors; 2.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000015971};
KW Sigma factor {ECO:0000256|ARBA:ARBA00023082};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 31..63
FT /note="RNA polymerase sigma-70 region 1.2"
FT /evidence="ECO:0000259|Pfam:PF00140"
FT DOMAIN 104..172
FT /note="RNA polymerase sigma-70 region 2"
FT /evidence="ECO:0000259|Pfam:PF04542"
FT DOMAIN 182..256
FT /note="RNA polymerase sigma-70 region 3"
FT /evidence="ECO:0000259|Pfam:PF04539"
FT DOMAIN 273..324
FT /note="RNA polymerase sigma-70 region 4"
FT /evidence="ECO:0000259|Pfam:PF04545"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 337 AA; 37394 MW; 5574F8C51F1ECA5D CRC64;
MTTTQITKNA PARSAAGRGT RGATREIEGR DSVGLYLDEI ARTPLLDAIT EVELSKTIEA
GLLAEKLLEE GRVGRKKGGA PGRATEEELE WLAEEGRKAV DQFISANLRL VVSIARKYGR
SQMPMLDLIQ EGNTGLIRAV EKFDYSKGYK FSTYATWWVR QAITRGIAQQ ARVVRLPVHV
VEELNQVSGA RRTLERQLGR DPEPHEIATE LDMDVDRVLD LMSWGRDHVS LDTPVDEDGD
TSLGDLMAQE TAPGPDLEFL DVEARQRLED LVSHLDERAA DIIRARYGLN DGRQHKLADI
GAKHGISAER VRQLEREALQ KLRRIGDPDL ATGSTAA
//
