ID   R9MGA5_9FIRM            Unreviewed;       483 AA.
AC   R9MGA5;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   27-MAR-2024, entry version 32.
DE   RecName: Full=Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=C818_02032 {ECO:0000313|EMBL:EOS70060.1};
OS   Lachnospiraceae bacterium MD308.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX   NCBI_TaxID=1235799 {ECO:0000313|EMBL:EOS70060.1, ECO:0000313|Proteomes:UP000014117};
RN   [1] {ECO:0000313|EMBL:EOS70060.1, ECO:0000313|Proteomes:UP000014117}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=3-2 {ECO:0000313|EMBL:EOS70060.1,
RC   ECO:0000313|Proteomes:UP000014117};
RG   The Broad Institute Genomics Platform;
RG   The Broad Institute Genome Sequencing Center for Infectious Disease;
RA   Earl A., Xavier R., Elson C., Duck W., Walker B., Young S., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Lachnospiraceae bacterium 3-2.";
RL   Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933};
CC   -!- SIMILARITY: Belongs to the Orn/Lys/Arg decarboxylase class-I family.
CC       {ECO:0000256|ARBA:ARBA00010671}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EOS70060.1}.
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DR   EMBL; ASTE01000021; EOS70060.1; -; Genomic_DNA.
DR   AlphaFoldDB; R9MGA5; -.
DR   STRING; 1235799.C818_02032; -.
DR   PATRIC; fig|1235799.3.peg.2145; -.
DR   eggNOG; COG1982; Bacteria.
DR   HOGENOM; CLU_025925_1_1_9; -.
DR   OrthoDB; 9815233at2; -.
DR   Proteomes; UP000014117; Unassembled WGS sequence.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   Gene3D; 3.90.105.10; Molybdopterin biosynthesis moea protein, domain 2; 1.
DR   Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR   InterPro; IPR000310; Orn/Lys/Arg_deCO2ase_major_dom.
DR   InterPro; IPR008286; Prn/Lys/Arg_de-COase_C.
DR   InterPro; IPR036633; Prn/Lys/Arg_de-COase_C_sf.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   PANTHER; PTHR43277; ARGININE DECARBOXYLASE; 1.
DR   PANTHER; PTHR43277:SF3; LYSINE DECARBOXYLASE; 1.
DR   Pfam; PF01276; OKR_DC_1; 1.
DR   Pfam; PF03711; OKR_DC_1_C; 1.
DR   SUPFAM; SSF55904; Ornithine decarboxylase C-terminal domain; 1.
DR   SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE   3: Inferred from homology;
KW   Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW   Reference proteome {ECO:0000313|Proteomes:UP000014117}.
FT   DOMAIN          4..302
FT                   /note="Orn/Lys/Arg decarboxylases family 1 pyridoxal-P
FT                   attachment site"
FT                   /evidence="ECO:0000259|Pfam:PF01276"
FT   DOMAIN          357..450
FT                   /note="Orn/Lys/Arg decarboxylase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF03711"
SQ   SEQUENCE   483 AA;  54482 MW;  54B468A25723AAED CRC64;
     MSTLYDKLRS YSNSDYYGFH MPGHKRRGIP AYDFGDGALP YEIDITEIEG FDDLHHPRGI
     LKSAQERAAE VYHADETHFL VNGSTVGILS AVCGVTEKGD TILVARNCHK SVYHAIYLNE
     LNPVYLYPDF DGKVNLNMQI RPQDVRDALE RYPDIRAVVI VSPTYDGVVS DVTAIAEAVH
     EKGLPLIVDE AHGAHFGFHS VFPENSNVRG ADIVIHSVHK TLPSLTQTAL LHMNGSRIDR
     DRVKGYLDML QTSSPSYVLM AAIDLCMEEL SNHAEEMFGD YVKELCEVRK KLSGLKCLEL
     IRTECYDISK LIIFTGNREF TGQELYRRLL SEYHLQMEMA AGSYVLAMTS VSDTKEGLER
     LTNALFRIDN KTSFQKTEEC PGVRTIPRAE VVCNIADVQR KVRMGAAEPM LVPWEAAAGY
     VSAEYAYLYP PGSPLIVPGE RITEEAVRML CWYRDKGFSV EGLKRERYVE VLKIKREIQH
     GKL
//