ID   R9PN07_AGAAL            Unreviewed;       336 AA.
AC   R9PN07;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 22.
DE   SubName: Full=N-acetylneuraminate synthase {ECO:0000313|EMBL:GAD02762.1};
DE            EC=2.5.1.56 {ECO:0000313|EMBL:GAD02762.1};
GN   ORFNames=AALB_2842 {ECO:0000313|EMBL:GAD02762.1};
OS   Agarivorans albus MKT 106.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC   Alteromonadaceae; Agarivorans.
OX   NCBI_TaxID=1331007 {ECO:0000313|EMBL:GAD02762.1, ECO:0000313|Proteomes:UP000014461};
RN   [1] {ECO:0000313|EMBL:GAD02762.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Yasuike M., Nakamura Y., Kai W., Fujiwara A., Fukui Y., Satomi M., Sano M.;
RT   "Draft Genome Sequence of Agarivorans albus Strain MKT 106T, an Agarolytic
RT   Marine Bacterium.";
RL   Genome Announc. 1:e00367-13(2013).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:GAD02762.1}.
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DR   EMBL; BARX01000019; GAD02762.1; -; Genomic_DNA.
DR   RefSeq; WP_016402529.1; NZ_BARX01000019.1.
DR   AlphaFoldDB; R9PN07; -.
DR   STRING; 1331007.AALB_2842; -.
DR   OrthoDB; 9781701at2; -.
DR   Proteomes; UP000014461; Unassembled WGS sequence.
DR   GO; GO:0050462; F:N-acetylneuraminate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0016051; P:carbohydrate biosynthetic process; IEA:InterPro.
DR   CDD; cd11615; SAF_NeuB_like; 1.
DR   Gene3D; 3.20.20.70; Aldolase class I; 1.
DR   Gene3D; 3.90.1210.10; Antifreeze-like/N-acetylneuraminic acid synthase C-terminal domain; 1.
DR   InterPro; IPR006190; AFP_Neu5c_C.
DR   InterPro; IPR036732; AFP_Neu5c_C_sf.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR013132; Neu5Ac_N.
DR   InterPro; IPR013974; SAF.
DR   PANTHER; PTHR42966; N-ACETYLNEURAMINATE SYNTHASE; 1.
DR   PANTHER; PTHR42966:SF1; SIALIC ACID SYNTHASE; 1.
DR   Pfam; PF03102; NeuB; 1.
DR   Pfam; PF08666; SAF; 1.
DR   SUPFAM; SSF51269; AFP III-like domain; 1.
DR   SUPFAM; SSF51569; Aldolase; 1.
DR   PROSITE; PS50844; AFP_LIKE; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000014461};
KW   Transferase {ECO:0000313|EMBL:GAD02762.1}.
FT   DOMAIN          278..336
FT                   /note="AFP-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50844"
SQ   SEQUENCE   336 AA;  36708 MW;  7E3175F5CEF1FAD4 CRC64;
     MSCYVIAEIG VNHAGSVALA KKMIDAAKAS GADAVKFQTF TAEKLVSAGT PKVEYQESTT
     ASDESHYAMI KALEFSYTDH IPVFEYCNQL GIDFISTPYD IESAEFLVSI GVTIFKTASA
     DIVDLSLHEY IAKNAELAIV STGMATLGEI ERVVKIYQQA DCKLSLLHCV SNYPCAIQSL
     NLNVISTLKN AFYCDVGYSD HAVGFLPAVI ATTLGATIVE KHFTLDKSMA GPDHKASSDP
     EEFKELVEAI RTTEVALGSP IKTVQTEEMQ MRKISRKSLF SRCFIKQDEK LTADMFVLKR
     PGTGLYEKEL DTILGATATK DISEGEMLRI GDYKLG
//