ID R9UPX0_VITVI Unreviewed; 359 AA.
AC R9UPX0;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=O-methyltransferase OMT4 {ECO:0000313|EMBL:AGN70877.1};
GN Name=OMT4 {ECO:0000313|EMBL:AGN70877.1};
OS Vitis vinifera (Grape).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; Vitales; Vitaceae; Viteae; Vitis.
OX NCBI_TaxID=29760 {ECO:0000313|EMBL:AGN70877.1};
RN [1] {ECO:0000313|EMBL:AGN70877.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23606597; DOI=10.1104/pp.113.218313;
RA Guillaumie S., Ilg A., Rety S., Brette M., Trossat-Magnin C., Decroocq S.,
RA Leon C., Keime C., Ye T., Baltenweck-Guyot R., Claudel P., Bordenave L.,
RA Vanbrabant S., Duchene E., Delrot S., Darriet P., Hugueney P., Gomes E.;
RT "Genetic analysis of the biosynthesis of 2-methoxy-3-isobutylpyrazine, a
RT major grape-derived aroma compound impacting wine quality.";
RL Plant Physiol. 162:604-615(2013).
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DR EMBL; KC517475; AGN70876.1; -; mRNA.
DR EMBL; KC517476; AGN70877.1; -; mRNA.
DR AlphaFoldDB; R9UPX0; -.
DR ExpressionAtlas; R9UPX0; baseline and differential.
DR GO; GO:0008171; F:O-methyltransferase activity; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR016461; COMT-like.
DR InterPro; IPR001077; O_MeTrfase_dom.
DR InterPro; IPR012967; Plant_MeTrfase_dimerisation.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11746; O-METHYLTRANSFERASE; 1.
DR PANTHER; PTHR11746:SF98; O-METHYLTRANSFERASE FAMILY PROTEIN; 1.
DR Pfam; PF08100; Dimerisation; 1.
DR Pfam; PF00891; Methyltransf_2; 1.
DR PIRSF; PIRSF005739; O-mtase; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51683; SAM_OMT_II; 1.
PE 2: Evidence at transcript level;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:AGN70877.1};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000313|EMBL:AGN70877.1}.
FT DOMAIN 35..79
FT /note="Plant methyltransferase dimerisation"
FT /evidence="ECO:0000259|Pfam:PF08100"
FT DOMAIN 129..340
FT /note="O-methyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00891"
FT ACT_SITE 260
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR005739-1"
SQ SEQUENCE 359 AA; 39203 MW; 51A24DABE741FF19 CRC64;
MTEATREMKT LEEEEEGEAG IEMWKYIYGF AAMAAVKCGI ELGIADVMES HGGPITLSAL
SSSLGCPPSG LNRIMRFLVS RRIFREVATS QGDTGYQQTP MSRCLMTSRG DGMAAFVLLE
SSPVMLAPWH GLSARVLGKG NSTFEAAHGD DIWGYAAKNP DHSKLINDAM ASNARRVVPA
MVNDCPEVFD GVGTLVDVGG GNGTALRTLV KACPWIRGIN FDLPHVVATA PKCNDVEHVG
GNMFDSVPKA DAVFIMKVLH DWGDEKCIKI LEKCREAIPE DKGKVIIVEA VIEGDDPQGD
DQKLKDVKLM VDMVMMAHTT TGKERTFKEW DYVLLNAGFS RYTIKPIRSI VQSIIEAYP
//
