ID S2IVK8_MUCC1 Unreviewed; 352 AA.
AC S2IVK8;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=Guanine nucleotide-binding protein subunit alpha {ECO:0000313|EMBL:EPB81339.1};
GN ORFNames=HMPREF1544_11956 {ECO:0000313|EMBL:EPB81339.1};
OS Mucor circinelloides f. circinelloides (strain 1006PhL) (Mucormycosis
OS agent) (Calyptromyces circinelloides).
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Mucoromycetes; Mucorales; Mucorineae; Mucoraceae; Mucor.
OX NCBI_TaxID=1220926 {ECO:0000313|EMBL:EPB81339.1, ECO:0000313|Proteomes:UP000014254};
RN [1] {ECO:0000313|Proteomes:UP000014254}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1006PhL {ECO:0000313|Proteomes:UP000014254};
RG The Broad Institute Genomics Platform;
RA Cuomo C., Earl A., Findley K., Lee S.C., Walker B., Young S., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome sequence of Mucor circinelloides f. circinelloides 1006PhL.";
RL Submitted (MAY-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KE124184; EPB81339.1; -; Genomic_DNA.
DR AlphaFoldDB; S2IVK8; -.
DR STRING; 1220926.S2IVK8; -.
DR VEuPathDB; FungiDB:HMPREF1544_11956; -.
DR eggNOG; KOG0082; Eukaryota.
DR InParanoid; S2IVK8; -.
DR OMA; TDAKMVF; -.
DR OrthoDB; 2897309at2759; -.
DR Proteomes; UP000014254; Unassembled WGS sequence.
DR GO; GO:0005834; C:heterotrimeric G-protein complex; IEA:InterPro.
DR GO; GO:0001664; F:G protein-coupled receptor binding; IEA:InterPro.
DR GO; GO:0031683; F:G-protein beta/gamma-subunit complex binding; IEA:InterPro.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0007186; P:G protein-coupled receptor signaling pathway; IEA:InterPro.
DR CDD; cd00066; G-alpha; 1.
DR Gene3D; 1.10.400.10; GI Alpha 1, domain 2-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR002975; Fungi_Gprotein_alpha.
DR InterPro; IPR001019; Gprotein_alpha_su.
DR InterPro; IPR011025; GproteinA_insert.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10218; GTP-BINDING PROTEIN ALPHA SUBUNIT; 1.
DR PANTHER; PTHR10218:SF355; GUANINE NUCLEOTIDE-BINDING PROTEIN G(O) SUBUNIT ALPHA; 1.
DR Pfam; PF00503; G-alpha; 1.
DR PRINTS; PR00318; GPROTEINA.
DR PRINTS; PR01241; GPROTEINAFNG.
DR SMART; SM00275; G_alpha; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF47895; Transducin (alpha subunit), insertion domain; 1.
DR PROSITE; PS51882; G_ALPHA; 1.
PE 4: Predicted;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000014254};
KW Transducer {ECO:0000256|ARBA:ARBA00023224}.
SQ SEQUENCE 352 AA; 40543 MW; 039E4B52F68533E1 CRC64;
MGCCQSTEQV EEKQRNQEID AQIKRDRVNL RREIKMLLLG AGESGKSTIL KQMKLIHDGG
YTPEERESFK EVIFSNTMQS MRVTLEAMSN LGITFDNPEN EGHKRLVLEA PPQIDYLGHE
LVEAIASLWD DQGVQECVQR SNEFQLNDSA RYYFDSILRI GQSNYMPSDQ DVLRSRVKST
GITETTFVIE SLTYRMFDVG GQRSERKKWI HCFENVTALV FLVAISEYDQ VLFEDESVNR
LQESLTLFDS ICNSRWFIKT SIILFLNKID LFAEKLPRSP LGDYFSDYKG GDNYDAACQY
LLQKFISLNT RADTKQIYTH LTCATETKQI KFVMNAINDI LVHDNLRNVG LL
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