ID   R8VT01_9CLOT            Unreviewed;       458 AA.
AC   R8VT01;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 34.
DE   RecName: Full=M18 family aminopeptidase {ECO:0000256|RuleBase:RU004387};
DE            EC=3.4.11.- {ECO:0000256|RuleBase:RU004387};
GN   ORFNames=HMPREF1526_02832 {ECO:0000313|EMBL:EOQ35371.1};
OS   Butyricicoccus pullicaecorum 1.2.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Butyricicoccus.
OX   NCBI_TaxID=1203606 {ECO:0000313|EMBL:EOQ35371.1, ECO:0000313|Proteomes:UP000013981};
RN   [1] {ECO:0000313|EMBL:EOQ35371.1, ECO:0000313|Proteomes:UP000013981}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1.2 {ECO:0000313|EMBL:EOQ35371.1,
RC   ECO:0000313|Proteomes:UP000013981};
RG   The Broad Institute Genome Sequencing Platform;
RA   Earl A., Ward D., Feldgarden M., Gevers D., Van Immerseel F., Eeckhaut V.,
RA   Walker B., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA   Abouelleil A., Alvarado L., Arachchi H.M., Berlin A.M., Chapman S.B.,
RA   Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C.,
RA   Imamovic A., Larimer J., McCowan C., Murphy C., Neiman D., Pearson M.,
RA   Priest M., Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J.,
RA   Nusbaum C., Birren B.;
RT   "The Genome Sequence of Butyricicoccus pullicaecorum 1.2.";
RL   Submitted (JAN-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947,
CC         ECO:0000256|RuleBase:RU004387};
CC   -!- SIMILARITY: Belongs to the peptidase M18 family.
CC       {ECO:0000256|ARBA:ARBA00008290, ECO:0000256|RuleBase:RU004386}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EOQ35371.1}.
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DR   EMBL; AQOB01000015; EOQ35371.1; -; Genomic_DNA.
DR   RefSeq; WP_016148924.1; NZ_KB976105.1.
DR   AlphaFoldDB; R8VT01; -.
DR   PATRIC; fig|1203606.4.peg.2785; -.
DR   eggNOG; COG1362; Bacteria.
DR   HOGENOM; CLU_590123_0_0_9; -.
DR   OrthoDB; 89722at2; -.
DR   Proteomes; UP000013981; Unassembled WGS sequence.
DR   GO; GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   Gene3D; 2.30.250.10; Aminopeptidase i, Domain 2; 1.
DR   Gene3D; 3.40.630.10; Zn peptidases; 1.
DR   InterPro; IPR001948; Peptidase_M18.
DR   InterPro; IPR023358; Peptidase_M18_dom2.
DR   PANTHER; PTHR28570; ASPARTYL AMINOPEPTIDASE; 1.
DR   PANTHER; PTHR28570:SF2; M18 FAMILY AMINOPEPTIDASE 1-RELATED; 1.
DR   Pfam; PF02127; Peptidase_M18; 1.
DR   PRINTS; PR00932; AMINO1PTASE.
DR   SUPFAM; SSF101821; Aminopeptidase/glucanase lid domain; 1.
DR   SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
PE   3: Inferred from homology;
KW   Aminopeptidase {ECO:0000256|ARBA:ARBA00022438,
KW   ECO:0000256|RuleBase:RU004386};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU004386};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW   ECO:0000256|RuleBase:RU004386};
KW   Metalloprotease {ECO:0000256|ARBA:ARBA00023049,
KW   ECO:0000256|RuleBase:RU004386};
KW   Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|RuleBase:RU004386};
KW   Reference proteome {ECO:0000313|Proteomes:UP000013981};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU004386}.
SQ   SEQUENCE   458 AA;  50233 MW;  06D127A067C7A768 CRC64;
     MELFYDKKPG YDKLDKKACM DYAEGYKAFL DEGKTERDAV DAIVRMAEAK GYKAYVRGMA
     VNPGDKFYQI NRHKGIILAH IGSAPLSDGV RLTAAHLDAP RIDIRTVPLY EQDGMAYFKT
     HYYGGIKKYH WLAIPLELRG VVCVCRDGKV ERVPVHVGHK PGDPKFVITD LLPHLASEQM
     VKKATEVIKA ENMNVLLGSF PSENSADGDK DRVKRAILEY LNAEYGMTEA DFLSAELSCV
     PAFNACDIGF DRSLIGAYGH DDRVCSYPAA TALLDADETP VHTNLCLLVD KEEIGSDGVT
     GMQSRHFDTF LGDLCRAQNV LPDECYEHSI CLSADVCNAF DPNFPEVSEG RNDARIGCGM
     AIIKYTGARG KSGTSDASAE LMAQVRCILD GAGITWQTGQ LGRVDQGGGG TVAMYLANRN
     IDTVDAGVPV LSMHAPFETI SKHDLYMTYL GFGAFYRD
//