ID R9XK21_9TELE Unreviewed; 630 AA.
AC R9XK21;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 03-MAY-2023, entry version 37.
DE RecName: Full=Interferon-induced GTP-binding protein Mx {ECO:0000256|ARBA:ARBA00015210};
DE AltName: Full=Interferon-inducible Mx protein {ECO:0000256|ARBA:ARBA00031810};
OS Epinephelus coioides x Epinephelus malabaricus.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Perciformes; Serranoidei; Serranidae; Epinephelinae;
OC Epinephelini; Epinephelus.
OX NCBI_TaxID=1338336 {ECO:0000313|EMBL:AGO14931.1};
RN [1] {ECO:0000313|EMBL:AGO14931.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=K {ECO:0000313|EMBL:AGO14931.1};
RX PubMed=24422212; DOI=10.1016/j.jviromet.2013.10.020;
RA Chen L., Evensen O., Mutoloki S.;
RT "Delayed protein shut down and cytopathic changes lead to high yields of
RT infectious pancreatic necrosis virus cultured in Asian Grouper cells.";
RL J. Virol. Methods 195:228-235(2014).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the TRAFAC class dynamin-like GTPase
CC superfamily. Dynamin/Fzo/YdjA family. {ECO:0000256|RuleBase:RU003932}.
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DR EMBL; KF148054; AGO14931.1; -; mRNA.
DR AlphaFoldDB; R9XK21; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR CDD; cd08771; DLP_1; 1.
DR Gene3D; 1.20.120.1240; Dynamin, middle domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR022812; Dynamin.
DR InterPro; IPR001401; Dynamin_GTPase.
DR InterPro; IPR019762; Dynamin_GTPase_CS.
DR InterPro; IPR045063; Dynamin_N.
DR InterPro; IPR000375; Dynamin_stalk.
DR InterPro; IPR030381; G_DYNAMIN_dom.
DR InterPro; IPR003130; GED.
DR InterPro; IPR020850; GED_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11566; DYNAMIN; 1.
DR PANTHER; PTHR11566:SF225; INTERFERON-INDUCED GTP-BINDING PROTEIN MXA-RELATED; 1.
DR Pfam; PF01031; Dynamin_M; 1.
DR Pfam; PF00350; Dynamin_N; 1.
DR Pfam; PF02212; GED; 1.
DR PRINTS; PR00195; DYNAMIN.
DR SMART; SM00053; DYNc; 1.
DR SMART; SM00302; GED; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00410; G_DYNAMIN_1; 1.
DR PROSITE; PS51718; G_DYNAMIN_2; 1.
DR PROSITE; PS51388; GED; 1.
PE 2: Evidence at transcript level;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134, ECO:0000256|RuleBase:RU003932};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU003932}.
FT DOMAIN 42..315
FT /note="Dynamin-type G"
FT /evidence="ECO:0000259|PROSITE:PS51718"
FT DOMAIN 544..630
FT /note="GED"
FT /evidence="ECO:0000259|PROSITE:PS51388"
SQ SEQUENCE 630 AA; 71199 MW; B6E4D365F010F0DC CRC64;
MTNSTEDQLD KMGSTLNQHY EEKVRPCIDL IDSLRSLGVE KDLALPAIAV IGDQSSGKSS
VLEALSGVAL PRGSGIVTRC PLELKMRRLK EDEPWHGKIS YNGKEEEMYD PADVEKMIRE
AQDEMAGVGV GISDDLISLE ISSPGVPDLT LIDLPGIARV AVKGQPENIG EQIKRLIRKF
ITKQETINLV VVPCNVDIAT TEALQMAQEV DPEGDRTLGI LTKPDLVDKG TEEAVVDIVH
NEVIHLTKGY MIVKCRGQKD IIDRVSLSEA TDKETAFFQD HAHFSTLLDE GFATIPKLAE
KLTLELVHHI EKSLPRLEEQ IEAKVAETQA DLERYGDGPP TEPAERMYFL INKVTAFNQD
IINLTIGEEL KNGYKLNLFS DLRAEFGEWK AQLDFSGHSF QKRVDEEVND FEANYRGREL
PGFINYKTFE VLVKDQLKKL EEPAVKKLKR VTDIVRKGFV QMAQNHFNGF PNLLKSAKAK
IEAIKLDRES SAESMLRTQF RMELIVYTQD STYSHSLDEE KPSTATPSNK TGSLVYRADY
HITLQEMASH LKAYYRIASQ RLADQIPLVI RYLMLQESAA QLQREMLQML QDKENVELLL
KEDYDIGSKR AALQSRLKRL TQARSYLLEF
//
