ID   R8CVL2_BACCE            Unreviewed;       698 AA.
AC   R8CVL2;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 29.
DE   RecName: Full=VWA domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=IGA_03905 {ECO:0000313|EMBL:EOO15684.1};
OS   Bacillus cereus HuA3-9.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus;
OC   Bacillus cereus group.
OX   NCBI_TaxID=1053205 {ECO:0000313|EMBL:EOO15684.1, ECO:0000313|Proteomes:UP000014003};
RN   [1] {ECO:0000313|EMBL:EOO15684.1, ECO:0000313|Proteomes:UP000014003}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HuA3-9 {ECO:0000313|EMBL:EOO15684.1,
RC   ECO:0000313|Proteomes:UP000014003};
RG   The Broad Institute Genome Sequencing Platform;
RG   The Broad Institute Genome Sequencing Center for Infectious Disease;
RA   Feldgarden M., Van der Auwera G.A., Mahillon J., Duprez V., Timmery S.,
RA   Mattelet C., Dierick K., Sun M., Yu Z., Zhu L., Hu X., Shank E.B.,
RA   Swiecicka I., Hansen B.M., Andrup L., Walker B., Young S.K., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA   Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA   Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA   Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Bacillus cereus HuA3-9.";
RL   Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EOO15684.1}.
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DR   EMBL; AHDZ01000032; EOO15684.1; -; Genomic_DNA.
DR   RefSeq; WP_016096374.1; NZ_KB976146.1.
DR   AlphaFoldDB; R8CVL2; -.
DR   PATRIC; fig|1053205.3.peg.3937; -.
DR   HOGENOM; CLU_372078_0_0_9; -.
DR   Proteomes; UP000014003; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd00198; vWFA; 1.
DR   Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR   InterPro; IPR036465; vWFA_dom_sf.
DR   SUPFAM; SSF53300; vWA-like; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius}; Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           24..698
FT                   /note="VWA domain-containing protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5004453769"
FT   TRANSMEM        561..581
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   698 AA;  80154 MW;  9AC3CBFB5788550A CRC64;
     MKIRICATFM LFLFICLPFS VFAKGEEAKE RVVSLVYDDS GSMRNNDRWK YANYALQSLV
     ALLDEKDKFS YVPMSKPNDP LNISLTKDQR QTEINGIGAW KTYLNTPFSA VETAMQSIKK
     EADIDGKREF WLIVLTDGAF NDLEKDKVGG KEQITQKLAQ FKKEMDSKKI SLHPVLITME
     EDLGQQEKEQ LNTFKEIWKK EMNGVVMPSS GEDGIVQSVN QVAALVANRD PFSSVESIVK
     TKIVGKKVEI TTPFPLKRMT LVRQSPSLSN YKVMQLSKPL QLQSSFSIHA PGEAKLFGNI
     VHVSTANQEV IKPGTYTIEV DQDIEKEGLQ VLVEPALNYT VSTYDKDDKD RKNVEKMYEG
     VTAVIEAKPT ELPIQTSYFE AEVEIDGKQY PMKWDDKRHV FYYETKVGKE LVRGKVHMNI
     KGFYRQTKEF KIEPAEKPKL TLQAVTKDYE EKVTNLENSK PFILQPQLNG KPMTEEAVKK
     LLKSTGVTSN QSINYELKQH GSQVYVYPRP YYSDTFNFTD TGTVEATITI NDSKLQEVKE
     KIVLHIENAP FFEKYALVFK FVIPITLLLL IVGIIILGWI VRPRFHRKAL LYYEWDQEVA
     KDWLYQSEPE LLKNKLWNHY FGIPFRAERK TVQSVTLIAK KGSKSIFVAK ESQVVGMIID
     GMFITEEEVG MEHKTLYPNE LLVIDRGYGK EIYRYECE
//