ID R7YQR9_CONA1 Unreviewed; 985 AA.
AC R7YQR9;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=Elongation factor EF-2 {ECO:0000313|EMBL:EON64193.1};
GN ORFNames=W97_03423 {ECO:0000313|EMBL:EON64193.1};
OS Coniosporium apollinis (strain CBS 100218) (Rock-inhabiting black yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetes incertae sedis; Coniosporium.
OX NCBI_TaxID=1168221 {ECO:0000313|EMBL:EON64193.1, ECO:0000313|Proteomes:UP000016924};
RN [1] {ECO:0000313|Proteomes:UP000016924}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 100218 {ECO:0000313|Proteomes:UP000016924};
RG The Broad Institute Genome Sequencing Platform;
RA Cuomo C., Gorbushina A., Noack S., Walker B., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Goldberg J., Griggs A., Gujja S.,
RA Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C., Montmayeur A.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The genome sequence of Coniosporium apollinis CBS 100218.";
RL Submitted (JUN-2012) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; JH767567; EON64193.1; -; Genomic_DNA.
DR RefSeq; XP_007779510.1; XM_007781320.1.
DR AlphaFoldDB; R7YQR9; -.
DR STRING; 1168221.R7YQR9; -.
DR GeneID; 19900734; -.
DR eggNOG; KOG0468; Eukaryota.
DR HOGENOM; CLU_002794_11_2_1; -.
DR OMA; YIFRPIR; -.
DR OrthoDB; 166721at2759; -.
DR Proteomes; UP000016924; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR CDD; cd04098; eEF2_C_snRNP; 1.
DR CDD; cd04090; EF2_II_snRNP; 1.
DR CDD; cd01683; EF2_IV_snRNP; 1.
DR CDD; cd16264; snRNP_III; 1.
DR CDD; cd04167; Snu114p; 1.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.30.70.240; -; 1.
DR Gene3D; 3.30.70.870; Elongation Factor G (Translational Gtpase), domain 3; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR Gene3D; 3.90.1430.10; Yeast translation eEF2 (G' domain); 1.
DR InterPro; IPR035647; EFG_III/V.
DR InterPro; IPR000640; EFG_V-like.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR031950; EFTUD2_N.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR044121; Snu114_GTP-bd.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR005517; Transl_elong_EFG/EF2_IV.
DR InterPro; IPR035655; U5-116kDa_C.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR42908:SF6; 116 KDA U5 SMALL NUCLEAR RIBONUCLEOPROTEIN COMPONENT; 1.
DR PANTHER; PTHR42908; TRANSLATION ELONGATION FACTOR-RELATED; 1.
DR Pfam; PF00679; EFG_C; 1.
DR Pfam; PF03764; EFG_IV; 1.
DR Pfam; PF16004; EFTUD2; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SMART; SM00838; EFG_C; 1.
DR SMART; SM00889; EFG_IV; 1.
DR SUPFAM; SSF54980; EF-G C-terminal domain-like; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW Elongation factor {ECO:0000313|EMBL:EON64193.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW mRNA splicing {ECO:0000256|ARBA:ARBA00023187};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Protein biosynthesis {ECO:0000313|EMBL:EON64193.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000016924}.
FT DOMAIN 132..420
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
FT REGION 1..47
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..15
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 985 AA; 109872 MW; 0AAC92B3EF8BEFC5 CRC64;
MDDLYDEFGN FIGEAESEEE SDHGVQAADA YVYDDQPIDE DEEEARDQQL MEVDADGPSN
AVVLHEDKQY YPTAQQVYGP DVETLVQEED TQSLSQPIIA PVVQKKFTVQ EADLPPVFFK
REFMTDLMNL PEQIRNVAVA GHLHHGKTAF MDMLVLETHD IQDRLEKKTG RKRDEQLRYT
DVHVLERERG LSIKASPMSL VLQGTKGKSH LFNIIDTPGH VNFVDEVASS LRLVDGVVLV
VDVVEGVQVN TEQIIKHAIL EDLPLVLVVN KMDRLILELK LPPADAYFKL KHVIEEVNTV
IENTIPGRGE RRRVSPEKGN VAFACTSMGW CFTLQSFAKM YADSYEKVNA DDFALRLWGD
IFFNPRSRKF TRKAMEDGSK RSFVNFVLEP IYKLYSHTIS ESPEDLKDTL ATLGIHLKPS
QYKIDAKDLL KLVCGQFFGP AHGFVDMVVE HIPSPLSGAQ RLLERYYAGP LDTTTATAMS
SCDQDGPLIV HITKLFNTTD AKAFHALGRV MSGTARPGDA VRVLGEGYTL EDEEDMVSAV
IDNTFIGNSR YNIPVSGVPA GNWVLMSGVD NSIVKTATLV APKLPNGEDA YIFRPVKHFF
ESVFKVAVEP INPSELPKML DGLRKINKSY PLVTTKVEES GEHVVLGTGE LYMDCVLHDL
RRLYAEMEIK VSDPVTRFCE TVVETSAIKC YALTPNKKNK LTMVAEPLDP GIAEDIEAGK
VNIKDPVRKV GKFFEENYGY DLLASRNIWA FGPDDMGPNI LQNDTLPSDV DQKLLKSVRD
SIKQGFSWAT REGPLCEEPI RNTKFRIMDV SLAPEPILRG GGQIIPTARR AAYSSFLMAS
PRLMEPVYEC SMIGPADAVS SLYTVLARRR GHVLQDGPIA GTPLYSVKGL IPVIDSFGFE
TDLRIHTQGQ ATVSLVFDRW SIVPGDPLDK DIKLRPLEPA SAQATARDFV LKTRRRKGLA
EDVTISKFLE PELFRSLKES GILDG
//
