ID R9XIR7_ASHAC Unreviewed; 2910 AA.
AC R9XIR7;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=AaceriAER025Cp {ECO:0000313|EMBL:AGO12380.1};
GN ORFNames=AACERI_AaceriAER025C {ECO:0000313|EMBL:AGO12380.1};
OS Ashbya aceri (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX NCBI_TaxID=566037 {ECO:0000313|EMBL:AGO12380.1, ECO:0000313|Proteomes:UP000016920};
RN [1] {ECO:0000313|Proteomes:UP000016920}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23749448; DOI=10.1534/g3.112.002881;
RA Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT loci, numerous translocations, lack of transposons, and distinct gene
RT duplications.";
RL G3 (Bethesda) 3:1225-1239(2013).
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DR EMBL; CP006024; AGO12380.1; -; Genomic_DNA.
DR HOGENOM; CLU_000439_0_0_1; -.
DR OrthoDB; 1356198at2759; -.
DR Proteomes; UP000016920; Chromosome V.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProt.
DR CDD; cd05392; RasGAP_Neurofibromin_like; 1.
DR Gene3D; 3.40.525.10; CRAL-TRIO lipid binding domain; 1.
DR InterPro; IPR036865; CRAL-TRIO_dom_sf.
DR InterPro; IPR039360; Ras_GTPase.
DR InterPro; IPR023152; RasGAP_CS.
DR InterPro; IPR001936; RasGAP_dom.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR PANTHER; PTHR10194:SF150; INHIBITORY REGULATOR PROTEIN IRA1-RELATED; 1.
DR PANTHER; PTHR10194; RAS GTPASE-ACTIVATING PROTEINS; 1.
DR Pfam; PF00616; RasGAP; 1.
DR SMART; SM00323; RasGAP; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS00509; RAS_GTPASE_ACTIV_1; 1.
DR PROSITE; PS50018; RAS_GTPASE_ACTIV_2; 1.
PE 4: Predicted;
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553}.
FT DOMAIN 1536..1725
FT /note="Ras-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50018"
FT REGION 372..402
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 419..443
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2910 AA; 331074 MW; 6A22E6F8E214E84C CRC64;
MVKNLICRIF NRLEQLLPTE LNYSLYSDVE RHPIFSNARL ALLNAGVTQG LQLVVDPLLE
VIERIAEKNR PVSGMTSGVS SAVAAVGVME SYTEDVLHSL LVMLRLLNDI TEVTWQSYEA
SLAEDEAESA REIGGTDGLY STYNVGFSTE KEWTHAIAPP ALETSAAQSL LRISNRFKTR
SQTLAILKKI AGSLHRSGSH NSRIVLPDTL HNERGQTRSE LLDKIDDNCE ALMKYVAASN
PQEYHSYINT RIISPLLVTQ IQNETDIAIY LDAFSFYFIT DRYLSSFLEL VSKMVTSFKK
SVYQEVLLKF VSQAMTAWIL SRPQEYLDII DRIKYQPEDQ STQKLIKEAS FLFEEIYNSF
SVTHILTESP TLQSTMSSPT SAGGSTSSIP GDGTSPAKGG NAAHSINSAT IVITNSVDDS
LRPSTVPDAG EHSNHPRMAS NPNNVENITH ISVLSFLACI VMLHPSAFED VNSTSFRNIP
DDPHADESKE DITDSLYATT SGATSVNSDE CRIRHQHRRL KSFKKLTAFS AHSSTHHKAK
FLSTLVDNLT GMHAVSDAAI FDSLRTLILI SRLSASVFQF EKDTPTIHFS RRLFPVLCDS
LQLCSEQNAR RNPLIAKCLF RHYTLHSNLQ IDYFPVACSL EPDAFNLRLQ EYLEQRNNSL
GHLHILTEGL KAYVSVQTNM PSEFKTLLAT IGLLRRTAYG LSCVLIEGSP LFDGRSSVSA
VIDDLLEGKL VDESNIDNAD DGDSRIPSFM NAFVPKESMK SFPQTPSVPS FGSSSFNEKP
PPAPFIFPSK SDHDAVRIRR PSMGSPQTTL HGRLTTTSSL PHDLERVQYS MRTGMDRGMR
PPLRMSSRGR YGSQDSFMHL VSSTSFVGNE ALQEVKKDAS NLDIVRKIIG NIYTIYKDVL
HFSMSVLDSE KISPLHIDDY KDVVKPIFAA LIDDGADSQS AVKAYCYVGI TCIDQLTGEY
AGRYMPSVFK ANGYLITLLA ASLFNVSLTD SKREQIFSYL TDFWEFRHGI VKYFEKRGIL
SKISDEELYT FPVIRGATGR ALCVSMYSHN PNIHKLLKIG FRLFHKEVEN HHLINGHRIS
TGQFNMQFIR AMGRDSYVAT GALAFQRRLR SDILLRIKHP DRILYDSLRL IYNHWYSLLT
SQNRSSTSSN HFRNCAGFIA ASCGVFLTTD ADILEKFSYL YQVRDSMVEK IDYFIYKQCQ
SINNEDLLTR ENSRDIVSSE LHPLAFAILF KHLKKKTKDL FDIPIAEQEN ELHYVLLEQI
ILVIRVILER DDDTDVLICV SLDLIELLED IFKIIELMPR DSPKYYKIII QISKMLRSFE
HSEQNICISG YMLIKNKWLR LTMRWFESTI FKDYDLENLG KPHRSMDLKR RDLDYLYIDT
SIESSKALAY LTKDLVLEAP QSMSEKELSR SKEVVFGNYF TILLKGLEKS TGIKKFPPTL
RHKIGMLNDN IITSLTNLLN YNVDVGFKYA LPIGYSPNRN IKLAFLKVFV NIVSNFDVTK
KRLEEERSAA IETLLDRAVE DPKLLSKAAR VCPANDIDSL AGSFVTLYDI KNAAHLIVIE
LIIDEISRST RYMDVLRRNS CATRSLSMFS RLKGGAYLIN VLKPVLEEVV STGETFDVEK
IEPDDPDCQR NVDLFCKYLK KLVDSIVGSV ADFPPEFFVI CQSIYSSVKE NFPESAEIAV
GSFIFLRFFC PALVSPDSEG ITDPLYPKAR RSFMILAKVI QNIANGSVSS LKWPALQSEV
EFLKTISDRI FCYLKEISDP TRKVEIRTRP ANRASVDDFH MLHRFLYYHG LEIRREFIND
VQSAEDMGRL RESCRLADRL LSLLGQPRME FKSAISPYIR DHMDTNPELY EFMSRHSLKN
ILPEDTPFVR EGVSPDGFPI IVLTWHLCDK ILKRESDALV FRIFQIYSKV WTTSHYCVID
CTGFDCKKYE EPVRKLSSLF YKLIPVDAAK NCTGFYYYNM TENLLDLWLP IFKDKAGYLS
GLKIPHHFIN SNSPTKTISM LGLSDYSLEV YTDVRVTLHD ASVYNSKDKK FYPVTLKIGN
KHFQVVHDTS KQVKLGLMET ASDVYFNDVF DIADIKSTGL SNEVGEPYEF TILMDNGKKL
IFTSPKCLEI LKIFYYSQVR LEEEFRDDEF GVSSLAHDRN KRKDITYTIG HILMIVFVGL
TSEDDAAESV AYNLMAATQS TFDLDCGHKL TVPPEVYVSG DNSAFYNSIL NTLAVTTPEL
CECIWTFALD LLENVLNKKQ VTALLIALSP WTKNLYEYVY LANDEEGPEI TTQIIRRLIR
ITMKQELHSI LYAQLIFSNI LLEGDLTELL FDEVIHHCVD RASEGAEWKR IIVILTKVPT
TEVCGLVLRK IQKISNSFLP TLQLETSTHS WSELIILVEV AVSLVFDSLL LVQLHLPEIL
CIISLLIDVG PTELRSGLHR LLMNVCHSFV NNERLYGPQK ENLNKISVIF SRQKLKFMFG
FSQDKGRILQ NFSPSSFLTK FTTLEHFISN IFELMSNASV NYSTVLFWKT KYLKYIMDVV
TNVESFLSSR AMMIIGIISK NGINDNLCYK LLRQTFRTLS VPWITDESIF YAISHIFAYS
KIVNGLQPTS KLLPQMFWFS TTYIRSPKSM VYQGGLLLMV NSAQRMSLAV TGENAPPLLS
QLYKEREFVE GVLDEQGRMA RMRFTESNFI HILMAYLSKG LLIPFVRSTA VDALITFFRL
TFHRSHYQDD DNYLVFMLFI YLVQRPDHFN EMMKEMDPDS DIIALDDATG IDARILSWLE
NGSDTALFTL YQGAVYFSSR NSDEPGKIRY LLLLKHLVVK QPFMVFKVYN VIRDELGRIN
TYDVSNTHIV NVAFFVIRLM VVQKDYLKLD DIQQEMQNHL ANRGLSGISD IDIDAAKKES
ELSPEKQIEL IYPRKVQALQ IVEQMLALSE
//
