ID   R9JB62_9FIRM            Unreviewed;       222 AA.
AC   R9JB62;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   27-MAR-2024, entry version 33.
DE   RecName: Full=RNase H type-1 domain-containing protein {ECO:0000259|PROSITE:PS50879};
GN   ORFNames=C807_01814 {ECO:0000313|EMBL:EOS31236.1};
OS   Lachnospiraceae bacterium 28-4.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX   NCBI_TaxID=397287 {ECO:0000313|EMBL:EOS31236.1, ECO:0000313|Proteomes:UP000014112};
RN   [1] {ECO:0000313|EMBL:EOS31236.1, ECO:0000313|Proteomes:UP000014112}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=28-4 {ECO:0000313|EMBL:EOS31236.1,
RC   ECO:0000313|Proteomes:UP000014112};
RG   The Broad Institute Genomics Platform;
RG   The Broad Institute Genome Sequencing Center for Infectious Disease;
RA   Earl A., Xavier R., Elson C., Duck W., Walker B., Young S., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Lachnospiraceae bacterium 28-4.";
RL   Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EOS31236.1}.
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DR   EMBL; ASSU01000015; EOS31236.1; -; Genomic_DNA.
DR   AlphaFoldDB; R9JB62; -.
DR   STRING; 397287.C807_01814; -.
DR   PATRIC; fig|397287.3.peg.1953; -.
DR   eggNOG; COG3341; Bacteria.
DR   HOGENOM; CLU_030894_2_1_9; -.
DR   OrthoDB; 9811552at2; -.
DR   Proteomes; UP000014112; Unassembled WGS sequence.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IEA:InterPro.
DR   GO; GO:0090304; P:nucleic acid metabolic process; IEA:UniProt.
DR   CDD; cd09277; RNase_HI_bacteria_like; 1.
DR   Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR   Gene3D; 3.40.970.10; Ribonuclease H1, N-terminal domain; 1.
DR   InterPro; IPR009027; Ribosomal_bL9/RNase_H1_N.
DR   InterPro; IPR011320; RNase_H1_N.
DR   InterPro; IPR037056; RNase_H1_N_sf.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR002156; RNaseH_domain.
DR   InterPro; IPR036397; RNaseH_sf.
DR   Pfam; PF01693; Cauli_VI; 1.
DR   Pfam; PF00075; RNase_H; 1.
DR   SUPFAM; SSF55658; L9 N-domain-like; 1.
DR   SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR   PROSITE; PS50879; RNASE_H_1; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000014112}.
FT   DOMAIN          68..206
FT                   /note="RNase H type-1"
FT                   /evidence="ECO:0000259|PROSITE:PS50879"
SQ   SEQUENCE   222 AA;  24844 MW;  C303796DE1E07584 CRC64;
     MAKKKYYAVR KGLRTGIFES WQECQAVVSG YGSAEYKSFS TREEARNYLG GTDGGKEEAA
     AEENFEQGPE KVIAYVDGSY DDKLKKYSFG CILLLPSGDI VKESGNGNNP ESLAIRNVAG
     EMLGAMYAVK WAMINGYSEV ELRYDYEGIE KWVQGIWKAK NELAQKYAAA MNDWKRSIRI
     SFLKIAAHSN NRYNDMADEL AKSAIIHGNG IPKISRYNAE PE
//