ID R7Y3J9_9ACTN Unreviewed; 486 AA.
AC R7Y3J9;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Peptidoglycan glycosyltransferase {ECO:0000313|EMBL:EON25815.1};
GN ORFNames=CF8_0016 {ECO:0000313|EMBL:EON25815.1};
OS Nocardioides sp. CF8.
OC Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC Nocardioidaceae; Nocardioides.
OX NCBI_TaxID=110319 {ECO:0000313|EMBL:EON25815.1, ECO:0000313|Proteomes:UP000015971};
RN [1] {ECO:0000313|EMBL:EON25815.1, ECO:0000313|Proteomes:UP000015971}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CF8 {ECO:0000313|EMBL:EON25815.1,
RC ECO:0000313|Proteomes:UP000015971};
RX PubMed=23833136;
RA Kimbrel J.A., Chang J., Arp D.J., Sayavedra-Soto L.A.;
RT "The Draft Genome Sequence of Nocardioides sp. Strain CF8 Reveals the Scope
RT of Its Metabolic Capabilities.";
RL Genome Announc. 1:e00439-e00439(2013).
CC -!- SIMILARITY: Belongs to the transpeptidase family.
CC {ECO:0000256|ARBA:ARBA00007171}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EON25815.1}.
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DR EMBL; ASEP01000002; EON25815.1; -; Genomic_DNA.
DR RefSeq; WP_010831111.1; NZ_CM001852.1.
DR AlphaFoldDB; R7Y3J9; -.
DR STRING; 110319.CF8_0016; -.
DR PATRIC; fig|110319.3.peg.972; -.
DR eggNOG; COG0768; Bacteria.
DR HOGENOM; CLU_009289_1_0_11; -.
DR OrthoDB; 9766847at2; -.
DR Proteomes; UP000015971; Chromosome.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF24; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE PBPA; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000015971};
KW Transferase {ECO:0000313|EMBL:EON25815.1}.
FT DOMAIN 158..481
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 486 AA; 51083 MW; 007CF575F672B07A CRC64;
MNKPIRTISM FCLLLFAALL LNSTYLMYVR ADDLAEDPRN RRVITAAFAR ERGAILVGKE
TVARSVEVDD KYKFQRTYAQ PFKYAPITGY FSYYSQTGIE RSQNDVLSGD DSRLFVTRLV
DMLSNTEPQG GNVELTINAA AQDAAWDGLQ ALPGDAKGAV VALEPSTGKV LAMVSSPTFD
PNLLASHDLS DVEDASDQLQ DDPANPLINR AIGTTLPPGS TFKLITAAAA IESGNYDQDS
LVPGGAKFQL PQSTTKVGNW QGGSCGGNKI TLTQALAVSC NVSFLTLANE LGTEAMTEQA
EAFGFNSTSL EDLPGQASSL YPADMDAPQT ALSGIGQSSV TATPLQMAMV AAGIANGGEV
KRPYLVDEVR APNASLLDKT EESTYSRAIS STTADQLTDM MVATVDDGTA GIAAIPGVRV
AGKTGTAQST DSRPPYAWFV SFAPADDPQV AVAVMVEASD TAREEIAGGS LGGPIAKAIM
QAVMGS
//
