ID R9LMH9_9FIRM Unreviewed; 441 AA.
AC R9LMH9;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE RecName: Full=PmbA protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=C815_01823 {ECO:0000313|EMBL:EOS59970.1};
OS Firmicutes bacterium M10-2.
OC Bacteria; Bacillota.
OX NCBI_TaxID=1235796 {ECO:0000313|EMBL:EOS59970.1, ECO:0000313|Proteomes:UP000014154};
RN [1] {ECO:0000313|EMBL:EOS59970.1, ECO:0000313|Proteomes:UP000014154}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M10-2 {ECO:0000313|EMBL:EOS59970.1,
RC ECO:0000313|Proteomes:UP000014154};
RG The Broad Institute Genomics Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Earl A., Xavier R., Elson C., Duck W., Walker B., Young S., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Firmicutes bacterium M10-2.";
RL Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase U62 family.
CC {ECO:0000256|ARBA:ARBA00005836}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EOS59970.1}.
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DR EMBL; ASTB01000037; EOS59970.1; -; Genomic_DNA.
DR AlphaFoldDB; R9LMH9; -.
DR STRING; 1235796.C815_01823; -.
DR PATRIC; fig|1235796.3.peg.1837; -.
DR eggNOG; COG0312; Bacteria.
DR HOGENOM; CLU_026425_4_0_9; -.
DR OrthoDB; 9803618at2; -.
DR Proteomes; UP000014154; Unassembled WGS sequence.
DR GO; GO:0008237; F:metallopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR Gene3D; 3.30.2290.10; PmbA/TldD superfamily; 1.
DR InterPro; IPR045569; Metalloprtase-TldD/E_C.
DR InterPro; IPR045570; Metalloprtase-TldD/E_cen_dom.
DR InterPro; IPR002510; Metalloprtase-TldD/E_N.
DR InterPro; IPR047657; PmbA.
DR InterPro; IPR035068; TldD/PmbA_N.
DR InterPro; IPR036059; TldD/PmbA_sf.
DR PANTHER; PTHR43421; METALLOPROTEASE PMBA; 1.
DR PANTHER; PTHR43421:SF1; METALLOPROTEASE PMBA; 1.
DR Pfam; PF01523; PmbA_TldD_1st; 1.
DR Pfam; PF19290; PmbA_TldD_2nd; 1.
DR Pfam; PF19289; PmbA_TldD_3rd; 1.
DR SUPFAM; SSF111283; Putative modulator of DNA gyrase, PmbA/TldD; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000014154}.
FT DOMAIN 19..78
FT /note="Metalloprotease TldD/E N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01523"
FT DOMAIN 110..209
FT /note="Metalloprotease TldD/E central"
FT /evidence="ECO:0000259|Pfam:PF19290"
FT DOMAIN 221..440
FT /note="Metalloprotease TldD/E C-terminal"
FT /evidence="ECO:0000259|Pfam:PF19289"
SQ SEQUENCE 441 AA; 48908 MW; A5F947BC54E81C04 CRC64;
MNKQAWIERA KELGLEQFEI YQALSSEKEF TWFQGEIDTF VTSKVLGTSL RAIKNGNVAT
LTLENVEDET MDEALNALAQ QTEVITSTET VSLTEAQEVE IIENPHHFKM LTVEQIEQML
KNIESKALAY DSKIVQVAYL GYEQASGRRE ITNSLGVELS DEDQVQYVAC SVVAQDKDSF
KDATKIKVIF DHDSFDEDQF VKEVCEEALG KCGAHSIPSR MCPVIFEKDA MTSLLGAFTG
LFSGDMIAKG ISPLAKDLGK KVFSEQITIF DDPKNTDALS IASFDDEGYP TRRKVVVDHG
VFEQPLFDAR SAIKMNTKST GNGFKSGYAS SVHVSPMNMW IEPGNKDLDQ LMETMQEGVV
ITDIMGLHAG LHFASTQFSL QASGYLVKEG KKSDPVTLIT VAGRFLDLMN DVWEVGSDLE
WTYKQIVSPS ILFKNCAISG E
//
