ID R7Y1Z2_9ACTN Unreviewed; 401 AA.
AC R7Y1Z2;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Threonine synthase {ECO:0000313|EMBL:EON25260.1};
GN ORFNames=CF8_0611 {ECO:0000313|EMBL:EON25260.1};
OS Nocardioides sp. CF8.
OC Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC Nocardioidaceae; Nocardioides.
OX NCBI_TaxID=110319 {ECO:0000313|EMBL:EON25260.1, ECO:0000313|Proteomes:UP000015971};
RN [1] {ECO:0000313|EMBL:EON25260.1, ECO:0000313|Proteomes:UP000015971}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CF8 {ECO:0000313|EMBL:EON25260.1,
RC ECO:0000313|Proteomes:UP000015971};
RX PubMed=23833136;
RA Kimbrel J.A., Chang J., Arp D.J., Sayavedra-Soto L.A.;
RT "The Draft Genome Sequence of Nocardioides sp. Strain CF8 Reveals the Scope
RT of Its Metabolic Capabilities.";
RL Genome Announc. 1:e00439-e00439(2013).
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933,
CC ECO:0000256|PIRSR:PIRSR604450-51};
CC -!- SIMILARITY: Belongs to the threonine synthase family.
CC {ECO:0000256|ARBA:ARBA00005517}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EON25260.1}.
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DR EMBL; ASEP01000024; EON25260.1; -; Genomic_DNA.
DR AlphaFoldDB; R7Y1Z2; -.
DR STRING; 110319.CF8_0611; -.
DR PATRIC; fig|110319.3.peg.1195; -.
DR eggNOG; COG0498; Bacteria.
DR HOGENOM; CLU_028142_4_1_11; -.
DR Proteomes; UP000015971; Chromosome.
DR GO; GO:1901605; P:alpha-amino acid metabolic process; IEA:UniProt.
DR CDD; cd01563; Thr-synth_1; 1.
DR Gene3D; 3.40.50.1100; -; 2.
DR InterPro; IPR004450; Thr_synthase-like.
DR InterPro; IPR001926; TrpB-like_PALP.
DR InterPro; IPR036052; TrpB-like_PALP_sf.
DR NCBIfam; TIGR00260; thrC; 1.
DR PANTHER; PTHR48078:SF6; ACT DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR48078; THREONINE DEHYDRATASE, MITOCHONDRIAL-RELATED; 1.
DR Pfam; PF00291; PALP; 1.
DR SUPFAM; SSF53686; Tryptophan synthase beta subunit-like PLP-dependent enzymes; 1.
PE 3: Inferred from homology;
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW ECO:0000256|PIRSR:PIRSR604450-51};
KW Reference proteome {ECO:0000313|Proteomes:UP000015971}.
FT DOMAIN 68..369
FT /note="Tryptophan synthase beta chain-like PALP"
FT /evidence="ECO:0000259|Pfam:PF00291"
FT MOD_RES 102
FT /note="N6-(pyridoxal phosphate)lysine"
FT /evidence="ECO:0000256|PIRSR:PIRSR604450-51"
SQ SEQUENCE 401 AA; 42853 MW; 99BF101FBF57BC08 CRC64;
MLVCRECSHE VELGPHYACP ECFGPLEVAY DFPVVTREEI AAGPANIWRY KALLPVPSDI
EQSPNMEPGF TRLLKAHNLG RELGIDNLWV KDDSTNPTNS FKDRVVACAL SAARELDAKV
FACPSTGNLA NAVAAAGARA GIKTVVFIPS NLEQPKQVNS AIFTDRLVAV NGNYDDVNKL
ASEIAGEEEG WAFVNVNVRP FYAEGSKTLG YEIAEQLGWR LPDQIVIPVA SGSQLTKVDK
SFQELIKLGL VEDKPYKVFG AQATGCSPVS VAYKANTDAI RPVKPDTIAK SLAIGNPADG
IYVLDVCRRT GGAVEDITDD EVREGIVLLA RTEGIFTETA GGTTVGVLKK LVETGQLDTS
LETVVINTGH GLKTLDAISD QVGAAATIEP TYSAFTAANL V
//
