ID   R9MP97_9FIRM            Unreviewed;       403 AA.
AC   R9MP97;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   RecName: Full=HTH marR-type domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=C817_05431 {ECO:0000313|EMBL:EOS72496.1};
OS   Dorea sp. 5-2.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Dorea.
OX   NCBI_TaxID=1235798 {ECO:0000313|EMBL:EOS72496.1, ECO:0000313|Proteomes:UP000014211};
RN   [1] {ECO:0000313|EMBL:EOS72496.1, ECO:0000313|Proteomes:UP000014211}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=5-2 {ECO:0000313|EMBL:EOS72496.1,
RC   ECO:0000313|Proteomes:UP000014211};
RG   The Broad Institute Genomics Platform;
RG   The Broad Institute Genome Sequencing Center for Infectious Disease;
RA   Earl A., Xavier R., Elson C., Duck W., Walker B., Young S., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Dorea bacterium 5-2.";
RL   Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Transcriptional repressor of xylose-utilizing enzymes.
CC       {ECO:0000256|ARBA:ARBA00002486}.
CC   -!- SIMILARITY: Belongs to the ROK (NagC/XylR) family.
CC       {ECO:0000256|ARBA:ARBA00006479}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EOS72496.1}.
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DR   EMBL; ASTD01000118; EOS72496.1; -; Genomic_DNA.
DR   RefSeq; WP_016222039.1; NZ_KE159725.1.
DR   AlphaFoldDB; R9MP97; -.
DR   STRING; 1235798.C817_05431; -.
DR   PATRIC; fig|1235798.3.peg.5711; -.
DR   eggNOG; COG1940; Bacteria.
DR   HOGENOM; CLU_036604_13_5_9; -.
DR   OrthoDB; 9796533at2; -.
DR   Proteomes; UP000014211; Unassembled WGS sequence.
DR   CDD; cd00012; NBD_sugar-kinase_HSP70_actin; 1.
DR   Gene3D; 3.30.420.40; -; 2.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR000600; ROK.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR18964:SF177; N-ACETYLMANNOSAMINE KINASE; 1.
DR   PANTHER; PTHR18964; ROK (REPRESSOR, ORF, KINASE) FAMILY; 1.
DR   Pfam; PF00480; ROK; 1.
DR   SUPFAM; SSF53067; Actin-like ATPase domain; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000014211}.
SQ   SEQUENCE   403 AA;  44669 MW;  E182550C574DBCA7 CRC64;
     MKNGMNQDGV QKINRILIVR LLREAGSCSR ADLARMSGLR PATITNIVNE LKHIRLIREE
     GAINAGRGRN GVAISLDTSY YRVVGVRVSR KYFLAGLFDI VGNELESSRY EFAEDETPKE
     RFERIQEQIG AILKRVKEEK VVAIGIAIPG PFFRNHDSQE KGFEFQDWPE ISIERLLKER
     FGVYVFVEHD ANAGALGSYW QMNVGQEKML VYFSAGQGIG AGFVNGGKLI LGALGVAGEI
     GHMTVETNGI LCKCGNYGCL EMYCSSTVLV NRVNKKLTKG NYSILKEGCD LEKIGNAARA
     GDKLTVAEYE RECSYLGVGV VNIMNILNPD IVVIGDELAR ILPETMKECV LKVVQDRMNP
     IVREHTDIYI VGDKEDLSLK GAAIVAIEGL LDEPIAFEWA EEQ
//