ID   S0AW40_ENTHI            Unreviewed;       426 AA.
AC   S0AW40;
DT   18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT   18-SEP-2013, sequence version 1.
DT   27-MAR-2024, entry version 34.
DE   SubName: Full=Histidine acid phosphatase family protein {ECO:0000313|EMBL:BAN38984.1};
OS   Entamoeba histolytica.
OC   Eukaryota; Amoebozoa; Evosea; Archamoebae; Mastigamoebida; Entamoebidae;
OC   Entamoeba.
OX   NCBI_TaxID=5759 {ECO:0000313|EMBL:BAN38984.1};
RN   [1] {ECO:0000313|EMBL:BAN38984.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=HM-1:IMSS {ECO:0000313|EMBL:BAN38984.1};
RA   Hiranuka K., Kumagai M., Wakaguri H., Suzuki Y., Sugano S., Watanabe J.,
RA   Makioka A.;
RT   "Short 5' UTR of Entamoeba genes.";
RL   Submitted (JUN-2012) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; AK420371; BAN38984.1; -; mRNA.
DR   AlphaFoldDB; S0AW40; -.
DR   VEuPathDB; AmoebaDB:EHI5A_241700; -.
DR   VEuPathDB; AmoebaDB:EHI7A_182230; -.
DR   VEuPathDB; AmoebaDB:EHI8A_214240; -.
DR   VEuPathDB; AmoebaDB:EHI_059910; -.
DR   VEuPathDB; AmoebaDB:KM1_282680; -.
DR   GO; GO:0016791; F:phosphatase activity; IEA:InterPro.
DR   CDD; cd07061; HP_HAP_like; 1.
DR   Gene3D; 3.40.50.1240; Phosphoglycerate mutase-like; 1.
DR   InterPro; IPR033379; Acid_Pase_AS.
DR   InterPro; IPR000560; His_Pase_clade-2.
DR   InterPro; IPR029033; His_PPase_superfam.
DR   InterPro; IPR016274; Histidine_acid_Pase_euk.
DR   PANTHER; PTHR20963:SF8; MULTIPLE INOSITOL POLYPHOSPHATE PHOSPHATASE 1; 1.
DR   PANTHER; PTHR20963; MULTIPLE INOSITOL POLYPHOSPHATE PHOSPHATASE-RELATED; 1.
DR   Pfam; PF00328; His_Phos_2; 1.
DR   PIRSF; PIRSF000894; Acid_phosphatase; 1.
DR   SUPFAM; SSF53254; Phosphoglycerate mutase-like; 1.
DR   PROSITE; PS00616; HIS_ACID_PHOSPHAT_1; 1.
PE   2: Evidence at transcript level;
KW   Disulfide bond {ECO:0000256|PIRSR:PIRSR000894-2};
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..15
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           16..426
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5012813625"
FT   DISULFID        397..402
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000894-2"
SQ   SEQUENCE   426 AA;  49237 MW;  FBED5A56E665309F CRC64;
     MLAVLLVNMA LGCCGYNEDI THCLSTRTPY LLKDIRDPTL DHFTVVHAEL VQRHGSRYPT
     SNDINAMNMM AETFAENSKI TWKNPFPMEM EGELCDRGKQ ELFSLGKYYK GEFKKLFYGK
     SLLNINVTAT FKKRTQDSAI SWLEGFYDDE PEKKQMVIDN KINITVVPKD KDTQLYFHKN
     CRRYVEYEKS SSTHKQSNQY AQMKLNETAN RFIKAIGMTD IDESTSKSLT QLAFTAGAHE
     YVVFNKSDGL LKYFNIRDAH IMEYIKDLET YYTKGNSSEL NYKIAIPLLD SIINGLKLAV
     VNDKNIQLTK QENNILGNFR FAHAETVTPL MTLMGVDIDQ FALTVKLNEA KKNQRKWNMS
     KVSPYSVHFM FVLLKSKKGQ YYVRTYFNQE AIVLPPCGSE ICLFEDFVKY YGKITKDFDY
     NTFCSN
//