ID S0J3Z5_9FIRM Unreviewed; 644 AA.
AC S0J3Z5;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE RecName: Full=Flagellar hook-associated protein 2 {ECO:0000256|RuleBase:RU362066};
DE Short=HAP2 {ECO:0000256|RuleBase:RU362066};
DE AltName: Full=Flagellar cap protein {ECO:0000256|RuleBase:RU362066};
GN ORFNames=C805_03291 {ECO:0000313|EMBL:EOT22443.1};
OS Eubacterium sp. 14-2.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae;
OC Eubacterium.
OX NCBI_TaxID=1235790 {ECO:0000313|EMBL:EOT22443.1, ECO:0000313|Proteomes:UP000014176};
RN [1] {ECO:0000313|EMBL:EOT22443.1, ECO:0000313|Proteomes:UP000014176}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=14-2 {ECO:0000313|EMBL:EOT22443.1,
RC ECO:0000313|Proteomes:UP000014176};
RG The Broad Institute Genomics Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Earl A., Xavier R., Elson C., Duck W., Walker B., Young S., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Eubacterium bacterium 14-2.";
RL Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for morphogenesis and for the elongation of the
CC flagellar filament by facilitating polymerization of the flagellin
CC monomers at the tip of growing filament. Forms a capping structure,
CC which prevents flagellin subunits (transported through the central
CC channel of the flagellum) from leaking out without polymerization at
CC the distal end. {ECO:0000256|RuleBase:RU362066}.
CC -!- SUBUNIT: Homopentamer. {ECO:0000256|ARBA:ARBA00011255,
CC ECO:0000256|RuleBase:RU362066}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|RuleBase:RU362066}.
CC Bacterial flagellum {ECO:0000256|RuleBase:RU362066}.
CC -!- SIMILARITY: Belongs to the FliD family. {ECO:0000256|ARBA:ARBA00009764,
CC ECO:0000256|RuleBase:RU362066}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EOT22443.1}.
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DR EMBL; ASSS01000014; EOT22443.1; -; Genomic_DNA.
DR RefSeq; WP_016216308.1; NZ_KE159568.1.
DR AlphaFoldDB; S0J3Z5; -.
DR STRING; 1235790.C805_03291; -.
DR PATRIC; fig|1235790.3.peg.3562; -.
DR eggNOG; COG1345; Bacteria.
DR HOGENOM; CLU_015182_0_2_9; -.
DR OrthoDB; 9776025at2; -.
DR Proteomes; UP000014176; Unassembled WGS sequence.
DR GO; GO:0009421; C:bacterial-type flagellum filament cap; IEA:InterPro.
DR GO; GO:0009424; C:bacterial-type flagellum hook; IEA:UniProtKB-UniRule.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR InterPro; IPR040026; FliD.
DR InterPro; IPR010809; FliD_C.
DR InterPro; IPR003481; FliD_N.
DR PANTHER; PTHR30288; FLAGELLAR CAP/ASSEMBLY PROTEIN FLID; 1.
DR PANTHER; PTHR30288:SF0; FLAGELLAR HOOK-ASSOCIATED PROTEIN 2; 1.
DR Pfam; PF07195; FliD_C; 1.
DR Pfam; PF02465; FliD_N; 1.
PE 3: Inferred from homology;
KW Bacterial flagellum {ECO:0000256|ARBA:ARBA00023143,
KW ECO:0000256|RuleBase:RU362066};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|RuleBase:RU362066};
KW Reference proteome {ECO:0000313|Proteomes:UP000014176};
KW Secreted {ECO:0000256|RuleBase:RU362066}.
FT DOMAIN 10..106
FT /note="Flagellar hook-associated protein 2 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02465"
FT DOMAIN 371..633
FT /note="Flagellar hook-associated protein 2 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07195"
FT COILED 589..616
FT /evidence="ECO:0000256|RuleBase:RU362066"
SQ SEQUENCE 644 AA; 69995 MW; 62BD98360B90394F CRC64;
MPIRLSGLNS GLDTDSIVQE LVSAYRTKQD KYTKAQTKLS WKQESWKDMN TKIYNFYSKT
LSNMRRVGNF NKKTTTVSDE TKAKVTAGAG VVNGTQTLEV KRLATAGYLT GGKIKQAYGG
QITNDTSLSA LGVKSGNLTF DVGGERKTIF VNATDTVADL TKALGEKGIS ANFDVTQQRF
ILSSKTTGVG NDFSFVVNEG DTAAFNMLNS LGLATEENFE AAGGDYAFSS NGMISGSSKF
NGLDLDSTSP SNDLNNLLAL SYKIPTGTMK FNVGGVEKTI TVDENSTWNS LINDFDAAGM
KLEYDSAKGG FNLSSKNGTD AVELVAGKGP DGKPDDSFKV ADSLGLATKK DYQDAGAVET
SGMNLATKQD ATNAQIILNG ALFEGESNDF SINGLNITAT GVSNGAMTIT TSTDVDGVYD
MIKSFFKEYN ELMNSMESAY NAPAAKGYEP LTDDEKEAMS EKEIEKWETK IKDSILRRDE
TLRSVMSNMS MNMAKVFEVD GKKYSLASFG IKTAGYFNAA ENESYAYHID HDEDDAVSSG
NDDKLRKMIA EDPDGVASFF TQLANTVYDG LHEKMQATSS SSIYKVYNDK QMQAEYDEYT
KTIKKWEEKL QAMEEAYYKK FAAMETALGK LQSQTNSLSS LFGG
//
