ID RS1_NEIMB Reviewed; 561 AA.
AC Q9JZ44;
DT 26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 27-MAR-2024, entry version 109.
DE RecName: Full=Small ribosomal subunit protein bS1 {ECO:0000305};
DE AltName: Full=30S ribosomal protein S1;
GN Name=rpsA; OrderedLocusNames=NMB1301;
OS Neisseria meningitidis serogroup B (strain MC58).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales; Neisseriaceae;
OC Neisseria.
OX NCBI_TaxID=122586;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MC58;
RX PubMed=10710307; DOI=10.1126/science.287.5459.1809;
RA Tettelin H., Saunders N.J., Heidelberg J.F., Jeffries A.C., Nelson K.E.,
RA Eisen J.A., Ketchum K.A., Hood D.W., Peden J.F., Dodson R.J., Nelson W.C.,
RA Gwinn M.L., DeBoy R.T., Peterson J.D., Hickey E.K., Haft D.H.,
RA Salzberg S.L., White O., Fleischmann R.D., Dougherty B.A., Mason T.M.,
RA Ciecko A., Parksey D.S., Blair E., Cittone H., Clark E.B., Cotton M.D.,
RA Utterback T.R., Khouri H.M., Qin H., Vamathevan J.J., Gill J., Scarlato V.,
RA Masignani V., Pizza M., Grandi G., Sun L., Smith H.O., Fraser C.M.,
RA Moxon E.R., Rappuoli R., Venter J.C.;
RT "Complete genome sequence of Neisseria meningitidis serogroup B strain
RT MC58.";
RL Science 287:1809-1815(2000).
RN [2]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC STRAIN=NZ98/254 / Serogroup B;
RX PubMed=16645985; DOI=10.1002/pmic.200500821;
RA Vipond C., Suker J., Jones C., Tang C., Feavers I.M., Wheeler J.X.;
RT "Proteomic analysis of a meningococcal outer membrane vesicle vaccine
RT prepared from the group B strain NZ98/254.";
RL Proteomics 6:3400-3413(2006).
CC -!- FUNCTION: Binds mRNA; thus facilitating recognition of the initiation
CC point. It is needed to translate mRNA with a short Shine-Dalgarno (SD)
CC purine-rich sequence (By similarity). {ECO:0000250}.
CC -!- MISCELLANEOUS: Present in outer membrane vesicle formulations which are
CC used as vaccines in human.
CC -!- SIMILARITY: Belongs to the bacterial ribosomal protein bS1 family.
CC {ECO:0000305}.
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DR EMBL; AE002098; AAF41676.1; -; Genomic_DNA.
DR PIR; G81099; G81099.
DR RefSeq; NP_274320.1; NC_003112.2.
DR RefSeq; WP_002237993.1; NC_003112.2.
DR AlphaFoldDB; Q9JZ44; -.
DR SMR; Q9JZ44; -.
DR STRING; 122586.NMB1301; -.
DR PaxDb; 122586-NMB1301; -.
DR KEGG; nme:NMB1301; -.
DR PATRIC; fig|122586.8.peg.1633; -.
DR HOGENOM; CLU_015805_2_1_4; -.
DR InParanoid; Q9JZ44; -.
DR OrthoDB; 9804077at2; -.
DR Proteomes; UP000000425; Chromosome.
DR GO; GO:0022627; C:cytosolic small ribosomal subunit; IBA:GO_Central.
DR GO; GO:0003729; F:mRNA binding; IBA:GO_Central.
DR GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR GO; GO:0006412; P:translation; IBA:GO_Central.
DR CDD; cd05687; S1_RPS1_repeat_ec1_hs1; 1.
DR CDD; cd04465; S1_RPS1_repeat_ec2_hs2; 1.
DR CDD; cd05688; S1_RPS1_repeat_ec3; 1.
DR CDD; cd05689; S1_RPS1_repeat_ec4; 1.
DR CDD; cd05690; S1_RPS1_repeat_ec5; 1.
DR CDD; cd05691; S1_RPS1_repeat_ec6; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 6.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR000110; Ribosomal_bS1.
DR InterPro; IPR035104; Ribosomal_protein_S1-like.
DR InterPro; IPR003029; S1_domain.
DR NCBIfam; TIGR00717; rpsA; 1.
DR PANTHER; PTHR10724; 30S RIBOSOMAL PROTEIN S1; 1.
DR PANTHER; PTHR10724:SF7; 30S RIBOSOMAL PROTEIN S1, CHLOROPLASTIC; 1.
DR Pfam; PF00575; S1; 6.
DR PIRSF; PIRSF002111; RpsA; 1.
DR PRINTS; PR00681; RIBOSOMALS1.
DR SMART; SM00316; S1; 6.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 6.
DR PROSITE; PS50126; S1; 6.
PE 1: Evidence at protein level;
KW Reference proteome; Repeat; Ribonucleoprotein; Ribosomal protein;
KW RNA-binding.
FT CHAIN 1..561
FT /note="Small ribosomal subunit protein bS1"
FT /id="PRO_0000320264"
FT DOMAIN 22..88
FT /note="S1 motif 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00180"
FT DOMAIN 106..172
FT /note="S1 motif 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00180"
FT DOMAIN 193..261
FT /note="S1 motif 3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00180"
FT DOMAIN 278..348
FT /note="S1 motif 4"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00180"
FT DOMAIN 365..435
FT /note="S1 motif 5"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00180"
FT DOMAIN 452..521
FT /note="S1 motif 6"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00180"
SQ SEQUENCE 561 AA; 61177 MW; 2CF6FD8DD99D1615 CRC64;
MSMENFAQLL EESFTLQEMN PGEVITAEVV AIDQNFVTVN AGLKSESLID VAEFKNAQGE
IEVKVGDFVT VTIESVENGF GETKLSREKA KRAADWIALE EAMENGDILS GIINGKVKGG
LTVMISSIRA FLPGSLVDVR PVKDTSHFEG KEIEFKVIKL DKKRNNVVVS RRAVLEATLG
EERKALLENL QEGSVIKGIV KNITDYGAFV DLGGIDGLLH ITDLAWRRVK HPSEVLEVGQ
EVEAKVLKFD QEKQRVSLGM KQLGEDPWSG LTRRYPQGTR LFGKVSNLTD YGAFVEIEQG
IEGLVHVSEM DWTNKNVHPS KVVQLGDEVE VMILEIDEGR RRISLGMKQC QANPWEEFAA
NHNKGDKISG AVKSITDFGV FVGLPGGIDG LVHLSDLSWT ESGEEAVRKY KKGEEVEAVV
LAIDVEKERI SLGIKQLEGD PFGNFISVND KGSLVKGSVK SVDAKGAVIA LSDEVEGYLP
ASEFAADRVE DLTTKLKEGD EVEAVIVTVD RKNRSIKLSV KAKDAKESRE ALNSVNAAAN
ANAGTTSLGD LLKAKLSGEQ E
//
