ID R9LKE0_9BACL Unreviewed; 782 AA.
AC R9LKE0;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE RecName: Full=Beta-galactosidase {ECO:0000256|RuleBase:RU000675};
DE EC=3.2.1.23 {ECO:0000256|RuleBase:RU000675};
GN ORFNames=C812_00151 {ECO:0000313|EMBL:EOS58806.1};
OS Paenibacillus barengoltzii G22.
OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Paenibacillus.
OX NCBI_TaxID=1235795 {ECO:0000313|EMBL:EOS58806.1, ECO:0000313|Proteomes:UP000019598};
RN [1] {ECO:0000313|EMBL:EOS58806.1, ECO:0000313|Proteomes:UP000019598}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=G22 {ECO:0000313|EMBL:EOS58806.1,
RC ECO:0000313|Proteomes:UP000019598};
RG The Broad Institute Genomics Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Earl A., Xavier R., Elson C., Duck W., Walker B., Young S., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Paenibacillus barengoltzii G22.";
RL Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal non-reducing beta-D-galactose residues
CC in beta-D-galactosides.; EC=3.2.1.23;
CC Evidence={ECO:0000256|RuleBase:RU000675};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 35 family.
CC {ECO:0000256|ARBA:ARBA00009809, ECO:0000256|RuleBase:RU003679}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EOS58806.1}.
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DR EMBL; ASSZ01000003; EOS58806.1; -; Genomic_DNA.
DR RefSeq; WP_016310789.1; NZ_KE159652.1.
DR AlphaFoldDB; R9LKE0; -.
DR STRING; 1235795.C812_00151; -.
DR PATRIC; fig|1235795.3.peg.140; -.
DR HOGENOM; CLU_018711_0_0_9; -.
DR OrthoDB; 9813184at2; -.
DR Proteomes; UP000019598; Unassembled WGS sequence.
DR GO; GO:0004565; F:beta-galactosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 2.102.20.10; Beta-galactosidase, domain 2; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR018954; Betagal_dom2.
DR InterPro; IPR037110; Betagal_dom2_sf.
DR InterPro; IPR031330; Gly_Hdrlase_35_cat.
DR InterPro; IPR019801; Glyco_hydro_35_CS.
DR InterPro; IPR001944; Glycoside_Hdrlase_35.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR23421:SF165; BETA-GALACTOSIDASE; 1.
DR PANTHER; PTHR23421; BETA-GALACTOSIDASE RELATED; 1.
DR Pfam; PF10435; BetaGal_dom2; 1.
DR Pfam; PF01301; Glyco_hydro_35; 1.
DR PRINTS; PR00742; GLHYDRLASE35.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF51011; Glycosyl hydrolase domain; 1.
DR PROSITE; PS01182; GLYCOSYL_HYDROL_F35; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU000675};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU000675}.
FT DOMAIN 45..385
FT /note="Glycoside hydrolase 35 catalytic"
FT /evidence="ECO:0000259|Pfam:PF01301"
FT DOMAIN 424..577
FT /note="Beta-galactosidase"
FT /evidence="ECO:0000259|Pfam:PF10435"
SQ SEQUENCE 782 AA; 87386 MW; 4E3DD50972D334E3 CRC64;
MTNHTAAILR LEIGQANKTI RPGKLALHAG SNPKGESFGF TNFYMTRNGE PVIPVVGEFH
FSRFSYLHWE EELLKMKAGG VHVVATYVFW NFHEEEEGVF DWSGNRNLRH FIDLCAKHEL
PLILRIGPFC HGEVRNGGIP DWVFRYPLEV RSNDERYLSL ARRLYREIAR QIQGTYYQEG
GPVIAVQLEN EYMHAGAPLD AWGYSSGQYV TAGTEGSAHL DELRRIAEEV GIRPLFFTAT
AWGGAAVPED GTLPMLAGYA YTPWIPNQPP SREFLFQDLH VTPAEPVKYD SLEYPVAYCE
MAGGMQVSYK ARPYVPAESV EAMTLVKLGS GSNLLGYYMY HGGSNPTGRK TFLNESGLPK
ITYDYQSPLG EFGRVGDSYD RIRAMSLFLQ SFGHLLAPMG TVLPVGQEQI APEDTQSIRW
CVRQKDGSGF VFLNNFQDHI NLPDRQLRIE LDTPKGKVCF PQTGELALRS GLGAILPFNL
ELDGLLIVSA TAQLLTRLET GDETVLVFYA HDGMEPEIVL RKSSVSEVGG EECHGVVEED
EANWILRPAA GHQHQIRVKT AEGRVVRLVT LTRTEALQTY RFDGLWGRDT LVISTSHLVM
KDGQLICTLP GQTQVTLSLF PAPVPLAELR SSAGMLQAAA KPDGGVFQTY ALDFTAYSPE
LTLNSPSDRS VLVDVPADWP ESVSDLWLRI EYDGDVAAAY LGDRMLTDHI HYGQPWEIGL
KQVRHELENH PLHLSITPLR RGTVHSYVNQ AYVERFEGVE IAKLHDIQAI PHYAARLWTQ
GK
//
