ID R7YTP5_CONA1 Unreviewed; 1305 AA.
AC R7YTP5;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=REM-1 domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=W97_04535 {ECO:0000313|EMBL:EON65297.1};
OS Coniosporium apollinis (strain CBS 100218) (Rock-inhabiting black yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetes incertae sedis; Coniosporium.
OX NCBI_TaxID=1168221 {ECO:0000313|EMBL:EON65297.1, ECO:0000313|Proteomes:UP000016924};
RN [1] {ECO:0000313|Proteomes:UP000016924}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 100218 {ECO:0000313|Proteomes:UP000016924};
RG The Broad Institute Genome Sequencing Platform;
RA Cuomo C., Gorbushina A., Noack S., Walker B., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Goldberg J., Griggs A., Gujja S.,
RA Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C., Montmayeur A.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The genome sequence of Coniosporium apollinis CBS 100218.";
RL Submitted (JUN-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the RICTOR family.
CC {ECO:0000256|ARBA:ARBA00008878}.
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DR EMBL; JH767573; EON65297.1; -; Genomic_DNA.
DR RefSeq; XP_007780614.1; XM_007782424.1.
DR STRING; 1168221.R7YTP5; -.
DR GeneID; 19901846; -.
DR eggNOG; KOG3694; Eukaryota.
DR HOGENOM; CLU_001013_1_1_1; -.
DR OMA; EIRIHAT; -.
DR OrthoDB; 90320at2759; -.
DR Proteomes; UP000016924; Unassembled WGS sequence.
DR GO; GO:0031932; C:TORC2 complex; IEA:InterPro.
DR GO; GO:0031929; P:TOR signaling; IEA:InterPro.
DR Gene3D; 1.10.287.160; HR1 repeat; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR011072; HR1_rho-bd.
DR InterPro; IPR036274; HR1_rpt_sf.
DR InterPro; IPR028268; Pianissimo_fam.
DR InterPro; IPR028267; Pianissimo_N.
DR InterPro; IPR029453; Rictor_IV.
DR InterPro; IPR029451; RICTOR_M.
DR InterPro; IPR029452; RICTOR_V.
DR PANTHER; PTHR13298; CYTOSOLIC REGULATOR PIANISSIMO; 1.
DR PANTHER; PTHR13298:SF11; RAPAMYCIN-INSENSITIVE COMPANION OF MTOR; 1.
DR Pfam; PF02185; HR1; 1.
DR Pfam; PF14663; RasGEF_N_2; 1.
DR Pfam; PF14666; RICTOR_M; 1.
DR Pfam; PF14664; RICTOR_N; 1.
DR Pfam; PF14668; RICTOR_V; 1.
DR SMART; SM01303; RasGEF_N_2; 1.
DR SMART; SM01307; RICTOR_M; 1.
DR SMART; SM01308; RICTOR_N; 1.
DR SMART; SM01310; RICTOR_V; 1.
DR SUPFAM; SSF48371; ARM repeat; 2.
DR SUPFAM; SSF46585; HR1 repeat; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000016924}.
FT DOMAIN 215..578
FT /note="Rapamycin-insensitive companion of mTOR N-terminal"
FT /evidence="ECO:0000259|SMART:SM01308"
FT DOMAIN 657..881
FT /note="Rapamycin-insensitive companion of mTOR middle"
FT /evidence="ECO:0000259|SMART:SM01307"
FT DOMAIN 1069..1141
FT /note="Rapamycin-insensitive companion of mTOR"
FT /evidence="ECO:0000259|SMART:SM01310"
FT REGION 1..93
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 168..192
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 501..520
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 623..652
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1268..1305
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 116..143
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 30..68
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 71..93
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1270..1291
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1305 AA; 146043 MW; 0630AC5D153B25D0 CRC64;
MSSQAETPSA DQNALLPISR VGKDGRSLAT TAFSRGQSYA TTVGPPPGSF SSELRSTTSR
SETPRPDFTA HTSFGEDDTR TTSEQRQAEL RDQIEKETKI KIGSENLLEA LAAKGAKQSK
AQKAIVEAEL NSSNRKLAQL KLDFQAEVQR AKEPPSNAGS RISYLFRNAP SRSTTHQPAS
DDESESEPET ESPTFVLAEI LQALEAEGMQ HDYYVEQANS LVELFKRHPT LKFDLVWSIF
GLRMQTMLLS DNREVVAAGY RVIRYAITDR KSLQTIRALH TDYLVILSLV KEGKASVERE
QALKFVRAFL DVKDGVKEIC QAVIRIVIAV AEHSDDRLRN ICILTLTEIL ARDPARVVAA
GGIGTLTDAL GEGHYHAAES LTGAFLYLLD VPQRRKLLRS GHELEVPFAA FIDIPTSHSH
EEKLKTNAKV IASLLRGWPG LIALSMNNFL PIRSLVSSLY TSIPYVRSIV MELIFDLLRI
KPPSWSSSFL AGRRLTTYGR VTNMKSETPA QPTSESPDEK DKRSLVDHYA AILLAVLLHS
GLLEALLHAE EDPLTEPLKR KTTLLLGEIL KMASELLPTS WSSDLQVLPG LLKSASSFHV
EDRFVATGTI YQVDSINRTL YRSATNPSHA RKPETQSELD DNTRQADQPK TQANVQMGEA
AFRQQLVDTG TLRSSNFTKW DWTLIQQTLD GPMFDPKRLD DAINATDFAK RMFGFYRPFK
HRFSEIKNTR PNQRYVRAGC ALVRGFLANP QGVRYLAENK MIRQLAECLS HFDRMSGLTS
ESPLFTVERM SDTLTGGYFA ILGAMTADPK GLLILERWKV INMFYHIIEL PSRDDLIKAL
LSNMDYTLDG HLRIIVSKAM TSCSKDIRIF STRLLRKYAK KPMQASESAP IGSGVAEWAI
RLLVTQLYDP EIEVCEVAIK ILEEACNQRH SLEYVVKCRP ALDHLGEIGA PLLLRFLSTS
VGYHYLDGLD YITKEMDDWF LGRNDSYVSL VEASLARALA DVPDKPHTQQ LSFDETPDIT
DYGVVPPHFY RELTRTEEGC KLLEQKGHFD EFASTIREFG MEDEDAETII KVKGCLWAVG
NVGSMELGAP FLEKTDVVKW IVDIAEKSEV MTMRGTAVFV LGLISRSLHG QEILIEYGWD
ANYNEMGESV GYCVPLDLRK LFAPWTASTA RPDTVNPATA PKPKITDRDP LNARILKLVT
DLGNTVLAKR AVADLQNIKA RKAPGFQKPS LFHKVMAILE SHHFRLPVCR FVIDLFDKSV
LRQIVLEIEN DSDEEGAEDD DEDEDSDEEE SPILESKALT RPDPE
//
