ID RL22_ASHYP Reviewed; 91 AA.
AC Q44593;
DT 01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE RecName: Full=Large ribosomal subunit protein uL22 {ECO:0000305};
DE AltName: Full=50S ribosomal protein L22;
DE Flags: Fragment;
GN Name=rplV; Synonyms=rpl22;
OS Ash yellows phytoplasma.
OC Bacteria; Mycoplasmatota; Mollicutes; Acholeplasmatales;
OC Acholeplasmataceae; Phytoplasma; 16SrVII (Ash yellows group).
OX NCBI_TaxID=35780;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=8071198; DOI=10.1128/jb.176.17.5244-5254.1994;
RA Gundersen D.E., Lee I.M., Rehner S.A., Davis R.E., Kingsbury D.T.;
RT "Phylogeny of mycoplasmalike organisms (phytoplasmas): a basis for their
RT classification.";
RL J. Bacteriol. 176:5244-5254(1994).
CC -!- FUNCTION: This protein binds specifically to 23S rRNA; its binding is
CC stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is
CC important during the early stages of 50S assembly. It makes multiple
CC contacts with different domains of the 23S rRNA in the assembled 50S
CC subunit and ribosome (By similarity). {ECO:0000250}.
CC -!- FUNCTION: The globular domain of the protein is located near the
CC polypeptide exit tunnel on the outside of the subunit, while an
CC extended beta-hairpin is found that lines the wall of the exit tunnel
CC in the center of the 70S ribosome. {ECO:0000250}.
CC -!- SUBUNIT: Part of the 50S ribosomal subunit. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uL22 family.
CC {ECO:0000305}.
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DR EMBL; L26999; AAA83937.1; -; Genomic_DNA.
DR GO; GO:0015934; C:large ribosomal subunit; IEA:InterPro.
DR GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0006412; P:translation; IEA:InterPro.
DR CDD; cd00336; Ribosomal_L22; 1.
DR Gene3D; 3.90.470.10; Ribosomal protein L22/L17; 1.
DR InterPro; IPR001063; Ribosomal_uL22.
DR InterPro; IPR005727; Ribosomal_uL22_bac/chlpt-type.
DR InterPro; IPR047867; Ribosomal_uL22_bac/org-type.
DR InterPro; IPR036394; Ribosomal_uL22_sf.
DR NCBIfam; TIGR01044; rplV_bact; 1.
DR PANTHER; PTHR13501:SF10; 50S RIBOSOMAL PROTEIN L22, CHLOROPLASTIC; 1.
DR PANTHER; PTHR13501; CHLOROPLAST 50S RIBOSOMAL PROTEIN L22-RELATED; 1.
DR Pfam; PF00237; Ribosomal_L22; 1.
DR SUPFAM; SSF54843; Ribosomal protein L22; 1.
PE 3: Inferred from homology;
KW Ribonucleoprotein; Ribosomal protein; RNA-binding; rRNA-binding.
FT CHAIN 1..>91
FT /note="Large ribosomal subunit protein uL22"
FT /id="PRO_0000125112"
FT NON_TER 91
SQ SEQUENCE 91 AA; 10254 MW; 437CF6A4C2EA97B8 CRC64;
MKVKAVAKQV PVTPRKXRLV VDLIRGKKIK EAESILMFTP RSASPILAKL LKSAVANSVH
NFNFNIDDLY VEEIFVNEGI RLPRLFPRAK G
//
