ID R9CD72_9CLOT Unreviewed; 686 AA.
AC R9CD72;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE RecName: Full=Flagellar biosynthesis protein FlhA {ECO:0000256|RuleBase:RU364093};
GN Name=flhA {ECO:0000256|RuleBase:RU364093,
GN ECO:0000313|EMBL:EOR27242.1};
GN ORFNames=A500_05696 {ECO:0000313|EMBL:EOR27242.1};
OS Clostridium sartagoforme AAU1.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1202534 {ECO:0000313|EMBL:EOR27242.1, ECO:0000313|Proteomes:UP000013988};
RN [1] {ECO:0000313|EMBL:EOR27242.1, ECO:0000313|Proteomes:UP000013988}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AAU1 {ECO:0000313|EMBL:EOR27242.1,
RC ECO:0000313|Proteomes:UP000013988};
RA Joshi C.G., Duggirala S.M., Nathani N.M., Bhatt V.D., Patel A.K.,
RA Pandya P.R., KaPatel J.A.;
RT "Whole genome shotgun sequencing of Clostridium sartagoforme AAU1.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for formation of the rod structure of the flagellar
CC apparatus. Together with FliI and FliH, may constitute the export
CC apparatus of flagellin. {ECO:0000256|RuleBase:RU364093}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU364093};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU364093}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the FHIPEP (flagella/HR/invasion proteins export
CC pore) family. {ECO:0000256|ARBA:ARBA00008835,
CC ECO:0000256|RuleBase:RU364093}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU364093}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EOR27242.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; ASRV01000065; EOR27242.1; -; Genomic_DNA.
DR AlphaFoldDB; R9CD72; -.
DR PATRIC; fig|1202534.3.peg.1144; -.
DR OrthoDB; 9759185at2; -.
DR Proteomes; UP000013988; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0044780; P:bacterial-type flagellum assembly; IEA:InterPro.
DR GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR Gene3D; 3.40.30.60; FHIPEP family, domain 1; 1.
DR Gene3D; 1.10.8.540; FHIPEP family, domain 3; 1.
DR Gene3D; 3.40.50.12790; FHIPEP family, domain 4; 1.
DR InterPro; IPR042194; FHIPEP_1.
DR InterPro; IPR042193; FHIPEP_3.
DR InterPro; IPR042196; FHIPEP_4.
DR InterPro; IPR025505; FHIPEP_CS.
DR InterPro; IPR006301; FlhA.
DR InterPro; IPR001712; T3SS_FHIPEP.
DR NCBIfam; TIGR01398; FlhA; 1.
DR PANTHER; PTHR30161:SF1; FLAGELLAR BIOSYNTHESIS PROTEIN FLHA-RELATED; 1.
DR PANTHER; PTHR30161; FLAGELLAR EXPORT PROTEIN, MEMBRANE FLHA SUBUNIT-RELATED; 1.
DR Pfam; PF00771; FHIPEP; 1.
DR PIRSF; PIRSF005419; FlhA; 1.
DR PRINTS; PR00949; TYPE3IMAPROT.
DR PROSITE; PS00994; FHIPEP; 1.
PE 3: Inferred from homology;
KW Bacterial flagellum biogenesis {ECO:0000256|RuleBase:RU364093};
KW Bacterial flagellum protein export {ECO:0000256|RuleBase:RU364093};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|RuleBase:RU364093};
KW Cell projection {ECO:0000313|EMBL:EOR27242.1};
KW Cilium {ECO:0000313|EMBL:EOR27242.1}; Coiled coil {ECO:0000256|SAM:Coils};
KW Flagellum {ECO:0000313|EMBL:EOR27242.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU364093};
KW Protein transport {ECO:0000256|RuleBase:RU364093};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU364093};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU364093}; Transport {ECO:0000256|RuleBase:RU364093}.
FT TRANSMEM 12..33
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 39..58
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 70..90
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 110..133
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 197..218
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 272..292
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT COILED 312..339
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 686 AA; 75326 MW; 7C98D6A8CA734FE0 CRC64;
MLANEKFSLN RNMDVLVAFG VLGIVLMIII PLPPLLLDIL LAFNITLSAV VIMITMFTTN
VLQLSVFPTL LLITTLFRLG LNISSTRLIL SEGNAGSIIE AFGEFVIGGN YIVGIIIFLI
IIIIQFVVIT NGAGRVSEVS ARFTLDAMPG KQMSIDADLN AGTIDEATAR KRREDLQAEA
DFYGSMDGAS KFVKGDAIAG IIITIINIVA GIIIGTMGGM DIAKAAQLYT RLTVGDGLVS
QIPALLISTA SGILVTRSGS SDNFGKTFSK QLTAFPVALA IVSAVMFFLA LIPAMPKLPF
LLAAVTSGVA AYLLFKEEQK NQEEELAKVE EEYTEMERKE PENVMTLISV EPMEVEIGYG
LIPLADESTG GDLLQRIASV RRQCAIEMGV VVQPIRIRDN LQLKTNEYVI KIRGTVIASA
ELMANMLLCM DPSGDNSQIA GIRTIEPTFN LPAVWINKDQ REEAEIKGLT VVDPTTVMVT
HLTETIKAHS YELLGRQEVQ LIVDNTKEKY STVVEELIPD LMTIGELQKI LQNLLREKVP
IKDMVTIMES LADNSRLTKD LELLTEYVRF ALARTICNTV IDENRSITVV TLSPQIEEII
AANTQKSMQG SFPAVDPDTT TKILSSIRDE VDRVYFYNNQ PVILVSPNIR PVFRKLIEMV
FPHIMVISLN EIPNDVEIRT EGVVSL
//
