ID R9ILW1_9FIRM Unreviewed; 490 AA.
AC R9ILW1;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE RecName: Full=RND efflux pump membrane fusion protein barrel-sandwich domain-containing protein {ECO:0000259|Pfam:PF16576};
GN ORFNames=C806_03540 {ECO:0000313|EMBL:EOS22919.1};
OS Lachnospiraceae bacterium 3-1.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX NCBI_TaxID=397288 {ECO:0000313|EMBL:EOS22919.1, ECO:0000313|Proteomes:UP000014188};
RN [1] {ECO:0000313|EMBL:EOS22919.1, ECO:0000313|Proteomes:UP000014188}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=3-1 {ECO:0000313|EMBL:EOS22919.1,
RC ECO:0000313|Proteomes:UP000014188};
RG The Broad Institute Genomics Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Earl A., Xavier R., Elson C., Duck W., Walker B., Young S., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Lachnospiraceae bacterium 3-1.";
RL Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EOS22919.1}.
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DR EMBL; ASST01000020; EOS22919.1; -; Genomic_DNA.
DR AlphaFoldDB; R9ILW1; -.
DR STRING; 397288.C806_03540; -.
DR PATRIC; fig|397288.3.peg.3835; -.
DR eggNOG; COG0845; Bacteria.
DR HOGENOM; CLU_032046_0_0_9; -.
DR Proteomes; UP000014188; Unassembled WGS sequence.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR InterPro; IPR032317; HlyD_D23.
DR PANTHER; PTHR30469:SF15; HLYD FAMILY OF SECRETION PROTEINS; 1.
DR PANTHER; PTHR30469; MULTIDRUG RESISTANCE PROTEIN MDTA; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000014188}.
FT DOMAIN 61..261
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
FT REGION 392..490
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 102..179
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 403..428
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 443..457
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 458..490
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 490 AA; 54187 MW; 1ED6D691C4CE03A9 CRC64;
MNKKKMGIIA AAVVVVVAAT GGGAWYFLKG NGGSGNSADK VYVETVESLT SANSGSQSRY
SGVVEAQETW DVNKDAEREI KEVFVKKGDM VEEGTPLFEY DMEEVEGEIQ QAQLELEGMQ
NEISSLQSQI NQLTKERNSA PAEDKFEYTA DIQEKQNSIK QSEYNIESKK AEIQKKQESM
EKAVVTSKIA GVVKAINETE SDMMGESTAY MTVLAVGDYR VKGTVTETNV QFLSEGQPVI
LRSRIDEEQT WAGTINKIDT QNEEKNDNNG YYESDGGAEK ATKYPFYVTL ESSEGLMMGQ
HIFIEMDEGQ TEQKEGIWLF EAYIVQEEET AFVWVANDKN RLEKREVELG EYDENLGAYE
ITSGLAKEDA IAFPMEGLYE GVATVTDMSE VDYSSPLYNP EGEEGDEMSE EGDDMSGEGD
ETFPEDGENS DGDAGMTPES DFDLGGEGRR LDDSNGDSEE GELYSESPEE GSEESDIQEN
VDDEEPQDGE
//
