ID   R9J337_9FIRM            Unreviewed;       126 AA.
AC   R9J337;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   RecName: Full=Holin-like protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=C804_03765 {ECO:0000313|EMBL:EOS28426.1};
OS   Lachnospiraceae bacterium A4.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX   NCBI_TaxID=397291 {ECO:0000313|EMBL:EOS28426.1, ECO:0000313|Proteomes:UP000014118};
RN   [1] {ECO:0000313|EMBL:EOS28426.1, ECO:0000313|Proteomes:UP000014118}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=A4 {ECO:0000313|EMBL:EOS28426.1,
RC   ECO:0000313|Proteomes:UP000014118};
RG   The Broad Institute Genomics Platform;
RG   The Broad Institute Genome Sequencing Center for Infectious Disease;
RA   Earl A., Xavier R., Elson C., Duck W., Walker B., Young S., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Lachnospiraceae bacterium A4.";
RL   Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EOS28426.1}.
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DR   EMBL; ASSR01000074; EOS28426.1; -; Genomic_DNA.
DR   AlphaFoldDB; R9J337; -.
DR   STRING; 397291.C804_03765; -.
DR   PATRIC; fig|397291.3.peg.3878; -.
DR   eggNOG; COG1380; Bacteria.
DR   HOGENOM; CLU_113736_2_0_9; -.
DR   OrthoDB; 3176438at2; -.
DR   Proteomes; UP000014118; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR005538; LrgA/CidA.
DR   PANTHER; PTHR33931:SF2; HOLIN-LIKE PROTEIN CIDA; 1.
DR   PANTHER; PTHR33931; HOLIN-LIKE PROTEIN CIDA-RELATED; 1.
DR   Pfam; PF03788; LrgA; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000014118};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        7..24
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        30..49
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        58..78
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        84..111
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   126 AA;  14059 MW;  00AFDC084A165FAE CRC64;
     MKYLKQFTII LFVSFLGELL HLVIPLPIPA SVYGLVLMLL ALCFGILHLE QVKAAADFLI
     EIMPVMFIPA AVGLLDSWSA LQPIFIPVVL ITILTTIIVM GVTGQVTQCM IRRAQRKKSR
     KEQPNK
//