ID S0DQ81_GIBF5 Unreviewed; 694 AA.
AC S0DQ81;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 24-JAN-2024, entry version 39.
DE SubName: Full=Related to PRD1-proteinase yscD {ECO:0000313|EMBL:CCT64744.1};
GN ORFNames=FFUJ_04006 {ECO:0000313|EMBL:CCT64744.1};
OS Gibberella fujikuroi (strain CBS 195.34 / IMI 58289 / NRRL A-6831) (Bakanae
OS and foot rot disease fungus) (Fusarium fujikuroi).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium fujikuroi species complex.
OX NCBI_TaxID=1279085 {ECO:0000313|EMBL:CCT64744.1, ECO:0000313|Proteomes:UP000016800};
RN [1] {ECO:0000313|EMBL:CCT64744.1, ECO:0000313|Proteomes:UP000016800}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 195.34 / IMI 58289 / NRRL A-6831
RC {ECO:0000313|Proteomes:UP000016800};
RX PubMed=23825955; DOI=10.1371/journal.ppat.1003475;
RA Wiemann P., Sieber C.M., von Bargen K.W., Studt L., Niehaus E.M.,
RA Espino J.J., Huss K., Michielse C.B., Albermann S., Wagner D.,
RA Bergner S.V., Connolly L.R., Fischer A., Reuter G., Kleigrewe K., Bald T.,
RA Wingfield B.D., Ophir R., Freeman S., Hippler M., Smith K.M., Brown D.W.,
RA Proctor R.H., Munsterkotter M., Freitag M., Humpf H.U., Guldener U.,
RA Tudzynski B.;
RT "Deciphering the cryptic genome: genome-wide analyses of the rice pathogen
RT Fusarium fujikuroi reveal complex regulation of secondary metabolism and
RT novel metabolites.";
RL PLoS Pathog. 9:E1003475-E1003475(2013).
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|RuleBase:RU003435};
CC Note=Binds 1 zinc ion. {ECO:0000256|RuleBase:RU003435};
CC -!- SIMILARITY: Belongs to the peptidase M3 family.
CC {ECO:0000256|ARBA:ARBA00006040, ECO:0000256|RuleBase:RU003435}.
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DR EMBL; HF679024; CCT64744.1; -; Genomic_DNA.
DR AlphaFoldDB; S0DQ81; -.
DR EnsemblFungi; CCT64744; CCT64744; FFUJ_04006.
DR VEuPathDB; FungiDB:FFUJ_04006; -.
DR HOGENOM; CLU_001805_1_1_1; -.
DR OrthoDB; 735202at2759; -.
DR Proteomes; UP000016800; Chromosome 2.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004222; F:metalloendopeptidase activity; IEA:UniProtKB-EC.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd06455; M3A_TOP; 1.
DR Gene3D; 3.40.390.10; Collagenase (Catalytic Domain); 1.
DR Gene3D; 1.10.1370.10; Neurolysin, domain 3; 1.
DR InterPro; IPR024079; MetalloPept_cat_dom_sf.
DR InterPro; IPR024077; Neurolysin/TOP_dom2.
DR InterPro; IPR024080; Neurolysin/TOP_N.
DR InterPro; IPR045090; Pept_M3A_M3B.
DR InterPro; IPR001567; Pept_M3A_M3B_dom.
DR PANTHER; PTHR11804; PROTEASE M3 THIMET OLIGOPEPTIDASE-RELATED; 1.
DR PANTHER; PTHR11804:SF84; SACCHAROLYSIN; 1.
DR Pfam; PF01432; Peptidase_M3; 1.
DR SUPFAM; SSF55486; Metalloproteases ('zincins'), catalytic domain; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU003435};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU003435};
KW Metalloprotease {ECO:0000256|ARBA:ARBA00023049,
KW ECO:0000256|RuleBase:RU003435};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|RuleBase:RU003435};
KW Reference proteome {ECO:0000313|Proteomes:UP000016800};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU003435}.
FT DOMAIN 217..680
FT /note="Peptidase M3A/M3B catalytic"
FT /evidence="ECO:0000259|Pfam:PF01432"
SQ SEQUENCE 694 AA; 78287 MW; DD56C998BC40630F CRC64;
MSRKPPQPPP SFTTTPSAIL SKTSSLISST TALEDELSST LTPSTATFSS LLTPILNDDH
AVSKQTLIIR LFSSVSEDKD LRDASRTAEE MLLKANSEAL MRRDIASLVK AVYEKHQRGE
EKLGEEDAYT LFKTHRAYQN TGAGIEDEDV REQYKTAVQE RNEVLVAARK TISESDDGIF
FTREQLTGVP ASILDAMKTN DDGLLKATFK KGHMISIMKH ATSAQTRKAY NIAKESRFPE
NVTRLERAVE LRNSTAQMLG FSTHAELKMQ DKMAKSVESV MEMLNKLRTE LKPLADDEMK
TLFEIKKVYI RDNGTDEDGE DVKRLNAWDW AFYARILEKE RYSVDSLLIS EYFEVNHSLK
GMLKIFEEIF GMVFIPTNAP VWQKDVSVYE AWNAEDQGGE FLGYLYLDLY AREGKYAGAH
SSLIQPGFVT SDNNRHYPSS SLITSLLHTP SQPTLLLHSE LKTMFHELGH AIHKLVTHTN
HQHGCARDFV EIPSILLENW IWVPSVLQRL GKHYSYLSSE YLTFWNAKNE GERPGEVLPE
KLALDIARTK HVNGAHAMLY QVFLALFDLT IHNAEEGRAV DTTRLWNESK TEIMGLGRAD
SIGQASFAHP FRAYDAAYFT YALSKVYATD LWVSHFKADP MDKTTGLRYR KLVLQPGGSK
PELKSLSNFL GREPSDKAYY GEVTSTPGTK SSVL
//
