ID R9ND91_9FIRM Unreviewed; 496 AA.
AC R9ND91;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE SubName: Full=Threonine synthase {ECO:0000313|EMBL:EOS81264.1};
GN ORFNames=C817_00921 {ECO:0000313|EMBL:EOS81264.1};
OS Dorea sp. 5-2.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Dorea.
OX NCBI_TaxID=1235798 {ECO:0000313|EMBL:EOS81264.1, ECO:0000313|Proteomes:UP000014211};
RN [1] {ECO:0000313|EMBL:EOS81264.1, ECO:0000313|Proteomes:UP000014211}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=5-2 {ECO:0000313|EMBL:EOS81264.1,
RC ECO:0000313|Proteomes:UP000014211};
RG The Broad Institute Genomics Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Earl A., Xavier R., Elson C., Duck W., Walker B., Young S., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Dorea bacterium 5-2.";
RL Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933,
CC ECO:0000256|PIRSR:PIRSR604450-51};
CC -!- SIMILARITY: Belongs to the threonine synthase family.
CC {ECO:0000256|ARBA:ARBA00005517}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EOS81264.1}.
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DR EMBL; ASTD01000018; EOS81264.1; -; Genomic_DNA.
DR RefSeq; WP_016217689.1; NZ_KE159726.1.
DR AlphaFoldDB; R9ND91; -.
DR STRING; 1235798.C817_00921; -.
DR PATRIC; fig|1235798.3.peg.987; -.
DR eggNOG; COG0498; Bacteria.
DR HOGENOM; CLU_015170_3_1_9; -.
DR OrthoDB; 9763107at2; -.
DR Proteomes; UP000014211; Unassembled WGS sequence.
DR CDD; cd01560; Thr-synth_2; 1.
DR Gene3D; 3.40.50.1100; -; 2.
DR Gene3D; 3.90.1380.10; Threonine synthase, N-terminal domain; 1.
DR InterPro; IPR029144; Thr_synth_N.
DR InterPro; IPR037158; Thr_synth_N_sf.
DR InterPro; IPR004450; Thr_synthase-like.
DR InterPro; IPR001926; TrpB-like_PALP.
DR InterPro; IPR036052; TrpB-like_PALP_sf.
DR NCBIfam; TIGR00260; thrC; 1.
DR PANTHER; PTHR43515; THREONINE SYNTHASE-LIKE 1; 1.
DR PANTHER; PTHR43515:SF1; THREONINE SYNTHASE-LIKE 1; 1.
DR Pfam; PF00291; PALP; 1.
DR Pfam; PF14821; Thr_synth_N; 1.
DR SUPFAM; SSF53686; Tryptophan synthase beta subunit-like PLP-dependent enzymes; 1.
PE 3: Inferred from homology;
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW ECO:0000256|PIRSR:PIRSR604450-51};
KW Reference proteome {ECO:0000313|Proteomes:UP000014211}.
FT DOMAIN 5..80
FT /note="Threonine synthase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF14821"
FT DOMAIN 88..421
FT /note="Tryptophan synthase beta chain-like PALP"
FT /evidence="ECO:0000259|Pfam:PF00291"
FT MOD_RES 112
FT /note="N6-(pyridoxal phosphate)lysine"
FT /evidence="ECO:0000256|PIRSR:PIRSR604450-51"
SQ SEQUENCE 496 AA; 54625 MW; 79254CAE10AAA1AD CRC64;
MNLYYKSTRN SELRVTASEA ILKGLAPDGG LFVPEEMPVL DVPMEELKGM TYQETAYAVM
KQFLTDFTES ELKNCIAKAY DPKFDTEEIA PLAKVDDIYY LELFHGATIA FKDMALSILP
HLMTTSAKKN HVENKIVILT ATSGDTGKAA LAGFADVEGT RIIVFYPKNG VSKVQELQMV
TQKGNNVDVV AIHGNFDDAQ SGVKAIFEDK EFAAELAQSG YQFSSANSIN IGRLVPQVVY
YVYAYAKLLE NEEIADGEEI NVVVPTGNFG NILAAYYAKQ MGVPIAKLVC ASNENKVLFD
FFQTGTYDKN REFVLTSSPS MDILISSNLE RLIYLIAGED SVKTKELMEA LSGSGSYTIT
EEMRAKLADF AAGYASEDET AGQIRAVCEK TGYVMDTHTA VASYVCGQYR SKTEDQRKCV
VASTASPYKF VKSVMTAIDE KYVPADEFEL LKELQDTSGI AMPHAIEEIL HAKILHTLEC
DSDKMKEIVK GLCISC
//
