ID S0DP91_GIBF5 Unreviewed; 115 AA.
AC S0DP91;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 24-JAN-2024, entry version 38.
DE RecName: Full=Transcription initiation factor IIA subunit 2 {ECO:0000256|ARBA:ARBA00019928, ECO:0000256|PIRNR:PIRNR009415};
GN ORFNames=FFUJ_04541 {ECO:0000313|EMBL:CCT64256.1};
OS Gibberella fujikuroi (strain CBS 195.34 / IMI 58289 / NRRL A-6831) (Bakanae
OS and foot rot disease fungus) (Fusarium fujikuroi).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium fujikuroi species complex.
OX NCBI_TaxID=1279085 {ECO:0000313|EMBL:CCT64256.1, ECO:0000313|Proteomes:UP000016800};
RN [1] {ECO:0000313|EMBL:CCT64256.1, ECO:0000313|Proteomes:UP000016800}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 195.34 / IMI 58289 / NRRL A-6831
RC {ECO:0000313|Proteomes:UP000016800};
RX PubMed=23825955; DOI=10.1371/journal.ppat.1003475;
RA Wiemann P., Sieber C.M., von Bargen K.W., Studt L., Niehaus E.M.,
RA Espino J.J., Huss K., Michielse C.B., Albermann S., Wagner D.,
RA Bergner S.V., Connolly L.R., Fischer A., Reuter G., Kleigrewe K., Bald T.,
RA Wingfield B.D., Ophir R., Freeman S., Hippler M., Smith K.M., Brown D.W.,
RA Proctor R.H., Munsterkotter M., Freitag M., Humpf H.U., Guldener U.,
RA Tudzynski B.;
RT "Deciphering the cryptic genome: genome-wide analyses of the rice pathogen
RT Fusarium fujikuroi reveal complex regulation of secondary metabolism and
RT novel metabolites.";
RL PLoS Pathog. 9:E1003475-E1003475(2013).
CC -!- FUNCTION: TFIIA is a component of the transcription machinery of RNA
CC polymerase II and plays an important role in transcriptional
CC activation. TFIIA in a complex with TBP mediates transcriptional
CC activity. {ECO:0000256|ARBA:ARBA00024733}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PIRNR:PIRNR009415}.
CC -!- SIMILARITY: Belongs to the TFIIA subunit 2 family.
CC {ECO:0000256|ARBA:ARBA00007675, ECO:0000256|PIRNR:PIRNR009415}.
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DR EMBL; HF679024; CCT64256.1; -; Genomic_DNA.
DR AlphaFoldDB; S0DP91; -.
DR STRING; 1279085.S0DP91; -.
DR EnsemblFungi; CCT64256; CCT64256; FFUJ_04541.
DR VEuPathDB; FungiDB:FFUJ_04541; -.
DR HOGENOM; CLU_112964_3_1_1; -.
DR OrthoDB; 5052738at2759; -.
DR Proteomes; UP000016800; Chromosome 2.
DR GO; GO:0005672; C:transcription factor TFIIA complex; IEA:EnsemblFungi.
DR GO; GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; IEA:EnsemblFungi.
DR GO; GO:0017025; F:TBP-class protein binding; IEA:EnsemblFungi.
DR GO; GO:0060261; P:positive regulation of transcription initiation by RNA polymerase II; IEA:EnsemblFungi.
DR GO; GO:0051123; P:RNA polymerase II preinitiation complex assembly; IEA:EnsemblFungi.
DR CDD; cd10014; TFIIA_gamma_C; 1.
DR CDD; cd10145; TFIIA_gamma_N; 1.
DR Gene3D; 2.30.18.10; Transcription factor IIA (TFIIA), beta-barrel domain; 1.
DR Gene3D; 1.10.287.190; Transcription factor IIA gamma subunit, alpha-helical domain; 1.
DR InterPro; IPR009083; TFIIA_a-hlx.
DR InterPro; IPR009088; TFIIA_b-brl.
DR InterPro; IPR003194; TFIIA_gsu.
DR InterPro; IPR015871; TFIIA_gsu_C.
DR InterPro; IPR015872; TFIIA_gsu_N.
DR PANTHER; PTHR10966; TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 2; 1.
DR PANTHER; PTHR10966:SF0; TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 2; 1.
DR Pfam; PF02751; TFIIA_gamma_C; 1.
DR Pfam; PF02268; TFIIA_gamma_N; 1.
DR PIRSF; PIRSF009415; Hum_TFIIA_gamma; 1.
DR SUPFAM; SSF47396; Transcription factor IIA (TFIIA), alpha-helical domain; 1.
DR SUPFAM; SSF50784; Transcription factor IIA (TFIIA), beta-barrel domain; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PIRNR:PIRNR009415};
KW Reference proteome {ECO:0000313|Proteomes:UP000016800};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|PIRNR:PIRNR009415};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|PIRNR:PIRNR009415}.
FT DOMAIN 9..54
FT /note="Transcription initiation factor IIA gamma subunit N-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF02268"
FT DOMAIN 65..108
FT /note="Transcription initiation factor IIA gamma subunit C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF02751"
SQ SEQUENCE 115 AA; 12902 MW; AC474D7598DB924D CRC64;
MATGAQSFYE LYRRSSIGLA LTDTLDDLIS DERINPQLAM KILSNFDQAI TEALQKNVKA
RLQFKGSLDT YRFCDEVWTF LIKNVTFKMD NGSQSVTANK VKIVSCNAKK PGEGQ
//
