ID R9IYS3_9FIRM Unreviewed; 639 AA.
AC R9IYS3;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE RecName: Full=Flagellar hook-associated protein 2 {ECO:0000256|RuleBase:RU362066};
DE Short=HAP2 {ECO:0000256|RuleBase:RU362066};
DE AltName: Full=Flagellar cap protein {ECO:0000256|RuleBase:RU362066};
GN ORFNames=C806_00657 {ECO:0000313|EMBL:EOS27064.1};
OS Lachnospiraceae bacterium 3-1.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX NCBI_TaxID=397288 {ECO:0000313|EMBL:EOS27064.1, ECO:0000313|Proteomes:UP000014188};
RN [1] {ECO:0000313|EMBL:EOS27064.1, ECO:0000313|Proteomes:UP000014188}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=3-1 {ECO:0000313|EMBL:EOS27064.1,
RC ECO:0000313|Proteomes:UP000014188};
RG The Broad Institute Genomics Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Earl A., Xavier R., Elson C., Duck W., Walker B., Young S., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Lachnospiraceae bacterium 3-1.";
RL Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for morphogenesis and for the elongation of the
CC flagellar filament by facilitating polymerization of the flagellin
CC monomers at the tip of growing filament. Forms a capping structure,
CC which prevents flagellin subunits (transported through the central
CC channel of the flagellum) from leaking out without polymerization at
CC the distal end. {ECO:0000256|RuleBase:RU362066}.
CC -!- SUBUNIT: Homopentamer. {ECO:0000256|ARBA:ARBA00011255,
CC ECO:0000256|RuleBase:RU362066}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|RuleBase:RU362066}.
CC Bacterial flagellum {ECO:0000256|RuleBase:RU362066}.
CC -!- SIMILARITY: Belongs to the FliD family. {ECO:0000256|ARBA:ARBA00009764,
CC ECO:0000256|RuleBase:RU362066}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EOS27064.1}.
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DR EMBL; ASST01000003; EOS27064.1; -; Genomic_DNA.
DR AlphaFoldDB; R9IYS3; -.
DR STRING; 397288.C806_00657; -.
DR PATRIC; fig|397288.3.peg.715; -.
DR eggNOG; COG1345; Bacteria.
DR HOGENOM; CLU_015182_0_0_9; -.
DR OrthoDB; 9776025at2; -.
DR Proteomes; UP000014188; Unassembled WGS sequence.
DR GO; GO:0009421; C:bacterial-type flagellum filament cap; IEA:InterPro.
DR GO; GO:0009424; C:bacterial-type flagellum hook; IEA:UniProtKB-UniRule.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR InterPro; IPR040026; FliD.
DR InterPro; IPR010809; FliD_C.
DR InterPro; IPR003481; FliD_N.
DR PANTHER; PTHR30288; FLAGELLAR CAP/ASSEMBLY PROTEIN FLID; 1.
DR PANTHER; PTHR30288:SF0; FLAGELLAR HOOK-ASSOCIATED PROTEIN 2; 1.
DR Pfam; PF07195; FliD_C; 1.
DR Pfam; PF02465; FliD_N; 1.
PE 3: Inferred from homology;
KW Bacterial flagellum {ECO:0000256|ARBA:ARBA00023143,
KW ECO:0000256|RuleBase:RU362066};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|RuleBase:RU362066};
KW Reference proteome {ECO:0000313|Proteomes:UP000014188};
KW Secreted {ECO:0000256|RuleBase:RU362066}.
FT DOMAIN 10..107
FT /note="Flagellar hook-associated protein 2 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02465"
FT DOMAIN 367..628
FT /note="Flagellar hook-associated protein 2 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07195"
FT COILED 584..611
FT /evidence="ECO:0000256|RuleBase:RU362066"
SQ SEQUENCE 639 AA; 69540 MW; 543339447AE41D8E CRC64;
MAIRISGLNS GLDTDSIVQE LVSAYRTKQD KYKKAQTKLS WKQDAWKDMN TKIYNFYSKT
LSNMRRIGNF TNKKKTTISD STKATVSASS SVVNGTQTLK VNQLAKAGYL TGTKLELKDG
QKIEKKTALS ELGITSGTLK FQVGGETKSV EVNESMTVSD FTKALSEQGV TANFDVAQQR
FFLQSANTGL SNDFNFVVDD GDKNAFNILN NLGLATAENY DAVAGDYATA SNGSIIGAGK
FVSMSGQISD NTLLSGLGIQ SGTMKFKVNG VEKTVAVDAD NMTVSQLKDA FKQEGMDLQY
NSAAGAFVLG GLNPGESVEL VASKDADGKE SFNVANSLGL ATKKAYEVAG ADAVDTSDMD
FAVKVKAENA QIELNGAVFE GESNTFSING LNITATGVSD EMTITTATDV DGIYDMVKGF
LKEYSELMNA MEAAYNAPTS KGYEPLTDDE KDSMSDKEVE KWETKIKDSI LRRDDTLRTV
MSGMSSNMAK VFEVNGKSYS LASFGIKTAG YFNAAENESY AYHIDGDADD SVSSSNEDKL
RKMIEEDPDA VGQFFTQLAT SVYDNLHEKM GTTALSSIYK VYNDKQMKSE YDEYTKTIKK
WEDKLKDMED YYYNKFSAME TALAKLQSQT NSLSSLLGG
//
