ID R9AIP2_WALI9 Unreviewed; 577 AA.
AC R9AIP2;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=DNA-directed RNA polymerase II subunit RPB3 {ECO:0000313|EMBL:EOR02082.1};
GN ORFNames=J056_003758 {ECO:0000313|EMBL:EOR02082.1};
OS Wallemia ichthyophaga (strain EXF-994 / CBS 113033).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Wallemiomycotina;
OC Wallemiomycetes; Wallemiales; Wallemiaceae; Wallemia.
OX NCBI_TaxID=1299270 {ECO:0000313|EMBL:EOR02082.1, ECO:0000313|Proteomes:UP000014064};
RN [1] {ECO:0000313|Proteomes:UP000014064}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EXF-994 / CBS 113033 {ECO:0000313|Proteomes:UP000014064};
RX PubMed=24034603; DOI=10.1186/1471-2164-14-617;
RA Zajc J., Liu Y., Dai W., Yang Z., Hu J., Gostincar C., Gunde-Cimerman N.;
RT "Genome and transcriptome sequencing of the halophilic fungus Wallemia
RT ichthyophaga: haloadaptations present and absent.";
RL BMC Genomics 14:617-617(2013).
CC -!- SIMILARITY: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase
CC subunit family. {ECO:0000256|ARBA:ARBA00025804}.
CC -!- SIMILARITY: Belongs to the methyltransferase superfamily. NTM1 family.
CC {ECO:0000256|ARBA:ARBA00009059}.
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DR EMBL; KE007228; EOR02082.1; -; Genomic_DNA.
DR RefSeq; XP_009267249.1; XM_009268974.1.
DR AlphaFoldDB; R9AIP2; -.
DR STRING; 1299270.R9AIP2; -.
DR GeneID; 20376710; -.
DR KEGG; wic:J056_003758; -.
DR eggNOG; KOG1522; Eukaryota.
DR eggNOG; KOG3178; Eukaryota.
DR HOGENOM; CLU_472674_0_0_1; -.
DR OrthoDB; 5472982at2759; -.
DR Proteomes; UP000014064; Unassembled WGS sequence.
DR GO; GO:0055029; C:nuclear DNA-directed RNA polymerase complex; IEA:UniProt.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:InterPro.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd07031; RNAP_II_RPB3; 1.
DR Gene3D; 2.170.120.12; DNA-directed RNA polymerase, insert domain; 1.
DR Gene3D; 3.30.1360.10; RNA polymerase, RBP11-like subunit; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR HAMAP; MF_00320; RNApol_arch_Rpo3; 1.
DR InterPro; IPR001514; DNA-dir_RNA_pol_30-40kDasu_CS.
DR InterPro; IPR011262; DNA-dir_RNA_pol_insert.
DR InterPro; IPR011263; DNA-dir_RNA_pol_RpoA/D/Rpb3.
DR InterPro; IPR008576; MeTrfase_NTM1.
DR InterPro; IPR036603; RBP11-like.
DR InterPro; IPR022842; RNAP_Rpo3/Rpb3/RPAC1.
DR InterPro; IPR036643; RNApol_insert_sf.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR11800; DNA-DIRECTED RNA POLYMERASE; 1.
DR PANTHER; PTHR11800:SF2; DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB3; 1.
DR Pfam; PF05891; Methyltransf_PK; 1.
DR Pfam; PF01000; RNA_pol_A_bac; 1.
DR Pfam; PF01193; RNA_pol_L; 1.
DR SMART; SM00662; RPOLD; 1.
DR SUPFAM; SSF56553; Insert subdomain of RNA polymerase alpha subunit; 1.
DR SUPFAM; SSF55257; RBP11-like subunits of RNA polymerase; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00446; RNA_POL_D_30KD; 1.
PE 3: Inferred from homology;
KW DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022478,
KW ECO:0000313|EMBL:EOR02082.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000014064};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 263..528
FT /note="DNA-directed RNA polymerase RpoA/D/Rpb3-type"
FT /evidence="ECO:0000259|SMART:SM00662"
FT REGION 463..493
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 577 AA; 64198 MW; D8C82C045D2BD6C7 CRC64;
MSRIPNFTKG VEYWNATEAT YNGVLGGFGL GTLPRVDAQS SRMMILKLLP RLSQTKSIMS
PNGGDAQHIK HTRALEAGAG VGRVSTDVLL YYSNHVELVE PTKKFTDVAR ERLSVHDKVK
EGSTWVVKEI GLQSWQPEGV YDLIWSQWCI PHLSDEELVT YLNKAKKALR RYESNDKYFG
QDGLVVVKEN ICSDSDYTLF DDEDSSITRS HQAYLDIFDK AGMSIVYQEV QLGFPKELYP
VRVYALSSTI TMRVRVRSLE AERINFVLEN ADLPLANALR RILIADLPTM AIDSVKIEEN
SSVLVDEFIS HRLGMVPLIS TACDKLINYN RDCVCMDSCP KCSVVLGLNI KCTTPETILV
TSNHLQVISQ EALDTSGNAI DPPIGLSSDF GLPINYHLED VHPITICKLR QGQELRITCL
AKKGINKEHA KWGPTSAVGF EYDPYNKFKH TSYWYEQDER SEWPLSSNAT EETPPEDSND
VNHPAQSNDS EPRNFYFDVE GTGALQPKDM LLSAFAELQN KLAAIVLALD HPADQQGDMN
SGNLVEGMDN TTGGAGASGV QALDDWAVNT AQGFDWS
//
