ID R7Z4D6_CONA1 Unreviewed; 569 AA.
AC R7Z4D6;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=Dimethylaniline monooxygenase {ECO:0008006|Google:ProtNLM};
GN ORFNames=W97_08137 {ECO:0000313|EMBL:EON68879.1};
OS Coniosporium apollinis (strain CBS 100218) (Rock-inhabiting black yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetes incertae sedis; Coniosporium.
OX NCBI_TaxID=1168221 {ECO:0000313|EMBL:EON68879.1, ECO:0000313|Proteomes:UP000016924};
RN [1] {ECO:0000313|Proteomes:UP000016924}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 100218 {ECO:0000313|Proteomes:UP000016924};
RG The Broad Institute Genome Sequencing Platform;
RA Cuomo C., Gorbushina A., Noack S., Walker B., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Goldberg J., Griggs A., Gujja S.,
RA Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C., Montmayeur A.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The genome sequence of Coniosporium apollinis CBS 100218.";
RL Submitted (JUN-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the FMO family. {ECO:0000256|ARBA:ARBA00009183}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JH767602; EON68879.1; -; Genomic_DNA.
DR RefSeq; XP_007784196.1; XM_007786006.1.
DR AlphaFoldDB; R7Z4D6; -.
DR STRING; 1168221.R7Z4D6; -.
DR GeneID; 19905448; -.
DR eggNOG; KOG1399; Eukaryota.
DR HOGENOM; CLU_006909_7_5_1; -.
DR OMA; VIPMIFY; -.
DR OrthoDB; 445965at2759; -.
DR Proteomes; UP000016924; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0004499; F:N,N-dimethylaniline monooxygenase activity; IEA:InterPro.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR000960; Flavin_mOase.
DR InterPro; IPR020946; Flavin_mOase-like.
DR PANTHER; PTHR23023; DIMETHYLANILINE MONOOXYGENASE; 1.
DR PANTHER; PTHR23023:SF304; DIMETHYLANILINE MONOOXYGENASE; 1.
DR Pfam; PF00743; FMO-like; 2.
DR PIRSF; PIRSF000332; FMO; 2.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Monooxygenase {ECO:0000256|ARBA:ARBA00023033};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000016924};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 475..494
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 514..536
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 569 AA; 63868 MW; D35E12CA857A2C24 CRC64;
MASIKVAIIG AGEDEIGGTF KYRSYENAEL VSSKQLTAFS DHRFPLDSPD HISLPQYVNY
LKSYVDRFDL APYIKLGCRA IDITPLNSRD QKWKHRVRFI DGATGEEDQF DCSHVAICTG
LHVEPNIPLI PGIEDVQGDV FHSSRYKARS QLAGRDVLIL GCGETAMDIA YEAVKADAQS
VTMCYRTGFL SFPKALSRFQ VFGRQFKGGL PIDGLITNLF ETAYVHRAIA KSRLRWFVSD
FVIKRVLWLL SGTQAGMNQH VGGLPPERLG RAFVFLNKSN KAMPYLNRPY KKKNPILDFI
GNKYVDPPED ATSEKWVDTC TFPSCIDSTG KVIFEPRLDR KDWQRMKNKS VRPNCVIYCT
GYKQVFSWLD PYYPTAAETN IRNIIHSSHP DVAFIGFVRP GVGAIPPIAE QQAMWWTSLL
LGRMRVPTSP PHYHLLASKG SRIQYGVDYS AYMSTLARDF GGAPGLLQLY RRHSLRVLLV
YCFGASFVTF YRLVGPFESS DAPKIAMTEL AETILRRGIV GNLLFGVVPM VFYGILNAMA
YLLDLCGLIP EEKSVLLEPG AIEQIYLSG
//
