ID R9KH44_9FIRM Unreviewed; 744 AA.
AC R9KH44;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE RecName: Full=ATP-dependent DNA helicase RecG {ECO:0000256|ARBA:ARBA00017846};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN ORFNames=C810_02493 {ECO:0000313|EMBL:EOS45623.1};
OS Lachnospiraceae bacterium A2.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX NCBI_TaxID=397290 {ECO:0000313|EMBL:EOS45623.1, ECO:0000313|Proteomes:UP000014150};
RN [1] {ECO:0000313|EMBL:EOS45623.1, ECO:0000313|Proteomes:UP000014150}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A2 {ECO:0000313|EMBL:EOS45623.1,
RC ECO:0000313|Proteomes:UP000014150};
RG The Broad Institute Genomics Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Earl A., Xavier R., Elson C., Duck W., Walker B., Young S., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Lachnospiraceae bacterium A2.";
RL Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the helicase family. RecG subfamily.
CC {ECO:0000256|ARBA:ARBA00007504}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EOS45623.1}.
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DR EMBL; ASSX01000012; EOS45623.1; -; Genomic_DNA.
DR AlphaFoldDB; R9KH44; -.
DR STRING; 397290.C810_02493; -.
DR PATRIC; fig|397290.3.peg.2757; -.
DR eggNOG; COG1200; Bacteria.
DR HOGENOM; CLU_005122_7_1_9; -.
DR OrthoDB; 9804325at2; -.
DR Proteomes; UP000014150; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR CDD; cd04488; RecG_wedge_OBF; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR047112; RecG/Mfd.
DR InterPro; IPR045562; RecG_dom3_C.
DR InterPro; IPR033454; RecG_wedge.
DR PANTHER; PTHR47964; ATP-DEPENDENT DNA HELICASE HOMOLOG RECG, CHLOROPLASTIC; 1.
DR PANTHER; PTHR47964:SF1; ATP-DEPENDENT DNA HELICASE HOMOLOG RECG, CHLOROPLASTIC; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF19833; RecG_dom3_C; 1.
DR Pfam; PF17191; RecG_wedge; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:EOS45623.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000014150}.
FT DOMAIN 330..493
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 512..672
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
SQ SEQUENCE 744 AA; 83272 MW; 68D00C7357B61971 CRC64;
MDKTSSIGAL KGIGAKTEQL FHNLGVYTIG DILLHYPRDY DRLPPITPLA GLAGLMEGKP
IPGHGTDLEQ KEEGHCQRMG EATAAVAAQI KKTPSVRAGR NMQVTSLILQ EQGVTLDLVW
FRMPYLRSTL KPGEWFLFLG KVTRKGNQFH MEQPQIFQPE KYAAMQESLW PCYALTAGLG
KNKVSKAIKQ ALEALDLSVD YLPEEIRARR GLAEYHFAIE NIHFPESEEA LAQARNRLIF
DEFFQFILSA GIQKGQMEEV LNGFSFLPLV EGPICQVSEE PQEDPQGQLA EGLPGQEQPM
QPLWADMVIQ HLPYRLTGAQ QRTLQEIRRD LRGRKVMQRL VQGDVGSGKT ILAFLAMLDV
SQSGYQSALM APTEVLAVQH FQTFTELCGD NGLQIPIILL TGTLTQKEKR RAYERMQLYP
NAMVIGTHAL IQERALYDSL ALVITDEQHR FGVKQRESLF LKGSQPHILV MSATPIPRTL
AIILYGDLDI SVVDEVPAKR LPIKSCVVGK SSRKASYDFL KKEIALGHQA YVICPLVEES
EGLEAENVTD YAEALRGQFP PGIVVETLHG KMKSGRKNLV MEQFARNEIQ VLVSTTVVEV
GVNVPNATVM MVEDAQRFGL AQLHQLRGRV GRGDAQSYCI MVNTTDSSKA KKRLEILNRS
NDGFFIAGED LKLRGPGDFF GIRQSGLLEF RLGDIYQNSD LLKQASEEAN RLLLEDRMLE
LPEHRNIKEQ IQLFLDRQGE TVNL
//
